Manager Carlo Ancelotti knows Inter Milan pretty well. He coached AC Milan from 2001 to 2009. That familiar feeling could help Ancelotti and visiting Real Madrid beat Inter Milan in their 2021-22 UEFA Champions League debut on Wednesday afternoon. Inter Milan is playing a lot better than those years and deserve to be considered favorites.
Expect nothing less than a showdown in San Siro. The winner will get a lot more than three points. Let’s take a look at the latest news, stats, injury reports, and soccer odds for Inter Milan vs Real Madrid. We’ve plenty of predictions for you to consider.
Game: Inter Milan vs Real Madrid
Location: San Siro, Milan
Time: Wednesday, 3 p.m. ET
Television: beIN Sports
Live Stream: fuboTV
UEFA Champions League Betting Lines
| Team | Handicap | Moneyline | Over/Under | Team Total |
| Inter Milan | Pk -130 | +150 | 2½ -135o | 1½ +125o/-155u |
| Real Madrid | Pk +110 | +180 | 2½ +115u | 1½ +145o/-175u |
| Draw | +260 |
Head to Head
- Previous Matches: 17
- Inter Milan Victories: 7 (21 goals)
- Real Madrid Victories: 8 (25 goals)
- Draws: 2
Last season, the teams also met twice in the Champions League Group Stage. Real Madrid won both matchups, winning 3-2 at home with goals from Karim Benzema, Sergio Ramos and Rodrygo. Later, they won 2-0 at San Siro with goals from Eden Hazard and Achraf Hakimi (own goal). Inter finished that game with 10 players thanks to Arturo Vidal getting a red card (33 minutes).
Los Blancos haven’t lost to Inter since the 1998-99 season. They finished with a clean sheet in three of their last 10 meetings and failed to score only once.
Why Bet on Inter Milan?
After reclaiming the Serie A title, Inter Milan’s main objective is to win the Champions League. They started the season on the right foot despite having to adapt to a new coaching staff. They also had to adapt to a life without Romelu Lukaku, who signed with Chelsea.
Manager Simone Inzaghi has done a great job maintaining a winning mentality and discovering some new talents. They started the season with a 2-1-0 record, nine goals for and three against. Only AS Roma and Lazio have scored as many goals as Inter.
Most recently, Inter drew 2-2 to Sampdoria, but that could be because the team was thinking about Real Madrid.
Individually, Joaquin Correa and Lautaro Martinez have scored two goals each. They’ve assumed Lukaku’s responsibilities when attacking. Inter also signed Edin Dzeko to help with that. Nicolo Barella leads the team in assists with three.
When betting online, you’ve to take under consideration a lot of factors, including momentum. Inter just won the Serie A and wants to prove it truly belongs among the European elite. Last season, they couldn’t advance to the Champions League Round of 16.
They also started the season 2-1 against the spread and 3-0 over/under. People usually talk about Italian football being so defensive but Inter is quite the contrary.
Alessandro Bastoni is questionable due to injury while Stefano Sensi is out. Neither absence should weigh much. Their expected lineup is Samir Handanovic; Milan Skriniar, Stefan de Vrij, Denzel Dumfries; Matteo Darmian, Marcelo Brozovic, Hakan Calhanoglu, Ivan Perisic; Nicolo Barella, Lautaro Martinez, Edin Dzeko.
Why Bet on Real Madrid?
Real Madrid leads La Liga with a 3-1-0 record, 13 goals for and six against. That should be enough for you to include them in your soccer picks, but there’s more.
With Ancelotti back in charge, Los Blancos have become a very offensive team. No other team in La Liga has scored more goals. Individually, Benzema leads the league in scoring with five goals. He’s followed by Brazilian striker Vinicius Junior with four. We’re witnessing the beginning of a lethal duo.
“He’s doing very well. He’s playing at a very high level. He has to keep it up now. He’s full of confidence at the moment, he’s composed and keeps a cool head in front of goal,” said Ancelotti of Junior.
Los Blancos have a very good roster despite not having signed Kylian Mbappe. They did sign Eduardo Camavinga and he scored one goal in his debut, helping Real Madrid beat Celta de Vigo 5-2 last Sunday.
With Camavinga on board, Madrid’s depth at midfield is enviable. They need to improve defensively, but that should be easier once David Alaba and Ferland Mendy get completely healthy.
Alaba is expected to be back on the field but Mendy isn’t. Toni Kroos, Dani Ceballos and Gareth Bale also are out due to injury. Their expected lineup is Thibaut Courtois; Dani Carvajal, Eder Militao, Nacho, David Alaba; Federico Valverde, Casemiro, Luka Modric; Vinicius Junior, Karim Benzema, Eden Hazard.
Final Analysis, Predictions
This well could end up being a preview of the Grand Finale. Both have what it takes to reach continental glory but now it’s time to prove it on the field. Inter Milan should control ball possession, but Real Madrid can be lethal on the counter-attack.
Inter deserves to be the favorite, but Madrid loves this competition. I expect both sides to score, but the total to go under. Inter hasn’t faced a good offensive unit like the one Madrid has. Madrid hasn’t faced a good defensive unit like Inter.
Don’t forget to check the props our sportsbook is offering for this and other games to increase your winning chances. Our score prediction is offering a +500 price. I like Real Madrid to score last at +105, like they did in their previous four games.
Score Prediction: Inter Milan 1, Real Madrid 1
