NFL Week 15 Odds Picks & Predictions

I have good and bad news about NFL Week 15. The good news is that there will be no teams on bye. The bad news is that a lot of players are questionable due to COVID-19. The list includes 25 players on active rosters and 11 on practice squads.

The New England Patriots (AFC) and Arizona Cardinals (NFC) remain atop each conference. Believe it or not, if the season ended today, the NFC East would have two representatives in the postseason. A lot can change in the last four weeks but keep an eye on it.

We already have the Week 15 odds fully loaded. Every game is crucial now, so be sure to check ‘em and pick your favorites!

NFL Week 15 Preview

More good news about NFL Week 15, we’ve two games scheduled for Saturday. That’s right, you don’t have to watch Saturday Night Live. The Las Vegas Raiders will visit the Cleveland Browns and the New England Patriots will collide with the Indianapolis Colts.

First, an AFC West matchup awaits us on Thursday Night. The Kansas City Chiefs and the Los Angeles Chargers will fight for the top spot. Sunday is full of divisional matchups, including the New Orleans Saints vs Tampa Bay Buccaneers on Prime Time.

The Minnesota Vikings remain in the Wild Card hunt and they’ll be facing the Chicago Bears on Monday Night. A victory could boost them up to seventh place in the NFC.

The NFL Week 15 odds are ready and waiting as we look through each game.

NFL Games of the Week


  • Kansas City Chiefs (-4)

    VS

    Los Angeles Chargers

    Thursday, December 16th

    The Kansas City Chiefs (9-4) crushed the Las Vegas Raiders to remain atop a very competitive AFC West. Believe it or not, Patrick Mahomes threw two touchdown passes but neither went to Tyreek Hill or Travis Kelce.

    The good news for the Chiefs is that their running game was very productive with three total touchdowns. Clyde Edwards Helaire and Derrick Gore proved they can carry the load and take some pressure off Mahomes’ shoulders.

    Kansas City is 4-1 against the spread in its last five games.

    The Los Angeles Chargers (8-5) also won despite not having veteran Wide Receiver Keenan Allen due to COVID-19. They beat the New York Giants 37-21 thanks to a great performance from Justin Herbert. The second-year Quarterback threw for 275 yards and three touchdowns.

    Herbert connected with nine different receivers, so the Chiefs have a lot to worry about when visiting Sofi Stadium.

    The total has gone under in six of the Chargers’ last nine games played in Week 15.

  • Las Vegas Raiders

    VS

    Cleveland Browns (-6)

    Saturday, December 18th

    Nothing like a good football game on Saturday. Even better if it’s Las Vegas Raiders (6-7) vs Cleveland Browns (7-6), because both are in a must win situation.

    The Raiders lost their last two games and are under .500 for the first time. They must win in Ohio, at least if they want to remain in the Wild Card hunt. Tight End Darren Waller (knee/back) remains questionable. They really need him to return as soon as possible.

    The Raiders are 4-2 Straight Up in their last six games against the Browns.

    Cleveland took advantage of Lamar Jackson’s injury and beat the Baltimore Ravens 24-22. That victory allows them to keep aiming for the AFC North title. The bad news is that Running Back Kareem Hunt suffered an ankle sprain and is expected to miss Week 15.

    Expect Nick Chubb to have a huge game, while D’Ernest Johnson will replace Hunt.

    The Browns are 1-4 ATS in their last five games.

  • New England Patriots

    VS

    Indianapolis Colts (-2)

    Saturday, December 18th

    The New England Patriots (9-4) vs Indianapolis Colts (7-6) is one of the best games scheduled for Week 15. If the season ended today, both would be in the postseason.

    New England has won seven games in a row. Rookie QB Mac Jones has done a decent job, but kudos to the running game and the defense. The Pats come from their bye week, but they beat the Buffalo Bills in Week 13 with 222 rushing yards. I’m telling you, Damien Harris and Rhamondre Stevenson have become one of the best duos in the league.

    The Patriots are 16-3-1 ATS in their last 20 games when playing on the road against Indianapolis

    Beating Jonathan Taylor and the Colts won’t be easy. They also come from their bye week and Taylor is aiming for the MVP award. He leads the league in rushing yards with 1348. He also leads the league in rushing touchdowns with 16.

    Veteran T.Y. Hilton took advantage of the bye week to fully recover from a toe injury. Expect him to be heavily involved. I know Carson Wentz is thankful for that.

    The Colts are 5-1 SU in their last six games against an opponent from the AFC.

  • Dallas Cowboys (-10½)

    VS

    New York Giants

    Sunday, December 19th

    When fully healthy, the Dallas Cowboys (9-4) are one of the best teams in the league. They put an end to Washington’s four-game winning streak by beating them 27-20 in Week 14. CeeDee Lamb, Michael Gallup, and Amari Cooper ended with 50+ yards each, while Corey Clement did a great job replacing Tony Pollard.

    Having a reliable kicker is very important, Greg Zuerlein is one of the best examples. He scored four field goals to seal the deal.

    The Cowboys are 7-2 ATS in their last nine games against the New York Giants.

    Regarding the Giants, Mike Glennon will remain under center if Daniel Jones isn’t cleared for contact. Jones missed their last two games due to a neck injury. Glennon has done a decent job, but not enough to lead them to victory.

    The good news is that RB Saquon Barkley has managed to stay healthy for two straight games. He finished Week 14 with 95 total yards and one touchdown. Expect him to carry the load against the Cowboys at MetLife Stadium.

    New York is 3-6 SU in its last nine games when playing at home against the Cowboys.

  • Houston Texans

    VS

    Jacksonville Jaguars (-3)

    Sunday, December 19th

    The Houston Texans will face the Jacksonville Jaguars with absolutely nothing on the line. Both are officially eliminated from the postseason thanks to a 2-11 record. Well, I guess you could say they’ll compete for the No. 1 pick in the 2022 NFL Draft.

    Rookie QB Davis Mills will be the Texans’ starter for the rest of the season. He has potential, but he needs to be more consistent. Last week, he threw for 331 yards and one touchdown. When they faced the Bills, he threw for 87 yards and four interceptions.

    The Texans really need to find a reliable RB. Rex Burkhead, Royce Freeman, and David Johnson aren’t the answer.

    Houston is 4-2 ATS in its last six divisional games.

    The Jaguars come from a 20-0 loss against the Tennessee Titans. That’s right, they couldn’t even score a field goal. Trevor Lawrence threw for 221 yards and four interceptions. Again, inconsistency. Despite those awful numbers, they ran the ball only eight times, that’s ridiculous.

    Jacksonville is 0-5 ATS in its last five games played in December.

  • Tennessee Titans (-2)

    VS

    Pittsburgh Steelers

    Sunday, December 19th

    The Tennessee Titans (9-4) are still fighting for the No. 1 spot in the AFC. A.J Brown remains out due to injury, but Julio Jones is back. The veteran WR returned in Week 14 and finished with four receptions for 33 yards. Come on, give him some time.

    Derrick Henry also remains out, but D’Onta Foreman has shown some improvement over the last couple of weeks. In Week 13, he ran for 109 yards. Last week, he ran for 47 yards and one touchdown.

    The total has gone over in seven of Tennessee’s last eight games on the road.

    Pittsburgh fought bravely in Week 14 against the Minnesota Vikings, but it wasn’t enough. They lost three of their last four games and a lot of people think Ben Roethlisberger should get benched.

    Roethlisberger isn’t the same, I’ll give that. However, it’s not his fault that a WR celebrates a 1&10 as if they had won the Super Bowl.

    They can’t afford to lose against the Titans, at least if they want to remain in the Wild Card hunt.

    Pittsburgh is 4-1 SU in its last five games when playing at home against Tennessee.

  • New York Jets

    VS

    Miami Dolphins (-10)

    Sunday, December 19th

    The New York Jets (3-10) hope is gone. They got officially eliminated from the postseason after losing to the New Orleans Saints in Week 14. They didn’t have much of a chance with Corey Davis and Elijah Moore out due to injury.

    Rookie QB Zach Wilson showed some improvement over the last few weeks, but not enough to silence the critics.

    The Jets are 0-7 ATS in their last seven games against Miami.

    The Dolphins (6-7) won their last five games in a row and will come well-rested after enjoying their bye week. Tua Tagovailoa didn’t throw an interception in their last two games. If he can keep the pace, the Dolphins have a real shot.

    Myles Gaskin, Salvon Ahmed, and Phillip Lindsay landed on the reserve/COVID-19 list. Malcolm Brown could be the answer. He’s expected to return from the injured reserve this week.

    Miami is 5-0 SU in their last five games when playing at home against the Jets.

  • Washington Football Team

    VS

    Philadelphia Eagles (-5)

    Sunday, December 19th

    Taylor Heinicke and the Washington Football Team (6-7) have performed above expectations. If the season ended today, they would be in the postseason as the No. 7 seed in the NFC. Yes, they just lost to the Cowboys, but they put up a good fight.

    The good news is that they found a replacement for RB J.D. McKissic, who remains questionable. Jaret Patterson ran for 29 yards in four carries. Jonathan Williams ran for 16 yards and one touchdown, also in four carries. That’s good news because Antonio Gibson is going to need some rest from time to time.

    Washington is 5-12 SU in its last 17 games played in December.

    The Philadelphia Eagles (6-7) didn’t play in Week 14. Jalen Hurts is expected to be back under center. The second year QB missed their Week 13 game due to injury and Gardner Minshew led them to victory. The Moustache threw for 242 yards and two touchdowns.

    Miles Sanders also took advantage of their bye week to fully heal. With him, the Eagles have a better chance to beat WFT.

    The total has gone over in five of Philadelphia’s last seven games when playing at home against Washington.

  • Arizona Cardinals (-14)

    VS

    Detroit Lions

    Sunday, December 19th

    The Arizona Cardinals (10-3) lost to the Los Angeles Rams and fell to third place in the NFC. Kyler Murray finished with more than 400 yards in total but threw two interceptions.

    The good news for the Cardinals is that RB James Conner is finally meeting expectations. He finished with 125 total yards and two touchdowns. Also, Chase Edmonds is expected to be back in time to face the Detroit Lions.

    Arizona is 8-3 ATS in its last 11 games.

    The Detroit Lions (1-11-1) went back to the losing column. They couldn’t compete with the Denver Broncos and lost 38-10. To be fair, the Lions are one of the most affected teams due to COVID-19.

    D’Andre Swift and Jamaal Williams are expected to be back. Craig Reynolds did a decent job in Denver, 83 yards in 11 carries, but he can’t do it all.

    The total has gone over in the Lions’ last six games when playing at home against Arizona.

  • Carolina Panthers

    VS

    Buffalo Bills (-11)

    Sunday, December 19th

    No Christian McCaffrey, no party. The Carolina Panthers (5-8) lost again despite having rushed for two touchdowns. Cam Newton isn’t a bad QB, but he’s not the most reliable option. In fact, Phillip Walker got some playing time and threw for 75 yards, one touchdown, and one interception.

    Chubba Hubbard did a decent job as the starting RB, but he’s not a dual threat. Ameer Abdullah could be more involved in the game plan from now on.

    The Panthers are 2-5 SU in their last seven games against the Buffalo Bills.

    Speaking about Buffalo, the Bills welcome Carolina in a must win situation. They currently sit in the AFC East second place with a 7-6 record, two games behind the Patriots. Josh Allen is having a good season, but the team lacks chemistry.

    The Bills need to come up with a solution for their backfield. Allen can’t do it all.

    Buffalo is 8-1 ATS in its last nine games against an opponent from the NFC.

  • Cincinnati Bengals

    VS

    Denver Broncos (-1)

    Sunday, December 19th

    On paper, Cincinnati Bengals vs Denver Broncos isn’t a particularly appealing game, but both are in the Wild Card hunt.

    Both are 7-6, but the Bengals are running out of gas. They lost their last two games while also allowing 26 points or more. The duo of Joe Burrow and Ja’Marr Chase remains one of the best in the league, but it’s not enough.

    The Bengals are 1-10 SU in their last 11 games when playing on the road against Denver.

    On the other hand, the Broncos crushed the Detroit Lions in Week 14 to regain some confidence. Melvin Gordon and Javonte Williams combined for four touchdowns. Keep an eye on that duo as well.

    Rumor has it that Teddy Bridgewater is aiming for a multiannual contract up to $20 million per season. If that’s true, he needs to start producing better numbers, otherwise, he could be on the move, once again.

    The total has gone under in five of Denver’s last seven games at home.

  • Atlanta Falcons

    VS

    San Francisco 49ers (-10)

    Sunday, December 19th

    Believe it or not, the Atlanta Falcons (6-7) still have a chance to get into the postseason. They’ve managed to overcome a lot of trouble, including the absence of Calvin Ridley, who remains out. I don’t think he’s coming back this season.

    Russell Gage and Kyle Pitts need to step up. Cordarrelle Patterson’s back must be crushed from carrying the offense all season long.

    The Falcons are 3-12 SU in their last 15 games when playing on the road against the 49ers.

    San Francisco (7-6) is on the rise. They beat the Bengals despite not having Elijah Mitchell due to injury. The rookie RB could be back for Week 15. If not, Jeff Wilson and Deebo Samuel will carry the load from the backfield.

    The good news is that TE George Kittle is looking more confident. He’s their best weapon when it comes to the passing game.

    San Francisco is 3-8 ATS in its last 11 games against an opponent from the NFC South.

  • Seattle Seahawks

    VS

    Los Angeles Rams (-7)

    Sunday, December 19th

    Russell Wilson needed several games to regain confidence, but it seems like he finally did. Even so, the Seattle Seahawks can’t afford to lose to the Los Angeles Rams. They’re at the bottom of the NFC West with a 5-8 record. However, they still have a chance to become a Wild Card team.

    Rashaad Penny had a great game in Week 14 against the Texans. He ran for 137 yards and two touchdowns. If he can keep up producing those numbers, Seattle will become a very dangerous team.

    Seattle is 2-4 ATS in its last six divisional games.

    The Rams come from a huge divisional victory over the Cardinals. Cooper Kupp remains the team’s best receiver, but Odell Beckham is also doing a great job. Matthew Stafford has no excuses.

    Darrell Henderson didn’t play the last two games. Sony Michel did a good job, but he’s not as consistent as Henderson, who’s expected to be back for this crucial game.

    The total has gone under in 11 of the Rams’ last 14 games at home.

  • Green Bay Packers (-4½)

    VS

    Baltimore Ravens

    Sunday, December 19th

    Aaron Rodgers is a man of his word. He’s having a great season, enough for the Green Bay Packers to sit in first place over the NFC. With Rodgers, Davante Adams, and Aaron Jones fully healthy, we’re talking about a very tough team to beat.

    They own a 10-3 record. All their losses were on the road, so it would be very important for them to finish in first place.

    Green Bay is 5-1 ATS in its last six games on the road.

    The Baltimore Ravens could play host to the Packers without Lamar Jackson. The QB remains questionable due to injury. He wants to play, but the team won’t risk it if it’s not necessary. The thing is that they can’t afford to lose. They only have a one-game advantage over the Browns and Bengals in the AFC North.

    Baltimore is 8-1 in its last nine games when playing at home.

  • New Orleans Saints

    VS

    Tampa Bay Buccaneers (-11)

    Sunday, December 19th

    Alvin Kamara returned to action and the New Orleans Saints looked completely different. He finished the game against the Jets with 145 total yards and one touchdown. He took a lot of pressure off Taysom Hill’s shoulders.

    The Saints desperately need a reliable WR. Marquez Callaway and Tre’Quan Smith have done a decent job, but they really miss Michael Thomas.

    New Orleans is 15-5 SU in its last 20 games on the road.

    The Tampa Bay Buccaneers are right on track to another NFC South title. They sit in first place with a 10-3 record. Most recently, they beat the Bills 33-27 with another great performance from Tom Brady and Leonard Fournette.

    With Antonio Brown out, they recently signed Breshad Perriman and he already scored. Chris Goodwin, Mike Evans, Rob Gronkowski, and Perriman should be more than enough to fight for the Lombardi.

    Tampa Bay is 4-1 ATS in its last five games played in December. They shouldn’t have too much trouble getting another W over the Saints.

  • Minnesota Vikings (-3½)

    VS

    Chicago Bears

    Monday, December 20th

    The Minnesota Vikings (6-7) won a thriller in Week 14 against Pittsburgh to remain in the Wild Card race. Dalvin Cook returned and ran for 205 yards and two touchdowns. K.J. Osborn did a great job replacing Adam Thielen, who remains questionable.

    Kirk Cousins needs to stop making mistakes. They had a comfortable advantage over the Steelers, but two interceptions complicated things.

    The Vikings are 1-4 SU in their last five games played in December.

    Justin Fields needs more time, but he has shown a lot of potential. The Chicago Bears (4-9) fought bravely against the Packers in Week 14, but it wasn’t enough.

    The good news is that RB David Montgomery has managed to stay healthy. He’s one of the best dual-threat RB’s in the league when that happens.

    Chicago is 3-6 SU in its last nine games against an opponent from the NFC North.

NFL Week 15 News

Our NFL news page has all the NFL Week 15 content you could want. That’s right, you will be able to find the latest team, player and NFL News, stats, NFL injuries & weather reports, highlights and betting trends for all 32 teams right before you head to the NFL Week 15 Odds to place your ticket!

NFL Week 15 Picks

After an in-depth analysis of the Football Betting Lines for Week 15 alongside the latest NFL Week 15 News, our panel of experts share their NFL picks for all 16 NFL Week 15 matchups. Here’s the rundown.

NFL Week 15 Preview & Early NFL Picks | NFL Lines, Best Odds + TNF Picks

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