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NFL Week 13 Best ATS Bets

Holiday Hangovers and Blues

It’s hard to imagine Week 13 topping a wild Thanksgiving Week of football that saw plenty of momentum shifts, last-gasp game-winning drives, several unexpected upsets and more. But it might actually happen.

Come to think of it, how can it not? With a pivotal AFC East clash between the Buffalo Bills and New England Patriots kicking us off and marquee matchups on Sunday’s docket, such as the AFC Championship rematch between the Kansas City Chiefs and Cincinnati Bengals and a potential Super Bowl preview between the Miami Dolphins and the San Francisco 49ers.

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Quarterback Josh Allen #17 of the Buffalo Bills - Jamie Squire / Getty Images North America

Then, there is the Game of the Week! The one that everyone’s been waiting for since the start of the season. Which game do you ask? Well, wait for it … drumroll … the Cleveland Browns vs the Houston Texans, of course. It will be the highly anticipated debut of Deshaun Watson as the Browns square up to his former team on his old stomping grounds at the NRG Stadium.

With all this and more, it’s shaping up to be a memorable week in football betting. So, with so much to talk about and cover, let’s get right to the NFL predictions for Week 13.

Let’s check the latest NFL odds, stats, injury reports, and NFL lines. We’ve plenty of Vegas NFL odds and NFL week 13 picks for you to consider.

Week 13 NFL Odds, Predictions & ATS Picks

Bills vs Patriots

Thursday, 8:15 p.m. ET, Prime

It is not at all surprising to see the Bills favored in this pivotal AFC East tilt nor the watered-down betting line. which currently sits on Bills -4 (down from an opening line of -5½). On one hand, a case could be made for a touchdown line here, at the very least. On the other hand, however, the Bills have been playing down to opponents lately. They are 3-2 straight up and merely 1-4 against the spread in their last five games. This includes Thanksgiving Day’s 28-25 win over the Detroit Lions, a game in which they failed to cover as the -9½ road favorites.

On the same day, the Patriots endured a wild Thursday Night Football showdown against the Vikings in Minnesota. Mac Jones had one of his best offensive accounts this season until he blinked, and the Patriots lost 33-26. Despite the loss, the Patriots will be buoyed for this big rivalry game. The question is, can they sustain a high level of play and keep pace with the Bills for all four quarters? Nothing less will suffice to deliver the upset over the fancied Bills.

  • Picks SU: Patriots +175
  • Picks: ATS: Patriots +4 (-110)

Steelers vs Falcons

Sunday, 1 p.m. ET, CBS

The Steelers will be looking to build on rookie Kenny Pickett’s impressive showing in the 24-17 win over the Indianapolis Colts on Monday Night Football. The good news is: They have a winnable road game against a Falcons side that has lost some of its shine in recent weeks. Marcus Mariota and Co. have only one win in their last four games, and they have failed to cover the spread in five of their last six games after starting the season with six straight covers. Most recently, the Falcons succumbed to the Commanders 19-13 and slipped to a 5-7 record.

  • Picks SU: Steelers
  • Picks: ATS: Steelers PK (-110)

Packers vs Bears

Jordan Love f the Green Bay Packers throws a pass
Jordan Love f the Green Bay Packers – Patrick McDermott/Getty Images/AFP

Sunday, 1 p.m. ET, FOX

The Packers are favored over the Bears in Week 13, even though there are question marks hanging over Aaron Rodgers’ status (thumb and rib injury) after he left the Eagles game. The Bears have their own quarterback concerns as Justin Fields continues to nurse a shoulder injury. His status is up in the air for this NFC North bout, too. Historically, the Packers have dominated the Bears in the Rodgers era. A loss this week would mark a new nadir, but it would be par for the course in what has been a campaign fraught with struggles and disappointments. If Rodgers starts, the Packers are the bet. If Jordan Love starts, it is a toss-up for our NFL picks that will depend largely on which quarterback trots out for Chicago, Fields or Trevor Siemian.

  • Picks SU: Packers -190
  • Picks: ATS: Packers -4 (-110)

Jaguars vs Lions

Sunday, 1 p.m. ET, FOX

The Jaguars delivered one of the most exhilarating come-from-behind victories in Week 12’s round of NFL betting. For about a minute, they looked like world beaters, stealing the 28-27 win right from under the Ravens’ noses. Coach Doug Pederson went for broke, calling gutsy plays, and Trevor Lawrence’s clutch performance in throwing a touchdown and converting the two-pointer for the win. One win, no matter how sensational it is, does not make a winning team all of a sudden. The Lions are not unlike the Jaguars. They are mercurial, unpredictable and exciting to watch when they light it up. But they are also a little bit more polished and established. That could be enough to tip this game in their favor.

  • Picks SU: Lions
  • Picks: ATS: Lions +1 (110)

Jets vs Vikings

Sunday, 1 p.m. ET, CBS

Mike White earned a second straight start after leading the Jets to the 31-10 win over the Chicago Bears in Week 12. Taking on the high-flying Minnesota Vikings marks a significant step up in quality and class of opponent for the 27-year-old backup. But having the formidable Jets defense in tow helps. As well, having a handy blueprint courtesy of Mac Jones and the Patriots, who torched the Vikings’ secondary last Thursday, will also help. Indeed, it might be precisely for this reason that coach Robert Saleh is again taking a punt on White, after seeing what his offense could look like when managed efficiently from the pocket. It is a long shot, but the Jets could potentially deliver the upset of the week.

  • Picks SU: Jets +135
  • Picks: ATS: Jets +3 (-110)

Commanders vs Giants

Sunday, 1 p.m. ET, FOX

Is the sky falling in New York? The overachieving, feel-good, Brian Daboll-inspired G-men story of the first half of the season appears to be running out of steam down the stretch. They have lost three of their last four games and have seen the Commanders close the gap in the table during this same period. Washington comes into MetLife Stadium riding a three-game winning streak. The stakes could not be any higher in this game.

  • Picks SU: Commanders -135
  • Picks: ATS: Giants +2½ (-110)

Titans vs Eagles

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Treylon Burks #16 of the Tennessee Titans – Rob Carr/Getty Images/AFP

Sunday, 1 p.m. ET, FOX

The A.J. Brown revenge angle dominates the narrative surrounding a game that is fundamentally a clash between two playoff contenders. Predictably, the NFC-soaring Eagles are the hefty betting online favorites, even though they have been less dominant in recent weeks. The Titans, once again, are being severely undervalued despite winning seven of their last nine games. If there is a knockback against the Titans, it is the absence of a truly signature win against a bona fide contender. They need this win to get the respect they are being (rightly or wrongly) denied thus far..

  • Picks SU: Titans +200
  • Picks: ATS: Titans +5 (-110)

Broncos vs Ravens

Sunday, 1 p.m. ET, CBS

Fourth-quarter collapses have plagued the Ravens this season and the 28-27 loss to the Jaguars last week was no exception. Fortunately, they have a get-right game against a Broncos team that boasts an anaemic offense spearheaded by the shockingly inefficient Russell Wilson.

  • Picks SU: Ravens -380
  • Picks: ATS: Ravens -9½ (-110)

Browns vs Texans

Sunday, 1 p.m. ET, CBS

Is there a scenario in which Lovie Smith’s Texans poo-poo on Deshaun Watson’s coming-out party? Yes, there is. Let’s face it, nobody knows what to expect from Watson, really. Not even the Browns. The embattled quarterback has not played a single NFL game since 2020 and he has had to deal with a lot of negative press (of his own creation) since then. The Browns have not had much time to practice with Watson, either. On top of it all, there are the fans to consider and a reception at NRG Stadium that is unlikely to be of the cheery bonhomie variety. The Texans are not great, by any stretch of the imagination. But this might be a game they will desperately want to win.

  • Picks SU: Texans +270
  • Picks: ATS: Texans +7½ (-110)

Seahawks vs Rams

Sunday, 4:05 p.m. ET, FOX

Who would have thought when the season started that the NFC West matchup between the Seattle Seahawks and the reigning Super Bowl champions in Week 13 would be a bounce-back game for the former? Hands up? Anyone? Things have gone from bad to worse in a hurry for Sean McVay, and now with injuries to Matthew Stafford and Cooper Kupp on top of everything else, he is quickly running out of ideas about how to save the Rams’ 2022 campaign.

  • Picks SU: Seahawks -350
  • Picks ATS: Seahawks -7½ (-110).

Dolphins vs 49ers

Sunday, 4:05 p.m. ET, FOX

The Dolphins are legit. Tua Tagovailoa is having the best season of his young career and the Dolphins are in the thick of the AFC playoff race. But the Niners are the kind of team that nobody wants to play. Not now. And certainly not later in the playoffs. Jimmy Garoppolo and Co are finding new ways to win with a bolstered offense while Nick Bosa and the elite D-unit are the human equivalents of a giant wrecking ball. This game might not be as close as the NFL odds would have it in the end.

  • Picks SU: Niners -190
  • Picks: ATS: Niners -4 (-110)

Chiefs vs Bengals

Sunday, 4:25 p.m. ET, CBS

Often marquee rematches will have the revenge angle trotted out, and equally as often in those, the so-called revenger falls shy of the mark. This matchup is likely an exception to that [unofficial] rule. Two words: Patrick Mahomes. There is no signal caller in the game that is better at leveling the score than Mahomes. This is not to say the Bengals are not up for the task because they are. The return of Ja’Marr Chase will bolster their offense for this AFC Championship Game rematch. However, the Chiefs are easily the team to beat in the AFC and they underpin their position with an exclamation point.

Picks SU: Chiefs -140
Picks: ATS: Chiefs -2½ (-110)

Chargers vs Raiders

Sunday, 4:25 p.m. ET, CBS

The Raiders are riding a two-game winning streak. Big Whoop! Wins at the expense of the hapless Broncos and the plucky Seahawks are not going to turn them into world-beaters all of a sudden. The Chargers overcame the Arizona Cardinals 25-24 to bounce back into the win column. While both these teams have dealt with their share of frustrations, the Chargers are in a better position than the Raiders. They beat their divisional rivals 24-19 in Week 1. They should sweep this series and advance their bid for an AFC wild-card spot.

  • Picks SU: Chargers -125
  • Picks: ATS: Chargers -1 (-110)

Colts vs Cowboys

Carson Wentz #2 of the Indianapolis Colts warms up prior to the game against the Arizona Cardinals
Carson Wentz #2 of the Indianapolis Colts – Chris Coduto/Getty Images/AFP

Sunday, 8:20 p.m. ET, NBC

In the meantime, the Indianapolis Colts are not quite the laughingstock many expected they would be with novice NFL head coach Jeff Saturday. They beat the hapless Raiders, then gave the Eagles a run for their money in a narrow 17-16 loss. More recently, they fritted away the lead in Monday night’s loss to the Steelers. The Colts are still working things out, but they should not be dismissed out of hand. In fact, this could be a trap game for the Cowboys, who have had a Jekyll-and-Hyde run over the last few weeks, oscillating between a dominant performance to just scraping by.

  • Picks SU: Cowboys -570
  • Picks: ATS: Colts +11 (-110)

Saints vs Buccaneers

Monday, 8:15 p.m. ET, ESPN

The Buccaneers lost a game they should never have lost in Cleveland while the Saints were shut out by the Niners in Week 12. It is a brand-new week for Tom Brady and Co and a get-right game against a floundering divisional opponent in primetime Monday Night Football (hi Dandy Andy). The Saints are a hot mess and Andy Dalton’s primetime record is nothing to write home about.

  • Picks SU: Buccaneers -190
  • PicksATS: Buccaneers -3½ (-110)

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