Inter vs Roma Picks, Prediction for April 27: Bet on Inter (-136)
- Bet on Inter Milan to win (-136) in your Inter vs Roma picks.
- Bet on Lautaro Martinez (+140) to score on Sunday.
- Make bank with our top Serie A picks! Join with our promo code HUDDLE125.

Can Inter Milan get back to winning ways vs Roma? Read on to find the best Serie A betting odds for Inter vs Roma and my expert picks to place your wagers for the Serie A match.
Il @acmilan vince il derby ed è FINALE di #CoppaItaliaFrecciarossa 🏆🔥#InterMilan 0-3 pic.twitter.com/mtwOEx8jQP
— Lega Serie A (@SerieA) April 23, 2025
Inter vs Roma Betting Trends
- Roma are riding a five-match unbeaten streak under Claudio Ranieri.
- Four of Inter’s last five matches have featured over 2.5 goals.
- Roma have failed to keep a clean sheet in their last 11 matches vs Inter.
- Both teams have scored in six of Inter’s last seven matches.
- Four of the last five meetings between Inter and Roma have featured over 4.5 bookings.
Top 2 Inter vs Roma Picks for April 27
1. Inter Milan to win (-136)
It has been a dismal week for Simone Inzaghi’s Inter. After conceding a last-second bicycle kick to Riccardo Orsolini and losing 1-0 to Bologna, Inter, the favorite at -125 in odds to win Serie A, relinquished their advantage in the title race on account of Napoli’s 1-0 win at Monza.
With five matches remaining in the Serie A schedule, Inter sit atop the table, level on 71 points with Napoli..
They proceeded to fall to a heavy 3-0 defeat to Milan, thus missing out on a trip to the Coppa Italia Final. Having won just one of their last five matches against Italian opposition, Inter will be looking to turn around their woeful form and get back to winning ways vs Roma.
Inter have been a thorn in Roma’s side recently, winning 8 of their last 10 matches, as well as their last four encounters. They’ve opened the scoring in each of their last nine meetings with the Giallorossi, and we’re backing that trend to continue in our Serie A picks.
Claudio Ranieri has lead Roma to a 17 unbeaten run in Serie A 😳👑 pic.twitter.com/1NUaNX9e98
— OneFootball (@OneFootball) April 19, 2025
2. Lautaro Martinez to score (+140)
It’s going to take something special to beat a Roma side that has not lost in league play since Dec. 15, but we’re backing Inter to come away with their fifth straight victory vs Roma, per Serie A betting trends. And we’re backing Lautaro Martinez to come up clutch.
The reigning top scorer in Serie A, Martinez has found the back of the net in four of his previous seven matches, and all signs point to him continuing that red-hot form. The last time these two teams faced off, Martinez scored in a 1-0 victory for Inter. We’re backing him to do it again in our soccer player props.
Bet on Lautaro Martinez to score (+140)
Inter vs Roma How to Watch
- Game: Inter vs Roma
- Location: San Siro, Milan, Italy
- Day/Time: Sunday, April 27, 9:00 a.m.. ET
- Inter vs Roma Live Stream: Fubo.tv
Remember to check the latest Serie A news before placing your bets.
Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets
Questions Of The Day
Which team is likely to win?
All signs point to Inter picking up a much-needed victory ahead of their Champions League semifinal vs Barcelona.
Which player is likely to score?
We’re backing Lautaro Martinez to find the back of the net for the fourth time in six matches for Inter.