NFL Week 6

Can you believe it? Week 6 of the NFL regular season is already here and we’ve a lot to talk about. Towards a third part of the season, only one team remains unbeaten, while two remain winless.

Things are starting to clear in several divisions, but Week 5 signed a lot of players into the injury list. That’s right, regarding the National Football League anything can change in the blink of an eye. Just asked Dan Campbell, Detroit Lions’ head coach.

We already have the Week 6 odds fully loaded. Be sure to check ‘em and pick your favorites!

NFL Week 6 Preview

Buckle up because Week 6 action begins on Thursday Night with two very explosive teams. Tom Brady and the Tampa Bay Buccaneers will face Jalen Hurst and the Philadelphia Eagles. On Sunday, the Jacksonville Jaguars and the Detroit Lions will have a great opportunity to get their first victory. Last but not least, Derrick Henry will try to crush the new favorites to win the AFC on Monday Night.

The NFL Week 6 odds are ready and waiting as we look through each game. Don’t forget that at least two teams will be on bye from now on until Week 14. This week it will be the Atlanta Falcons, New York Jets, New Orleans Saints, and San Francisco 49ers.

NFL Games of the Week


  • Tampa Bay Buccaneers (-7)

    VS

    Philadelphia Eagles

    October 14, 8:20 p.m. ET


    Believe it or not, last week Tom Brady had a first time. He threw for 400+ yards and five touchdowns in the same game for the first time in his career. That’s in case you were thinking he doesn’t have enough gas left in the tank or something.
    The Tampa Bay Buccaneers (4-1) recently added veteran cornerback Richard Sherman to their Madden Ultimate team. An addition like Sherman is always welcome, but the team’s offense is carrying the load. The Bucs average 33.4 points per game, third best in the league. Hell, even Antonio Brown is looking sharp.
    They will face the Philadelphia Eagles at Lincoln Financial Field. The Eagles are 1-4 SU in their last five home games. Nevertheless, they come from a huge victory in Carolina, where Hurst proved, again, that he’s a very dangerous dual-threat quarterback.
    I don’t have a doubt they can compete offensively, but I’m not so sure about Philly’s defense. Prior to beating Carolina 21-18, they allowed 41 and 42 points in consecutive weeks. Brady isn’t Sam Darnold.
    Expect fireworks, the total went over in four of their last six meetings in Philadelphia.

  • Miami Dolphins (-3½)

    VS

    Jacksonville Jaguars

    October 17, 9:30 a.m. ET


    Jacoby Brissett hasn’t done a bad job as the Miami Dolphins (1-4) starting QB. Nevertheless, head coach Brian Flores said he’s hopeful for Tua Tagovailoa to return in Week 6. I’m not sure the team will look better with Tagovailoa under center, but at least he draws more media attention.
    Miami’s receivers have had a lot of problems staying healthy. Davante Parker didn’t play last week and remains questionable. Fortunately for them, Miles Gaskin has proven he’s a reliable dual threat running back. He should carry the load on Sunday.
    The Jacksonville Jaguars (0-5) will play host to the Dolphins in London, their second home. Lately, head coach Urban Meyer has been a distraction, but this is a great opportunity to get their first victory.
    James Robinson has also proven he can carry the load from the back. However, rookie QB Trevor Lawrence needs to do his part as well. He has the talent but lacks confidence.
    The Dolphins are 4-2 ATS in their last six games against the Jaguars.

  • Kansas City Chiefs (-6½)

    VS

    Washington Football Team

    October 17, 1:00 p.m. ET


    Believe it or not, the Kansas City Chiefs (2-3) are last in the AFC West. Last week, they were pounded by the Bills. RB Clyde Edwards-Helaire suffered a minor injury that will keep him out for a couple of weeks. It’s time for Darrel Williams to step up.
    Josh Gordon debuted and finished with one reception for 11 yards. He needs more time to adapt and regain confidence, but he and Patrick Mahomes could become a very dangerous duo. I don’t think it’s time to panic yet. However, head coach Andy Reid has a lot of work to do prior to facing the Washington Football Team (2-3).
    The WFT aren’t good enough, but you’ve to admire their passion. QB Taylor Heinicke is living the dream and he has done a decent job. Antonio Gibson keeps building his reputation as a reliable No. 1 running back.
    Defensively, Chase Young must make sure to play at his best, otherwise they won’t have a chance. He recorded his first sack last week, so maybe the beast is about to be unleashed.
    The Chiefs are 7-0 SU in their last seven games against Washington. Only 6% believe the home side will pull off an upset.

  • Los Angeles Rams (-10½)

    VS

    New York Giants

    October 17, 1:00 p.m. ET


    The Los Angeles Rams (4-1) should be really thankful for Matthew Stafford. He keeps throwing for 300+ yards like it’s nothing and has become a leader in the locker room. Last week he connected with seven different receivers. Talk about distribution.
    Now, we’re talking about a well-balanced team. Aaron Donald remains one of the best defensive players in the league. He’s getting more help from Leonard Floyd and Troy Reeder. Don’t forget about Jalen Ramsey, who keeps containing elite receivers each week.
    They shouldn’t have too much trouble beating the New York Giants (1-4), or should I say the New York Hospital? Daniel Jones, Saquon Barkley, and Kenny Golladay couldn’t finish their Week 5 matchup against the Cowboys. Jones is in concussion protocol, while Barkley and Golladay are expected to miss some time.
    The coaching staff is praying for Sterling Shepard and Darius Slayton to get the green light. Otherwise, expect the Giants’ offense to rely on RB Devontae Booker.
    Los Angeles is 5-1 SU in their last six games against opponents from the NFC East.

  • Houston Texans

    VS

    Indianapolis Colts (-10)

    October 17, 1:00 p.m. ET


    Despite losing to the Patriots in Week 5, the Houston Texans (1-4) have one reason to smile. QB David Mills regained a lot of confidence after throwing for 312 yards, three touchdowns and zero turnovers. The coaching staff isn’t expecting Tyrod Taylor to return any time soon.
    The Texans’ debt has been the running game. Having Mark Ingram, David Johnson, and Philip Lindsay it should be a lot better. They need to find that balance, otherwise Mills could be devoured by the pressure.
    They’ll travel to Indianapolis to face a heartbroken team. The Colts () blew a 19-point lead over the Ravens and fell to 1-4. Carson Wentz threw for 400+ yards and RB Jonathan Taylor had a monster game, but that wasn’t enough. That’s why they should be preoccupied, it should have been enough.
    T.Y. Hilton’s return from IR remains unclear. Michael Pittman, Parris Campbell, and Zach Paschal remain Wentz’s best allies.
    Winning this divisional matchup would be huge for either of them. The Colts are 16-3 SU in their last 19 games when playing at home against Houston.

  • Cincinnati Bengals (-3)

    VS

    Detroit Lions

    October 17, 1:00 p.m. ET


    Joe Burrow played a great game against Aaron Rodgers, but it wasn’t enough. The Cincinnati Bengals lost and fell to 3-2, however, they remain a solid wild card contender. Burrow went to the hospital after the game due to a throat condition, but he’s fine.
    Who’s not fine is RB Joe Mixon, at least not at 100%. He played against the Packers, but Samaje Perine finished with more rushing attempts. His ankle is really bothering him, and they should be careful.
    The Detroit Lions (0-5) suffered another last-minute defeat in Week 5. Head coach Dan Campbell even cried during the post-game conference. I can understand him, they could perfectly be 2-3.
    RB D’Andre Swift keeps accumulating good performances. He has become a reliable weapon, but Jamaal Williams isn’t ready to lose the starting job race just yet.
    Playing at home should motivate them to beat the Bengals. However, they’re 0-6 SU in their last six home games.

  • Green Bay Packers (-4½)

    VS

    Chicago Bears

    October 17, 1:00 p.m. ET


    The good ol’ rivalry between the Green Packers vs Chicago Bears will have a new chapter written in Week 6.
    After losing their opener, the Packers won four straight and lead the NFC North. Aaron Rodgers and Davante Adams remain one of the best attacking duos in the league. Besides them, Aaron Jones and Randall Cobb have had a great start to the season.
    Defensively, the coaching staff made some adjustments and they allowed 22 points or less in three of their last four games.
    Chicago isn’t better than Green Bay, but they’re right behind them. Rookie QB Justin Fields played a decent game in Week 5, allowing him to regain confidence for what’s next. With RB David Montgomery out due to injury, Khalil Herbert and Damien Williams took over. They combined for 139 yards and one touchdown.
    Khalil Mack seems to be back to his usual form. He leads the team with five sacks and is aiming for the Defensive Player of the Year award.
    Expect a fierce battle. The total has gone over in 10 of their last 15 meetings.

  • Los Angeles Chargers

    VS

    Baltimore Ravens (-3½)

    October 17, 1:00 p.m. ET


    I know it’s not allowed yet, but Los Angeles Chargers vs Baltimore Ravens should have been flexed to Sunday Night. Justin Herbert and Lamar Jackson are on fire and both teams are 4-1, what else can you ask for?
    Herbert led the Chargers to a huge victory over Cleveland in Week 5. He finished with 427 total yards and five total touchdowns. Mike Williams keeps raising his hand to be recognized as the team’s No. 1 receiver. Meanwhile, Austin Ekeler keeps proving he’s an elite running back.
    The defense allowed 42 points, but that was the first time they allowed more than 24 points. Stop doubting them, they’re a real contender.
    Jackson also had a career day against the Colts after throwing for 442 yards and four touchdowns. He added 62 yards through the ground. If he can keep throwing like that, they’re gonna be a real menace each week.
    Mark Andrews keeps raising his hand to be recognized as one of the best tight ends in the league. The Ravens just need to figure out the backfield. They’ve Latavius Murray, Tyson Williams, Devonta Freeman, and Le’Veon Bell. Something good must come from it, right?
    Expect fireworks. The total has gone over in five of Baltimore’s last seven games played in Week 6. Also, we’re talking about two very explosive offenses.

  • Minnesota Vikings

    VS

    Carolina Panthers (-1)

    October 17, 1:00 p.m. ET


    Dalvin Cook is one of the best RB’s in the league. However, the Minnesota Vikings figured out how to win without him. Alexander Mattison has done a great job subbing in for him. Also, Justin Jefferson and Adam Thielen remain one of the best one-two punch receivers in the league.
    Don’t get me wrong, Cook should be the starter once healthy, but they need him at 100%. They can’t afford to lose him indefinitely.
    The Carolina Panthers (3-2) are in a similar situation. Christian McCaffrey has been out the last couple of weeks, but he’s expected to be back soon. If both McCaffrey and Cook play, this Vikings vs Panthers duel will be a blast. If not, we’ll have to settle for Kirk Cousins vs Sam Darnold.
    The total has gone over in four of Carolina’s last five games against Minnesota. Expect that trend to continue.

  • Arizona Cardinals

    VS

    Cleveland Browns (-2½)

    October 17, 1:00 p.m. ET


    The Arizona Cardinals (5-0) are the only unbeaten team left. They suffered more than expected against the 49ers in Week 5, but that’s how divisional games are.
    Kyler Murray keeps playing at a great level, and now he has more weapons than ever. Besides DeAndre Hopkins, he also has Rondale Moore, Christian Kirk, Maxx Williams, and A.J. Green. Defensively, Chandler Jones and Budda Baker have had a great start to the season.
    For good or bad, the Cleveland Browns (3-2) keep rewriting history. They became the first team in history to lose a game despite finishing with 500+ total yards, five touchdowns and zero turnovers.
    Nick Chubb and Kareem Hunt have become a two-headed monster who lives in the backfield. They can carry the load any given Sunday. Baker Mayfield hasn’t done a bad job, but he’s more inconsistent.
    I expect Cardinals vs Browns to be a high scoring game. The total has gone over in four of Cleveland’s last six games against Arizona.

  • Las Vegas Raiders

    VS

    Denver Broncos (-3)

    October 17, 4:25 p.m. ET


    The Jon Gruden era is over. The now former Las Vegas Raiders (3-2) head coach quit after an email scandal. He told the press he didn’t want to be a distraction for the team, and now Rich Bisaccia will be in charge.
    Bisaccia’s first test will be a tough one. The Raiders will visit Mile High to face the Denver Broncos (3-2), who can’t afford to lose three straight games. The Raiders have enough talent to remain competitive, but all these changes could affect their confidence.
    After winning their first three games, the Broncos are falling apart. They lost to the Steelers in Week 5, a game they could have won. The good news is that Teddy Bridgewater is fine, and he should remain the starter. Also, Courtland Sutton keeps regaining confidence each week. If he’s 100% healthy he’s a real threat.
    The Raiders are 3-8 ATS in their last 11 games. On the other hand, the Broncos are 2-6 SU in their last eight games against divisional rivals. Expect a close one.

  • New York Giants (-7)

    VS

    Dallas Cowboys

    October 17, 4:25 p.m. ET


    The day in which the Dallas Cowboys are favorites over the New England Patriots has come. They deserve to be the favorites after starting the season 4-1. Dak Prescott, Ezequiel Elliott, CeeDee Lamb, and Amari Cooper are on fire!
    Defensively, Trevon Diggs leads the league in interceptions with six. That’s right, head coach Mike McCarthy has done a great job balancing the team’s effort. The Cowboys average 34 points per game, while they allowed 23.4 points per game.
    Mac Jones hasn’t had the start everyone in New England (2-3) was hoping for, but he has done a decent job. The AFC East now belongs to the Bills, but the Patriots are still above the Dolphins and the Jets.
    RB Damien Harris is listed as day-to-day with chest injury. If he’s not able to play, expect Rhamondre Stevenson to take the lead in the back.
    The Cowboys are 3-10 SU in their last 13 games on the road. They should win this one though.

  • Seattle Seahawks (-4½)

    VS

    Pittsburgh Steelers

    October 17, 8:20 p.m. ET


    No Russell Wilson, no party. The Seattle Seahawks vs Pittsburgh Steelers will be the first game Wilson misses due to injury. He’s expected to miss several weeks, which means Geno Smith will now be under center.
    Smith should take this opportunity very seriously, but the offense should run through Chris Carson. That’s if he’s able to return, if not, they’ll be in serious trouble.
    The Steelers also lost one player for several weeks, Juju Smith-Schuster. The thing is that the receiver wasn’t making any difference on the field. The offense should be fine with Diontae Johnson, Chase Claypool, and Najee Harris carrying the load.
    Ben Roethlisberger seems tired, but he’s good enough to keep the team competitive, especially in games like these. The defense, led by T.J. Watt needs to step up and contribute a lot more.
    The Steelers are 7-3 SU in their last 10 games when playing at home against Seattle.

  • Buffalo Bills (-5½)

    VS

    Tennessee Titans

    October 18, 8:15 p.m. ET


    Josh Allen and the Buffalo Bills (4-1) are the new favorites to win the AFC. And if they keep playing like they’ve, soon they’ll become the favorites to win the Super Bowl.
    Buffalo is a very well-balanced team. Offensively, Allen is having a lot of fun with Dawson Knox, Stefon Diggs, and Emmanuel Sanders. Defensively, they just made Patrick Mahomes look really bad. That’s how good they are.
    They’ll collide with an inconsistent Tennessee Titans team. The Titans should be thankful for being in the AFC South. They lead the division with a 3-2 record and all the other teams have a losing record.
    Derrick Henry remains the heart and soul of this team. He’s pretty much unstoppable. Julio Jones and A.J. Brown have been battling with injuries. Brown came back last week, but it was like he hadn’t.
    The Bills are 4-9 SU in their last 13 games against Tennessee. However, this time only 3% of the bettors believe the Titans will pull off the upset.

NFL Week 6 News

Our NFL news page has all the NFL Week 6 content you could want. That’s right, you will be able to find the latest team, player and NFL News, stats, injury & weather reports, highlights and betting trends for every team right before you head to the NFL Week 6 odds to place your ticket!

NFL Week 6 Picks

After an in-depth analysis of the NFL Week 6 betting lines alongside the latest NFL Week 6 News, our panel of experts share their betting predictions for every NFL Week 6 matchup.  

MLB Picks, Predictions & Betting Odds

NFL Season Betting Strategy | Fail to Plan, Plan to Fail

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