Bills vs Chiefs Betting Analysis: KC WRs, RBs Must Step Up
- Stay locked in at the BetUS Sportsbook for the best Bills vs Chiefs odds.
- We’re taking a look at the key matchups for the AFC Championship Game.
- The Bills’ passing offense could take advantage of the Chiefs defense.
If you woke up just in time for the playoffs, it might seem like business as usual when you see the Kansas City Chiefs hosting the Buffalo Bills in the AFC Championship Game. Before you make your NFL football picks, there are some things to consider about this postseason’s edition of the rivalry matchup.

The Chiefs, Commanders, and Eagles look to add to their tally while the Bills seek their first Super Bowl win 🍿 pic.twitter.com/YnmVVG9OSr
— FOX Sports: NFL (@NFLonFOX) January 22, 2025
Josh Allen did more with less this season as the Bills offense lost several key weapons last offseason. Patrick Mahomes continues to do the same despite the additions of DeAndre Hopkins and rookie Xavier Worthy.
Here are the key matchups to watch in the AFC Championship Game.
Bills vs Chiefs: 3 Matchups to Watch in AFC Title Game
1. Can Mahomes, Meh Playmakers Exploit Bills Passing D?
Stop me if you’ve heard this before. The Chiefs need to improve their group of weapons for Mahomes.
Yet, every NFL playoffs, it never seems to matter. Credit Kansas City for trading for Hopkins. The former Pro Bowler had zero catches against the Texans in the Divisional Round, but it is hard to imagine Hopkins not playing a factor in the postseason at some point.
Mahomes also now has a new X-factor in Worthy, who the Chiefs can line up all over the field. Against the Texans, it was the Travis Kelce show as T-Swift’s favorite tight end posted seven receptions for 117 yards and a touchdown.
The Bills-Chiefs ending in the 2021 Divisional Round will never get old. #NFLPlayoffs pic.twitter.com/U54yNhMtmN
— NFL (@NFL) January 16, 2025
Buffalo’s passing defense ranked No. 24 during the regular season, allowing 226.1 yards per game, per NFL betting trends. This could be an area that the Chiefs can exploit.
The Mahomes cheat code is real, and the Chiefs quarterback has a chance to punish Buffalo’s defense, even if the team’s weapons are not elite.
Something to keep in mind when you bet online.
2. Allen-Shakir Connection Huge for Buffalo
At the same time, the Bills have been able to do more with less as well. No Stefon Diggs or Gabe Davis, no problem as Allen made due with his new cast of characters.
The Bills still managed to have a top 10-passing attack despite the departures of their top two wideouts over the offseason. Khalil Shakir’s NFL betting prop of 57.5 receiving yards is something to keep an eye on at Arrowhead Stadium.
1 year ago today: the Chiefs beat the Bills in Buffalo in the Divisional Round. “Wide right.” pic.twitter.com/4wIy8GnhCc
— Farzin Vousoughian (@Farzin21) January 21, 2025
Shakir led the Bills with eight catches for 70 yards when Buffalo topped Kansas City 30-21 in November, per Bills vs Chiefs stats.
3. Will Chiefs Rushing Attack Get Untracked?
The Chiefs showed no semblance of a rushing attack against the Texans, and it did not seem to matter. Running back Isiah Pacheco is back after missing a good portion of the season with an injury.
Pacheco had just five carries for 18 yards which should be concerning for those backing the Chiefs at the BetUS Sportsbook. Kansas City did not have a running back top 45 rushing yards in the Divisional Round. Kareem Hunt led the way with 44 yards on eight carries and had 60 yards on 14 rushes at Buffalo.
Questions Of The Day
Who is favored in the AFC championship between the Bills and Chiefs?
The Chiefs are 1-point favorites versus the Bills.
What is a prop bet to target for the AFC Championship?
Keep an eye on Bills receiver Khalil Shakir, who could be poised for a big game.
Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets