Looking for a total perspective? Or betting tips to decide whether the over or under is the best bet for your NFL picks against the total in the Divisional Round of the playoffs? Well, you’ve come to the right place.
As always, we break down the NFL matchups slated for the second round of the playoffs alongside the betting online odds as we look at the latest markets.
Read on for our breakdown of the four Divisional Round matchups on the docket, starting with Saturday’s doubleheader and concluding with Sunday Night Football between the Dallas Cowboys and San Francisco 49ers.
Let’s check the latest NFL news, stats, injury reports, and NFL lines. We’ve plenty of Vegas NFL picks for NFL Divisional Round Playoffs Games.
NFL Divisional Round Weekend
Jaguars vs Chiefs
- Saturday, 4:30 p.m. ET NBC.
The Chiefs bring the No.1 scoring offense into the Divisional Round that averaged 29.2 points per game in the regular season. They averaged 25.1 ppg at home and 27.3 ppg in their final three games.
Kansas City’s defense ranked 11th after 17 games. It includes a middling pass defense and an eighth-ranked run defense. Although they’ve allowed 21.7 ppg on average, the Chiefs made the big plays that counted and helped lift Kansas to the stellar 14-3-0 record. That said, there was a conspicuous improvement down the stretch as they allowed merely 15.7 ppg over their last three.
The Jaguars averaged 24.2 ppg during the season, but that number ticks up to 27.3 over their last three games. The improved play of Trevor Lawrence and the offense helped lift the Jaguars to the AFC South title behind an 8-2 run in their last 10 games. On the defensive side of the ball, the Jaguars conceded 21.1 ppg during the season and only 16.3 ppg in their last three.
Given all these stats, there’s every likelihood of plenty of points being scored at Arrowhead Stadium to crack this total. Whether those will be evenly distributed between them or one-sided, as the first meeting that resulted in a Chiefs’ 27-17 win, remains to be seen. But knowing everything we’re shading the over here.
Pick: Over 53 (-110)
Giants vs Eagles
- Saturday, 8:15 p.m. ET


The Philadelphia Eagles boasted one of the hottest offenses in 2022, but it fell off the tracks in the final month following Jalen Hurts’ shoulder injury. Philly’s No. 1 quarterback missed two games (Week 16 and 17) before returning for his side’s final game.
On the season, the Eagles rank third in scoring with an average of 28.1 ppg, though their last three yielded a 22 ppg average. On home turf, they averaged 26.9 ppg. The defense averaged a modest 20.2 ppg but that number ticked up to 25.3 in their last three games.
The Giants have a methodical offense that plays within itself. They rank 14th in scoring with 22 ppg for the season. However, their last three games saw them put up an average of 28.3 ppg. This includes a 38-10 win over the Indianapolis Colts in Week 17 and the 31-24 upset over the Minnesota Vikings.
The G-men’s defense ranks fourth overall and includes the 14th-ranked passing defense and the 26th-ranked run defense. On the season, they’ve conceded an average of 21.9 ppg over 17 games, but just 18.7 ppg on average in their last three.
Neither team’s quarterback has any experience at this stage of the playoffs. Hurts is only playing his second postseason game and first of 2022. Daniel Jones won his first-ever playoff game last week. There are bound to be nerves and that could lead to mistakes from both. Hurts’ form is also a big question mark, seeing as he’s played one game in almost five weeks. This is a tossup, but the over stands out as the choice NFL picks here.
Pick: Over 48 (-110)
Bengals vs Bills
- Sunday, 3 p.m. ET CBS
This game has SCORING written all over it! Josh Allen and Joe Burrow are two of the game’s best signal callers, surrounded by an enviable supporting cast of offensive players that are some of the best talents in the game. Color the world shocked if they don’t light up Orchard Park on Sunday.
The Bills were pushed to the limit by the plucky Miami Dolphins, eking out the narrow 34-31 win in the Wild Card game. The game was much closer than the NFL odds had it, and that might be a red flag. Especially for a defense that was uncharacteristically porous.
That said, it wasn’t all down to the defense. Allen’s turnovers shot his side in the foot, throwing two interceptions that helped the Dolphins gain a footing in the game.
The Bengals found themselves in a similar situation against the banged-up Baltimore Ravens, needing to work harder for the 24-17 victory than most expected. Then again, John Harbaugh’s been there and done that before, leading a heavily underrated Ravens team to Super Bowl victory 10 years ago.
By all accounts, this should be a totally different game for Burrow and Co. A freer experience against a Bills defense that showed cracks against the pass last week. It may well be a more polished game from Allen too with a spot in the AFC Championship Game on the line. It’s hard to see this game not going over the total as such.
Pick: Over 49 (-110)
Cowboys vs 49ers
- Sunday, 6:30 p.m. ET, FOX


Once again, the Dallas Cowboys bring down the curtain on another round in the playoffs. But will they be at the center of the pomp and ceremony at the end of the game?
It’s one thing to upset the Tampa Bay Buccaneers 31-14 on the road. Another to do it in San Francisco against a 49ers team that is fast becoming the vogue NFL pick to win Super Bowl LVII (Yup, you heard it!).
The Cowboys’ offense can blow hot and cold from week to week. They averaged 27.7 ppg over 17 games, but just 21.3 ppg in their last three. In Week 18, the Cowboys were left reeling by the Washington Commanders 26-6.
The 49ers are a revelation, especially since rookie Brock Purdy took over at the helm of the offense. The Niners are 6-0-0 SU and 5-1-0 ATS since Purdy’s debut while the total has cracked the over in five of their six games. Most impressively, Purdy helped lift the Niners to the 41-23 win over the Seattle Seahawks in his postseason debut. He showed no rookie nerves and did nothing that would hurt his team’s chances.
There hasn’t been a debutant like Purdy, to be fair. Yes, the Niners are a team built to win, but without level-headed and poised quarterbacking, it’s impossible to win games. The Niners averaged 27.3 ppg (fifth) over 17 games this season. However, those numbers go up to 38.7 ppg for their last three-game average and up to 29.3 ppg when playing at Levi Stadium.
The odds and predictions in the article are based on the time of writing and publication. They may differ as to when the actual event takes place.