Cash: $   FP: $

San Francisco 49ers vs Los Angeles Rams

San Francisco 49ers vs Los Angeles Rams News & Picks

Expert Picks

San Francisco 49ers vs Los Angeles Rams Odds

Team Odds

Spread Totals Money-Line
San Francisco 49ers +6½ -115 44½  -110o +250
Los Angeles Rams -6½ -105 44½  -110u -300

**Odds as of 11/27**

Against the Spread (Devlin Duckett)

The injury-riddled 49ers have gotten battered in three straight games, losing by a total score of 98-57. San Francisco has been slammed by injuries all season, and is now fielding a ramshackle squad. Meanwhile, the Rams have reeled off two impressive victories in a row, against the Seahawks and Buccaneers. Los Angeles leads the NFC West, and can further distance itself from the pack with a home win here. Rams’ QB Jared Goff has thrown north of 300 yards three games in a row, and he should be able to tee off on the Niners. WRs Cooper Kupp, Robert Woods, and Josh Reynolds are killing it lately, a flashback to The Greatest Show On Turf. The Rams easily cover the seven-point spread in a revenge match against their division rivals. Rams 27, 49ers 10

Over/Under (Zack Robinson)

The San Francisco 49ers come from their bye week, but several key players (Jimmy Garoppolo, Raheem Mostert and George Kittle) remain injured.

Nick Mullens will be under center and the backfield will have Jerick McKinnon as the starter.

The 49ers average 23.8 points per game and the total has gone over in five of San Francisco’s last seven games when playing on the road against the Los Angeles Rams.

The Rams are getting better each week.

Jared Goff has developed chemistry with Cooper Kupp, Robert Woods and Josh Reynolds. The defense can be really good, mainly Aaron Donald and Jalen Ramsey.

The Rams average 24.3 points per game and the total has gone under in four of their last five games this season.

Several weeks ago, the Niners beat the Rams 24-16, but they had Garoppolo, Mostert and Kittle on the field.

Go under this time.

San Francisco 49ers vs Los Angeles Rams Rundown

Head-to-Head Stats

Betting Trends

Recent Meetings & Games

Injuries