49ers vs Buccaneers NFL Picks: Bet the Under, 49ers ML in Week 10 11/10
- Get my NFL Week 10 predictions for the 49ers vs Buccaneers.
- The Tampa Bay Buccaneers will be hard-pressed to snap a three-game losing streak when they host the San Francisco 49ers on Sunday.
- Tampa Bay quarterback Baker Mayfield leads the league with 23 touchdown passes.
- Get the latest 49ers vs Buccaneers odds at BetUS.
The San Francisco 49ers have yet to win back-to-back games this season, and they can break that trend as a road NFL betting favorite on Sunday against the slumping Tampa Bay Buccaneers.
The 49ers continue to have injury concerns, but they expect to get one huge piece back to their lineup this week as running back Christian McCaffrey likely makes his return. McCaffrey has not played yet this season.
This could be the week San Francisco returns to the form that took them to the Super Bowl last season, especially off a bye week and a win over Dallas. That allowed extra time for Deebo Samuel (ribs) and Jordan Mason (shoulder) to heal up. Check late NFL news for their status.
The Buccaneers have lost three straight, including an overtime defeat at Kansas City last Monday. Tampa Bay has been up and down as well, which makes it a tough call for bettors this weekend. Tread lightly.
49ers vs Buccaneers Game Information
- Game: San Francisco 49ers (4-4) vs Tampa Bay Buccaneers (4-5)
- Location: Raymond James Stadium, Tampa, Fla.
- Day/Time: Sunday, Nov. 10, 1:00 p.m. ET
- 49ers vs Buccaneers Live Stream: FOX
Make sure to check updated 49ers vs Buccaneers injuries before placing your bets.
49ers vs Buccaneers Odds and Spread
49ers vs Buccaneers Betting Trends
- San Francisco is 0-7 ATS in the last seven games following a straight up victory.
- The over is 6-0 in the Buccaneers’ past six games overall.
- The 49ers have covered the fourth-quarter spread in six of the last eight road games.
- Tampa Bay has hit the team total over in eight of its last 11 home contests.
- San Francisco has won the last three meetings and five of the past seven.
2 Things to Consider When Betting on the 49ers vs Buccaneers
1. What 49ers Team Will Show Up on Sunday?
San Francisco has to be better than this, doesn’t it? The teams the 49ers have beat this season are a combined 12-23.
The addition of McCaffrey could make a big difference, even though Mason has put up 685 yards rushing with three scores. The key to your online bet may be if either or both Samuel and fellow receiver Jauan Jennings can return
#49ers RB Christian McCaffrey is baaaaaaaccccck! He looks fit, moving well and seems like he’s ready to go.
🎥: @mattblively #FTTB @CMC_22 pic.twitter.com/NynZwZvxiy
— 49ers & NFL News 24/7 (@49ersSportsTalk) November 4, 2024
Quarterback Brock Purdy has come back to earth a bit this season with 10 TD passes and seven interceptions. The 49ers’ defense is also giving up 5.3 points per game more.
The thought is that San Francisco could be ready to roll off the rest and soul searching. Take the 49ers on the moneyline (-280), but it may be close.
Bet on San Francisco 49ers ML (-280)
2. Why Buccaneers Lose Fourth Straight
Tampa Bay actually played a very good game overall at Kansas City with a national audience watching.
However, the Buccaneers’ defense did not come through at the key moments. That has been the case during a demoralizing three-game losing streak that saw them lose top receivers Chris Godwin (out for the season) and Mike Evans to injuries. Evans won’t be back until later this month.
Quarterback Baker Mayfield (league-most 23 TD passes) did drive the team down the field late in regulation to tie Kansas City before the Chiefs ended it on the first drive of OT, 30-24. The Bucs allow 27 points per game – almost eight more than 2023.
Shout to Baker Mayfield for another bulldog performance last night – without his top THREE receivers – guy is a leader and a stud
pic.twitter.com/V156UkQpf5— John Frascella (Football) (@NFLFrascella) November 5, 2024
Tampa Bay sure isn’t a dependable sports bet to win at home, where it is 2-3. But we think the Bucs can keep it close because they can score.
Bet on the Tampa Bay Buccaneers +6 (Ev)
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49ers vs Buccaneers Best Bet: Go Under
Both teams have been much better at scoring points than stopping them this season.
They come into Week 10 fifth and sixth in the league in scoring offense (55 points combined) after both were in the top seven in scoring defense last season.
With all that, you expect us to recommend betting over 51 and adding it to your NFL picks and parlays. There is just a feeling these two teams will tighten up this week in such a crossroads game.
Both teams are desperate and perhaps a little of last year’s defense will be present. The Bucs have 25 sacks (eighth in the league) and the Niners boast 10 interceptions (tied for fourth).
Big fella Vita Vea takes down Patrick Mahomes for a sack and knocks the Chiefs out of field goal range on the opening drive. 🏈💪 #NFL #MNF pic.twitter.com/lcodFkNG4u
— The Comeback (@thecomeback) November 5, 2024
The over is a combined 12-5 for the two teams. But take under 51 points.
Bet on 49ers vs Buccaneers Under 51
Questions Of The Day
Who is the active receiver with the most catches for the Bucs?
Cade Otton. The tight end has 44 receptions and four touchdowns – three in the past two games.
Who won the last matchup in Tampa Bay?
San Francisco. The .49ers scored 25 in the second half for a 31-17 in 2019.
Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets
