Titans vs Chargers Prediction, Game Preview, Live Stream, Odds and Picks
Tennessee Hits LA on Three-Game Skid
Week 14 was very different for the Tennessee Titans and Los Angeles Chargers. Los Angeles beat the Miami Dolphins 23-17 in one of Justin Herbert’s finer performances of the season. On the other hand, the Titans lost 36-22 to the lowly Jacksonville Jaguars.
Will the Titans rebound or will LA keep up the strong play and win back-to-back games for the first time since October?

Let’s check the latest NFL odds, stats, injury reports, and NFL lines for Titans vs Chargers. We’ve plenty of Vegas NFL odds and NFL week 15 picks for you to consider.
Titans vs Chargers NFL Betting Odds
Titans Adept at Grinding Out Close Wins
If this game ends up as close as the odds suggest, the Titans may have the advantage based on prior results. The Chargers are not great at the “war of attrition” games, whereas the Titans excel.
The Titans are so good in these spots that five of their seven wins have come by one score or fewer. This may explain why the Titans won eight straight games against the spread between Weeks 3 and 11.
What it doesn’t explain, however, is why they are 0-3 ATS since.
The Titans will have the best player on the field in Derrick Henry. The running back would be the best player on the field in just about any matchup as he leads the NFL in rushing attempts, ranks second in yards, and third in touchdowns.
Henry couldn’t have picked a better matchup, as the Chargers allow the most yards per carry in the NFL.
Scoop on Free Play from the Locker Room
Chargers are not as Advertised
The Chargers may be 7-6, but Week 14 was the first time they beat a team with a winning record.
That is a pretty damning statistic heading into a matchup against a team with a winning record.
Yet, the Chargers have the fifth-best ROI ATS in the NFL at 17.61% and are +2.50 units.
To best predict the outcome of this game, we need to dig deeper into the games the Chargers are winning and losing. In this case, the Chargers overall are phenomenal, but things go south when LA plays at home. Their ROI plummets to 22nd (-4.52) with 0.30 units lost.
Overall, the Chargers are 2-3 ATS at home and 1-4 ATS as home favorites.
On the plus side, the Titans’ defense offers a juicy matchup for Herbert Co. The Titans allowed 754 passing yards in the last two weeks and Los Angeles has a good chance of carving up Tennessee’s secondary on Sunday.
Titans vs Chargers Game Injuries
Titans vs Chargers Head-to-Head
The teams have played twice since the Chargers moved to Los Angeles, splitting a pair of close decisions in 2018 and 2019.
Titans vs Chargers Game Information
- Game: Titans vs Chargers
- Date/Time: Sunday, Dec. 18, 4:25 p.m. ET.
- Location: SoFi Stadium, Inglewood, CA
- Titans vs Chargers Live stream: NFL Game Pass
Titans vs Chargers Picks & Prediction
Predicted Score: Titans 25, Chargers 24
- Worth Betting on the Moneyline?
Yes. While I don’t love either side in this game, I feel that the Titans at +130 on the money line are a good enough value to take a chance. Just don’t bet the farm.
- Worth Betting ATS?
Yes. Because I expect an outright win from Tennesee, the spread is a viable bet. But it’s not the most profitable.
- Worth Betting on the Totals?
Yes. With neither defense performing particularly well lately, I expect points early and often in Los Angeles.
The odds and predictions in the article are based on the time of writing and publication. They may differ as to when the actual event takes place.