Bills vs Colts Week 10 Picks: Back Buffalo -4 to Blow Past Indy, 11/10
- Find the best Bills vs Colts Week 10 odds at BetUS.
- Buffalo boasts a potent offense with Josh Allen primed for another MVP performance.
- Colts running back Jonathan Taylor could challenge the Bills’ defense as he did in 2021.
- The BetUS sportsbook’s total may be too low, as both teams could trade big plays.
When Indianapolis hosts Buffalo this Sunday, it will be like two heavyweight sluggers going toe to toe. It may not be the most efficient or polished match. But it will be wildly entertaining. So buckle up and don’t take a washroom break as this will be a “slugfest”. And we’re surprised that the odds reflect a total of 47.5. It’s going way over that with Buffalo coming out with a knockout.
😱😱😱
📺: @paramountplus pic.twitter.com/FhnmVHwfQl
— Buffalo Bills (@BuffaloBills) November 3, 2024
Bills vs Colts Game Information
- Game: Buffalo Bills (7-2), Indianapolis Colts (4-5)
- Date/Time: Sunday, Nov. 10, 1 p.m. ET
- Location: Lucas Oil Stadium, Indianapolis, IN
- Bills vs Colts Live Stream: Fubo.tv
Bills vs Colts Odds and Spread
Place your Bets On Bills vs Colts At BetUs Sportsbook!
2 Betting Picks for Bills vs Colts in Week 10
1. Bills and Colts Blow up the NFL Scores
The Bills and Colts are two of the NFL’s more prolific teams. We already know that about Buffalo. It has Josh Allen and the fourth-ranked scoring offense (28.9 per game). This team will hold up its end on the NFL lines. What we don’t know is Indianapolis. Ranked 22nd in scoring offense (20.9), Indy has had a revolving door at quarterback. Joe Flacco is likely still starting.
While the Minnesota game was a write-off, Flacco is still the Colts’ best answer at quarterback. He had a bad game. So did the likes of C.J. Stroud and Brock Purdy against the NFL’s most intense defense. Buffalo also has a solid ‘D’ but Flacco and the Colts’ offense should bounce back here.
The Bills have fixed their rushing defense but they’re still vulnerable here. Jonathan Taylor remembers. He ran for 185 yards on 32 carries and five total touchdowns against Buffalo in 2021. The Colts demolished the Bills 41-15 as seven-point underdogs. It was Buffalo’s worst loss of the season and it still finished with the top-scoring defense.
Throwback to when Jonathan Taylor racked up 204 yards and FIVE touchdowns in a single game vs the Bills🔥 pic.twitter.com/UIudSYcKgM
— King of Phinland🐬👑 (@KingOfPhinland) August 22, 2023
While it’s unlikely for Taylor to match this production, our NFL picks today reveal that he’ll lead Indy to some points. Buffalo still yields points even in blowout wins. It gave up 10 first-half points against the moribund Titans. The hapless Jets put up 20. Miami outgained Buffalo and scored 27.
The Colts scored 27, 34, and 20 in Flacco’s three games before Minnesota. The veteran QB also threw seven touchdowns versus one interception for a 102.2 passer rating. The trends identify how this game may go under like five of Buffalo’s last six road games. But we’re pushing back. Bet the over.
Bet on Bills vs Colts Over 47.5
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2. Bills Outslug Colts
While we’re touting a high-scoring back-and-forth here, we have no delusions. Buffalo will eventually run away with this game. One cannot go toe-to-toe with the Bills, especially when Josh Allen is even better than ever, and win the game. Thus, the Bills by five or more points is the right NFL game prediction here.
The Dolphins dared Josh Allen to stay patient and take the short stuff against zone all day. He complied.
This is the best version of Josh Allen because he’s so adaptable pic.twitter.com/PYTWbIerW0
— Gregg Rosenthal (@greggrosenthal) November 4, 2024
Allen should be the frontrunner for MVP. He’s thrown for 17 touchdowns against only two interceptions. His 0.8% interception rate is a career high and his 105.8 passer rating is his best since 2020. With Allen’s increased efficiency, Buffalo has a +11 turnover differential. And it’s how they rank fourth in scoring despite only being 15th in total yards.
We can’t say the same for the Colts even with Flacco. At heart, he’s still a “gunslinger” and will become more so when his team is facing a 20-point deficit. The key for Buffalo will be to remain patient and exploit Indianapolis’s mistakes. The Colts have 13 turnovers and are 0-3 when they lose the turnover battle.
The four-point spread may also seem odd but not if Buffalo “follows script” by blowing Indy out. All but two of Buffalo’s seven wins have come by six or more points. Most have been by double figures. Even against Arizona where Buffalo was outscored 17-3 to start, it rallied and nearly covered the 6.5-point spread.
The spread here is four points so unless this comes down to the wire (and it won’t), it’s Buffalo all the way.
Bet on Buffalo Bills -4 vs Indianapolis Colts
Questions Of The Day
What are Josh Allen’s odds to win MVP?
Josh Allen is tied with Lamar Jackson at +300 to win the MVP. They have the shortest odds.
What is Indianapolis’s record as a home underdog?
Indianapolis is 1-1 as a home underdog this season.
Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets
