Let’s start with a friendly reminder: no teams on bye yet! That’s right, teams will begin to rest starting Week 6. Now, onto a question: what can you expect after a week in which both New York teams won? That’s right, more surprises only the NFL can provide.
We’re down to only two winless teams, while the unbeaten column was reduced to one. We already have the Week 5 odds fully loaded. Be sure to check ‘em and pick your favorites!
NFL Week 5 Preview
Action will begin on Thursday Night with an exceptional divisional matchup. Aaron Donald and the Los Angeles Rams will face Russell Wilson and the Seattle Seahawks. On Sunday, Tom Brady will begin his second round of beating all the NFL teams against the Miami Dolphins.
That’s not all, we’ll also have more divisional matchups and a rematch of last season’s AFC Championship game. The NFL Week 5 odds are ready and waiting as we look through each game.
NFL Games of the Week
Los Angeles Rams (-2)
Seattle SeahawksOctober 7, 8:20 p.m. ET
Believe it or not, Aaron Donald isn’t among the top 10 players with the most sacks so far this season. Nevertheless, he remains a dominant player, especially when playing against divisional rivals.
Offensively, the Rams have found a new hope in Matthew Stafford. The veteran quarterback has thrown for 1,222 yards, 11 touchdowns, and only two interceptions. He and receiver Cooper Kupp have become one of the best duos in the league.
LA is 3-1 after losing 37-20 to the Arizona Cardinals. Losing two divisional matchups in a row is simply unacceptable for them.
Winning in Seattle won’t be easy though. The Seahawks (2-2) come from a huge 28-21 victory over San Francisco and their confidence is up to the roof. Russell Wilson remains among the best QB’s in the league, while Alex Collins seems to be the answer at backfield.
The Seahawks lost their home opener to Tennessee. They can’t afford to lose, otherwise Arizona and LA could get away at the top of the NFC West.
Expect quite a show. The total has gone over in four of the Rams’ last five games when playing on the road against Seattle.
New York Jets (-3½)
Atlanta FalconsOctober 10, 9:30 a.m. ET
London here we go! The Atlanta Falcons will play host to the New York Jets in the first game of the 2021 International Series. Both are in a must win situation after starting the season 1-3. However, the Jets have the morale advantage.
Rookie QB Zach Wilson led them to their first victory last week. They beat Tennessee 27-24 despite having allowed 157 rushing yards from Derrick Henry. Offensively, they’re very inconsistent, but defensively they’ve shown some true potential. Head coach Robert Saleh has done a great job in that regard.
Matt Ryan and the Atlanta Falcons are a disaster. Last week, Ryan threw for four touchdowns, three to WR Cordarrelle Patterson, and they still lost. That’s not all, they lost to the Washington Football Team, at home!
This looks like the perfect game to return to the winning column, but their defense needs a complete overhaul. Maybe not playing in front of their home crowd will take some of the pressure off.
Both are 1-4 against the spread in their last five games.
Detroit Lions (-7½)
Minnesota VikingsOctober 10, 1:00 p.m. ET
Jared Goff is a decent QB, but he can’t do it all. D’Andre Swift, who’s supposed to be their top RB, finished last week’s game with eight carries for 16 yards. That’s ridiculous. Of course, they lost, and now they’re 1-3 at the bottom of the NFC North.
Beating a divisional foe would be huge to keep hope alive, but they definitely deserve to be the underdogs. Their defense lacks experience, and they’ll be facing one of the best receiver duos in the league.
The Minnesota Vikings (1-3) also are in a must win situation. However, they’ll play host to the Lions with more questions than answers. RB Dalvin Cook returned last week, but he wasn’t at 100%. They need him to keep winning, otherwise it will be bye-bye postseason.
QB Kirk Cousins needs to work on his leadership skills. If Cook isn’t at 100%, he needs to lead the team to victory. Receivers Justin Jefferson and Adam Thielen have been great, but you can’t depend on two players during the entire season.
Odds and numbers are not looking good for the Lions. They’re 1-13 straight up in their last 14 games against an opponent from the NFC North.
New Orleans Saints (-1)
Washington Football TeamOctober 10, 1:00 p.m. ET
Jameis Winston isn’t a bad QB, but he isn’t good either. His Week 1 performance was a mirage. Last week, against the Giants, he threw for 226 yards and one touchdown. He couldn’t take advantage of an incredible performance from Alvin Kamara (120 rushing yards).
Defensively, the Saints are a solid team, but they need to crush teams like these to be taken seriously. They’re 2-2 and there’s plenty of football to be played, but their visit to the capital won’t be easy.
The Washington Football Team got their second victory of the season against Atlanta. They keep fighting for the top of the NFC, currently held by Dallas with a 3-1 record.
QB Taylor Heinicke keeps proving he deserves to be a starting QB in the NFL. Also, WR Terry McLaurin keeps proving he’s elite. Last but not least, RB Antonio Gibson keeps showing tremendous potential. Oh, and don’t forget their defense is led by Chase Young, who’s eager to prove he’s one of the best.
Expect fireworks. The total has gone over in New Orleans’ last seven visits to Washington.
New England Patriots (-10)
Houston TexansOctober 10, 1:00 p.m. ET
The New England Patriots almost beat Tom Brady and the Tampa Bay Buccaneers. Head coach Bill Belichick proved, once again, why he’s one of the best to ever do it. They didn’t allow Brady to throw a single touchdown pass. He threw 10 in the first three games of the season.
Rookie QB Mac Jones had one of his best games throwing for 275 yards and two touchdowns. His confidence is growing each week. Offensive coordinator Josh McDaniels needs to figure out a solution for the running game. Otherwise, Jones could be very worn mid-season.
The Houston Texans come from a disastrous week. Rookie QB Davis Mills threw for 87 yards and four interceptions against the Buffalo Bills. He’s expected to start against the Patriots, but another similar performance could send him to the bench.
Houston’s backfield should carry the load. It’s unbelievable that having Mark Ingram, David Johnson, and Phillip Lindsay they ran only for 44 yards against Buffalo in Week 4.
The Patriots are 6-0 ATS in their last six games played in Week 5.
Miami Dolphins (-10)
Tampa Bay BuccaneersOctober 10, 1:00 p.m. ET
Jacoby Brissett is a good QB, but he lacks confidence. He knows everybody in Miami is waiting for Tua Tagovailoa to return and show his true potential. The Dolphins will visit the Tampa Bay Buccaneers looking to avoid the 1-4 abyss.
Despite having started only two games, Brissett has developed good chemistry with WR Davante Parker and TE Mike Gesicki. WR Will Fuller keeps battling with injuries, but he should be a fine addition when fully healthy. Especially when going deep.
Tom Brady and the Bucs avoided what would have been an embarrassing loss in New England. They lead the NFC South with a 3-1 record and their schedule over the next few weeks looks very accessible.
Leonard Fournette and Ronald Jones keep sharing the load when it comes to running the football. Rob Gronkowski is expected to miss several weeks due to injury. They’re going to miss him, especially in the red zone, but they should be fine. It’s a great opportunity for Cameron Brate and O.J. Howard.
The Buccaneers are 5-0 SU in their last five games at home. Also, the total went over in six of their last seven games against Miami.
Green Bay Packers (-3½)
Cincinnati BengalsOctober 10, 1:00 p.m. ET
After an embarrassing loss in Week 1, the Green Bay Packers have won three in a row. Aaron Rodgers has been sensational. Davante Adams and Randall Cobb have the potential to become one of the best receiver duos in the league.
Offensively, Green Bay is a well-balanced team. Aaron Jones and AJ Dillon are reliable running backs. Jones is also very good in the passing game, giving Rodgers an easy way out when the pocket collapses.
They’ll face an inspired Cincinnati Bengals team. They lead the AFC North with a 3-1 record and QB Joe Burrow is playing at a high level. He comes from throwing for 348 yards and two touchdowns against Jacksonville.
Burrow has plenty of reliable targets out there. Tyler Boyd, C.J. Uzomah, and Ja’Marr Chase have been great. RB Joe Mixon has done a great job too, but he’s questionable due to an ankle injury.
Expect fireworks between the old and the new school. The total has gone over in six of Green Bay’s last eight games.
Denver Broncos (-1)
Pittsburgh SteelersOctober 10, 1:00 p.m. ET
The Denver Broncos finally woke up. After winning their first three games against three very bad teams, they couldn’t beat Baltimore at Mile High. That’s not all, QB Teddy Bridgewater left the game with a possible concussion and is questionable to face the Pittsburgh Steelers.
To be fair, it seems like the injury bug has something against them. They lost Jerry Jeudy, K.J. Hamler, Bradley Chubb, Josey Jowell, and now Bridgewater is questionable. This could be a great opportunity for Drew Lock, but he didn’t look good against the Ravens.
Luckily for them, they’ll face another bad team in Week 5. On paper, the Steelers aren’t that bad, but on the field, they are, at least the last three weeks. Ben Roethlisberger seems tired all the time, and Juju Smith-Schuster is becoming a one season sensation.
Not everything is bad news though. Rookie RB Najee Harris has been playing really well. Also, T.J. Watt returned from injury and finished with two sacks against the Packers in Week 4.
Expect a close one, 41% of the betting market believes Denver will cover. The total went under in four of both teams’ last five games.
Philadelphia Eagles (-4)
Carolina PanthersOctober 10, 1:00 p.m. ET
After winning in Week 1, the Philadelphia Eagles have lost three in a row. Keep in mind that they beat Atlanta. Last week, they fought bravely against the Chiefs, but it wasn’t enough. QB Jalen Hurts seems like the real deal, but he needs more help.
Rookie WR DeVonta Smith has shown he can be elite, but the rest of the receivers have been very inconsistent. Also, the backfield hasn’t helped much. Especially Miles Sanders, who isn’t meeting expectations.
They’ll travel to Carolina to face a Panthers team that has surprised everybody. They’re 3-1 after losing against Dallas in a back-and-forth battle. They were able to fight despite not having Christian McCaffrey due to injury.
QB Sam Darnold has been leading the way, and WR D.J. Moore has been his best ally. They can’t afford to lose, otherwise Tampa Bay could start getting away.
Expect plenty of points. The total has gone over in four of Philadelphia’s last five games when playing on the road against Carolina.
Tennnessee Titans (-4)
Jacksonville JaguarsOctober 10, 1:00 p.m. ET
Derrick Henry must be having back problems from carrying the Tennessee Titans over the last three seasons. Henry is always in beast mode, even when they lose against the Jets. That’s right, Tennessee lost against the Jets despite Henry finishing the game with 157 yards and one touchdown. They were without Julio Jones and A.J. Brown due to injury, but still.
They still are in control of the AFC South with a 2-2 record. However, they can’t let another winless team beat them, especially when it’s a divisional rival.
That’s right, the Jacksonville Jaguars will play host to the Titans looking for their first victory of the season. Rookie QB Trevor Lawrence showed some improvement last week, but it wasn’t enough to beat the Bengals.
They also showed some improvement in the running game, with James Robinson scoring two touchdowns. Carlos Hyde shouldn’t be a menace for him anymore. If the Jags stick to a balanced offense their winning chances will increase considerably.
Tennessee won eight of their last 10 meetings. Also, the total went over in six of those 10 meetings.
Cleveland Browns (Ev)
Los Angeles ChargersOctober 10, 4:05 p.m. ET
The Cleveland Browns fanbase have a lot to be excited about. Their team is 3-1. Offensively, they own one of the best RB’s duos in the league and Odell Beckham Jr. is back. Defensively, Myles Garrett leads the league with six sacks.
Last week, they limited the Vikings to seven points. That’s right, Dalvin Cook, Adam Thielen, and Justin Jefferson were completely controlled. That’s not an easy thing to do.
They’ll travel to Los Angeles to face another exciting team, the Chargers. QB Justin Herbert has been sensational, leading them to a 3-1 start, including two huge divisional victories over the Chiefs and the Raiders.
RB Austin Ekeler is finally living up to expectations. He has become one of the best dual-threat RB’s in the league.
Expect a fast-paced game, with plenty of red zone action. The total went over in four of Cleveland’s last five games against an opponent from the AFC.
Chigago Bears (-4½)
Las Vegas RaidersOctober 10, 4:05 p.m. ET
Rookie QB Justin Fields got his first professional victory as a starter last week. The thing is that he didn’t do much. He threw for 209 yards and one interception. RB David Montgomery led the way with 106 rushing yards and two touchdowns. The problem is that now Montgomery is going to be out four to six weeks due to a knee injury.
WR Darnell Mooney also had a great game with five receptions for 125 yards. The most important thing is that they won. They were under a lot of pressure, especially head coach Matt Nagy. Getting a W allowed them to regain some confidence.
They’ll collide with the Las Vegas Raiders in a crucial game for both. The Raiders don’t want to lose two games in a row, and they’ve been pretty solid when playing at home. Derek Carr has proven to be a reliable QB, while RB Josh Jacobs is finally back. He missed two weeks due to injury.
Las Vegas needs to focus on improving defensively. Their secondary is very vulnerable, but they should be fine against the run.
The Raiders are 3-7 ATS in their last 10 games, while the Bears are 2-4 ATS in their last six.
New York Giants (-7)
Dallas CowboysOctober 10, 4:25 p.m. ET
The perfect divisional matchup to have a nice afternoon. The New York Giants just got their first victory of the season despite having several players out. WR’s Sterling Shepard and Darius Slayton remain questionable. However, Kenny Golladay regained a lot of confidence with a 116 yards performance against the Saints.
RB Saquon Barkley also regained a lot of confidence after finishing the game in New Orleans with 126 total yards and two touchdowns. He took off a lot of pressure from Daniel Jones’ shoulders.
The Dallas Cowboys lead the NFC East with a 3-1 record. Beating the Giants would allow them to increase the gap between the two even more. I know it’s still early in the season, but it’s never too early to have a comfortable lead.
QB Dak Prescott is already leading the poll for Comeback of the Year. RB Ezekiel Elliott has shown a lot of improvement over the last two weeks. He finished their last game with 143 rushing yards and one touchdown.
The Cowboys are 7-1 SU in their last eight games when playing at home against the Giants. Only 21% believes the Giants can pull off the upset.
San Francisco 49ers (-5½)
Arizona CardinalsOctober 10, 4:25 p.m. ET
Another great divisional matchup. The San Francisco 49ers come from a tough loss against the Seahawks. Losing two divisional matchups in a row would hurt their confidence and their chances big time.
QB Jimmy Garoppolo left the game due to a knee injury. Rookie Trey Lance took over and did it pretty well. He finished with 198 total yards and two touchdown passes.
WR Deebo Samuel has been sensational, while TE George Kittle hasn’t met expectations. Defensively, Nick Bosa is showing why he deserves to be considered among the best in the league.
They’ll face the last remaining unbeaten team in the league. The Arizona Cardinals are 4-0 after crushing the Rams in Week 4. QB Kyler Murray has been exceptional, and now he has A.J. Green and DeAndre Hopkins together out there.
Defensively, Chandler Jones leads the team with five sacks. He’s finally meeting expectations, and he’s learning a lot from J.J. Watt.
The total has gone under in four of Arizona’s last five games when playing at home against San Francisco. Expect a fierce battle.
Buffalo Bills (-2½)
Kansas City ChiefsOctober 10, 8:20 p.m. ET
An AFC Championship Game rematch is scheduled for Sunday Night. The Buffalo Bills are 3-1 thanks to an impressive team effort. They’ve scored 35+ points in their last three games. They allowed a total of 21 points on those same three games.
Josh Allen is now the best QB in the AFC East. They shouldn’t have too much trouble winning the division. That’s why they’ve to beat teams like the Chiefs to be taken seriously. Allen has plenty of weapons to do it with Stefon Diggs, Emmanuel Sanders, and Dawson Knox out there.
The Chiefs have had a rocky start, but they remain a title contender. Patrick Mahomes comes from a five-touchdown passes game, regaining a lot of confidence after two consecutive losses.
Tyrek Hill remains the only reliable WR in the league, but more help is on the way. Apparently, Josh Gordon has impressed since joining the practice squad. Head coach Andy Reid said he has a chance to play on Sunday Night.
Expect fireworks at Arrowhead. The total has gone over in 10 of Buffalo’s 14 games against an opponent from the AFC West.
Indianapolis Colts (-7)
Baltimore RavensOctober 11, 8:15 p.m. ET
The Indianapolis Colts finally won. In Week 3 against the Dolphins, Carson Wentz threw for 228 yards and two touchdowns. RB Jonathan Taylor met expectations and ran for 103 yards and one touchdown. That’s the balance they need in order to keep winning.
WR T.Y. Hilton is not quite ready to return. Wentz has developed good chemistry with Michael Pittman Jr. Zach Pascal, and Mo Alie-Cox. The thing is that none of them is as good as Hilton when going long.
They’ll face a Baltimore Ravens team on the rise. They’ve won three straight games and Lamar Jackson threw for 300+ yards in Week 4. He has been criticized for running a lot.
Latavius Murray became the primary running back and did a decent job. Le’Veon Bell played his first game with the team. He should be more involved in Week 5, but don’t expect him to be the starter.
Baltimore won four of their last five meetings with Indianapolis. Also, the total went under the last eight times they collided.
NFL Week 5 News
Our NFL news page has all the NFL Week 5 content you could want. That’s right, you will be able to find the latest team, player and NFL News, stats, injury & weather reports, highlights and betting trends for all 32 teams right before you head to the NFL Week 5 odds to place your ticket!
NFL Week 5 Picks
After an in-depth analysis of the NFL Week 5 betting lines alongside the latest NFL news, our panel of experts share their betting predictions for all 16 NFL Week 4 matchups. Here’s the rundown.