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Go with the Steelers ATS at Home vs the Arizona Cardinals

The Arizona Cardinals head to Pittsburgh in search of their first road win but it won’t be easy with the NFL betting lines having Pittsburgh favored by 5½ points.

The current NFL point spreads has Pittsburgh favored for the seventh time in the last eight meetings with Arizona.

Go with the Steelers ATS at Home vs the Arizona Cardinals
Go with the Steelers ATS at Home vs the Arizona Cardinals

Receivers Marquise Brown and Michael Wilson, tight end Trey McBride, defensive backs Joey Blount, Antonio Hamilton, Starling Thomas and Jalen Thompson, offensive lineman Elijah Wilkinson as well as defensive lineman Kevin Strong are all questionable for Arizona.

For Pittsburgh, quarterback Kenny Pickett, safety Minkah Fitzpatrick, defensive lineman Montravius Adams and receiver Calvin Austin are questionable.

This is a stretch of three out of the next four games versus teams with losing records for the Pittsburgh Steelers.

Arizona joins Tennessee and Carolina as the only NFL teams yet to win on the road with Pittsburgh 4-2 at home. The Steelers are two games behind Baltimore in the AFC North Division with Arizona in the NFC West cellar, far back of San Francisco.

When looking at the NFL futures odds, the Pittsburgh Steelers are priced at +6000 in the odds of winning the Super Bowl with Arizona having the longest championship odds at +100000.

Cardinals Struggling To Seal the Deal

Among the many issues for Arizona is that the Cardinals are 31st among 32 teams in fourth-quarter scoring as the Cardinals are 1-4 in one-score games.

Arizona ranks near the bottom of the NFL in yards per passing attempt and passing yards per game. Keep that in mind when it comes to the Cardinals vs Steelers spreads.

The Cardinals have allowed the second-most points in the NFL and are 31st out of 32 teams in scoring defense in the fourth quarter of games.

Quarterback Kyler Murray is back but many of his top pass catchers are either out or iffy to play.

Arizona has covered against the NFL betting lines in just three of its last nine games.


Steelers Showing Signs of Life on Offense

In the first game since firing the offensive coordinator, Pittsburgh put up 421 yards of total offense with quarterback Kenny Pickett throwing for a season-high 278 yards. It was the first time in 59 games Pittsburgh topped 400 yards of total offense.

A big part of the passing offense was tight end Pat Freiermuth. After being held under 10 yards in four of the first five games that he played during an injury-plagued season, Freiermuth caught 9 of 11 targets for 120 yards while running back Najee Harris ran for 99 yards. Keep that in mind when it comes time to make NFL picks this week.

Pittsburgh has covered in 11 of its last 15 games.

Cardinals vs Steelers Head-to-Head

The last time the teams met was in 2019 when Pittsburgh was favored by 2.5 points on the road and won 23-17 as Diontae Johnson returned a punt for a touchdown and also had a touchdown catch.

The game fell under the 43½-point total as the Steelers extended their winning streak against Arizona to four games.

Cardinals vs Steelers Betting Lines

Cardinals vs Steelers Game Information

  • Game: Cardinals (2-10) vs Steelers (7-4)
  • Date/Time: Sunday, Dec. 3, 1 p.m. ET
  • Location: Acrisure Stadium, Pittsburgh, PA
  • Cardinals vs Steelers TV & Live Stream: CBS, NFL Game Pass

Cardinals vs Steelers Game Weather Conditions

Temperatures are expected to be in the mid-40s at kickoff with cloudy but dry conditions so the weather shouldn’t have much of an impact on the game’s outcome.

Cardinals vs Steelers Game Prediction

Predicted Score: Steelers 27, Cardinals 17

Worth Betting the Moneyline?

It could be worth going with the Steelers are -250 to win the game as part of a parlay. Only the most adventurous of souls would roll with Arizona at +205 to win on the road for the first time this season.

NFL Pick: Pittsburgh Steelers (-250)

Worth Betting ATS?

It has been a bit of a grind for a pair of teams led by young quarterbacks with Pittsburgh is 28th and Arizona being 29th in passing offense.

Pittsburgh is 24th in passing defense compared to Arizona ranking 15th in passing yards allowed per game.

Arizona has lost its last nine road games and the last seven against AFC teams.

Pittsburgh is 4-1 against the spread in its last five home games.

The Steelers are 3-0 at home versus Arizona dating back to 1985 and covered in each of those games.

Pittsburgh is 3-1 against the spread as a favorite with Arizona splitting its 12 games as the underdog. The Steelers have covered in both games this season as a home favorite with Arizona 2-4 as the road underdog.

NFL Pick: Pittsburgh Steelers -5½

Worth Betting on the Totals?

Six of the last nine matchups between the Cardinals and Steelers landed over the total. Neither of these teams are offensive juggernauts so tread carefully when it comes to betting the totals. The total of 40 1/2 is low enough to take a chance on the game going over.

NFL Pick: Over 40 1/2



Questions Of The Day

Which team has the better home-field advantage?

Pittsburgh has won more games at home than Arizona has won games this season.

Which team has the better coaching staff?

Pittsburgh’s Mike Tomlin has won multiple Super Bowls while the jury is still out on Arizona head coach Jonathan Gannon.


The odds and predictions in the article are based on the time of writing and publication. They may differ as to when the actual event takes place.

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