The NFL made a triumphant return with a couple of big surprises in Week 1. Now, in addition to trying to get used to seeing Tom Brady in a Tampa Bay Buccaneers uniform, we already have Week 2 odds fully loaded for all the betting enthusiasts out there. Be sure to check em and pick your favorites!
NFL Week 2 Matchups Overview
Tom Brady and the Buccaneers are home to face the Carolina Panthers. Both teams will be looking for their first victory. The Buccaneers need this one if they don’t want to be left behind by other NFC powerhouses like the New Orleans Saints, Green Bay Packers, and Seattle Seahawks (all 1-0 and looking good).
Over in the AFC, the Kansas City Chiefs and Baltimore Ravens looked solid as a stone-cold rock. In Week 2, the Chiefs will play their first Divisional Matchup (AFC West) of the season against Los Angeles Chargers while the Ravens will face the Houston Texans.
We have you covered with the latest news, stats, info, and NFL Week 2 odds for all matchups.
NFL Games of the Week
Among other interesting details, the New England Patriots will play their first prime-time game without Tom Brady and pro football will make its debut in Las Vegas.
Without further ado, here are our BetUS Games of the Week for Week 2 of the 2020 NFL Season. All game preview odds are as of writing.
Cincinnati Bengals vs Cleveland Browns (-6)
Sept. 17, 8:20 p.m. ET
QB Joe Burrow’s NFL debut was fine. He finished with 239 total yards and one rushing touchdown (also one interception); he also led the offense to a an attempt at a field goal that would have tied the game in the Bengals’ last drive, but Randy Bullock missed.
WR A.J. Green returned and led the team in catches and receiving yards (5/51), but the best news for the Bengals is that their defense looked better and was able to keep the team in the game.
The Bengals are 8-3 in their last 11 games against the Cleveland Browns.
New season, same Browns. At least that’s what we saw in Week 1; an erratic QB Baker Mayfield, poor rushing game by Kareem Hunt and Nick Chubs, and Odell Beckham Jr. with just 3 receptions for 22 yards.
Fortunately for the Browns, this is the kind of game that they need, winnable. And they tend to be a little better at home; they are 4-1 in their last five games at FirstEnergy Stadium.
Get in-depth pre-game analysis at our Cincinnati Bengals vs Cleveland Browns matchup page, as well as the latest team & player news, stats, injury & weather reports, and NFL Week 2 Odds.
Carolina Panthers vs Tampa Bay Buccaneers (-10Ev)
Sept. 20, 1:00 p.m. ET
Both teams lost in Week 1, the Carolina Panthers at home against the Las Vegas Raiders (34-30), and the Tampa Bay Buccaneers on the road against the New Orleans Saints (34-23).
Regarding the Panthers, Christian McCaffrey carried the offense once again with 134 total yards and two touchdowns while QB Teddy Bridgewater had a quiet debut with 270 passing yards and one touchdown. The rushing defense needs to step up because they allowed the Raiders 133 yards and 3 touchdowns.
The Bucs looked okay but it’s clear that they need more chemistry between the lines. Tom Brady (239 YDS, 2 TD) suffered two interceptions (including a Pick-Six) and needs much better protection. Mike Evans (2 yards, 1 TD) and Rob Gronkowski (11 yards) were ghosts. Expect RB Leonard Fournette and LeSean McCoy to be more involved.
Get in-depth pre-game analysis at our Carolina Panthers vs Tampa Bay Buccaneers matchup page, as well as the latest team & player news, stats, injury & weather reports, and NFL Week 2 Odds.
Atlanta Falcons vs Dallas Cowboys (-4½)
Sept. 20, 1:00 p.m. ET
The trifecta of Matt Ryan (450 yards, 2 TDs), Julio Jones (157 yards), and Calvin Ridley (130 yards, 2 TDs) is one of the best in the entire league, but the Falcons need to improve their running game. Todd Gurley (56 yards, 1 TD) can solve that problem but needs more time.
If Dak Prescott wants to be an elite quarterback, he needs to improve on his 2020 debut. Ezekiel Elliott (117 total yards, 2 TDs) carried the team in Los Angeles and the Cowboys also lost TE Blake Jarwin and LB Leigton Vander Esch due to injury.
The Cowboys are 10-3 in their last 13 games at home.
Get in-depth pre-game analysis at our Atlanta Falcons vs Dallas Cowboys matchup page, as well as the latest team & player news, stats, injury & weather reports, and NFL Week 2 Odds.
Baltimore Ravens (-7Ev) vs Houston Texans
Sept. 20, 4:25 p.m. ET
The Baltimore Ravens crushed the Cleveland Browns in Week 1 (38-6) with an impressive Lamar Jackson (275 yards, 3 TDs) under center and rookie RB J.K. Dobbins (22 yards, 2 TDs) proved himself as a good fit to an already well-established offense.
Now, the Houston Texans are not the Cleveland Browns, but the Ravens are 9-2 in their last 11 games against the Texans.
Speaking of the Houston Texans, DeShaun Watson and Co. disappointed in their debut against the Kansas City Chiefs. Not because they lost, but for the way they did it.
WR Will Fuller (8 REC, 112 YDS) returned to become Deshaun Watson’s main target, but he’s not DeAndre Hopkins and the Texans need to find a way to win tough games without Hopkins, or find a new Hopkins to complement Fuller, meaning find a receiver who can attract and beat a double coverage at any time.
Get in-depth pre-game analysis at our Baltimore Ravens vs Houston Texans matchup page, as well as the latest team & player news, stats, injury & weather reports, and NFL Week 2 Odds.
New England Patriots vs Seattle Seahawks (-4)
Sept. 20, 8:20 p.m. ET
The Cam Newton era with the New England Patriots began with a victory. Clearly, the Pats’ style changed as Newton rushed for 75 yards and 2 touchdowns while Julian Edelman led the receivers with just 5 receptions and 57 yards.
What didn’t change was their solid defense. New England intercepted Ryan Fitzpatrick three times and limited the Dolphins to 278 total yards.
The Patriots are 3-7 Against the Spread (ATS) in their last 10 games against Seattle.
Russell Wilson continues to show why he’s one of the NFL’s elite quarterbacks with an impressive completion ratio (31-for-35) and Seattle surrounded him with great talents such as D.K. Metcalf, Tyler Lockett, Chris Carson, and Greg Olsen. Watch out, the Seahawks are a serious contender.
The Seahawks are 6-1 in their last 7 games played in September.
Get in-depth pre-game analysis at our New England Patriots vs Seattle Seahawks matchup page, as well as the latest team & player news, stats, injury & weather reports, and NFL Week 2 Odds.
Jacksonville Jaguars vs Tennessee Titans (-9)
Sept. 20, 1:00pm ET
The Jacksonville Jaguars surprised the entire NFL fandom with an upset against the Indianapolis Colts (27-20). QB Gardner Minshew threw for 173 yards and 3 touchdowns while the defense picked Philip Rivers twice.
RB James Robinson (3.9 yards per carry) became the starter but the Jags need to improve their running game to mix things up when needed. The Jaguars are 4-11 in their last 15 games on the road.
The Tennessee Titans won a close one against the Denver Broncos (16-14), but they remain as a solid team with Derrick Henry leading the offense. The bigger problem for the Titans is K Stephen Gostkowski who missed three field goals and one extra point.
The Titans are 6-0 in their last six games at home against the Jaguars.
Get in-depth pre-game analysis at our Jacksonville Jaguars vs Indianapolis Colts matchup page, as well as the latest team & player news, stats, injury & weather reports, and NFL Week 2 Odds.
Denver Broncos vs Pittsburgh Steelers (-7)
Sept.r 20, 1:00 p.m. ET
Ben Roethlisberger is back and so are the Pittsburgh Steelers’ playoff hopes. The Steelers beat the New York Giants with Big Ben (229 yards, 3 TDs) and WR Juju Smith-Schuster (69 yards, 2 TDs) as their leaders, and the defense picked QB Daniel Jones twice.
RB James Conner is doubtful due to an ankle injury. The total has gone over in 9 of Pittsburgh’s last 13 games against the Denver Broncos.
The Denver Broncos lost a tough one against the Titans during the last seconds. Both sides struggled mainly because of the absences of Courtland Sutton and Von Miller. Not all was bad for Denver; TE Noah Fant looked like the go-to guy.
The Broncos are 4-1 in their last 5 games against the Steelers.
Get in-depth pre-game analysis at our Denver Broncos vs Pittsburgh Steelers matchup page, as well as the latest team & player news, stats, injury & weather reports, and NFL Week 2 Odds.
Los Angeles Rams (-1½) vs Philadelphia Eagles
Sept. 20, 1:00 p.m. ET
No RB Todd Gurley for the Los Angeles Rams, no problem. RB Malcolm Brown led the way with 79 yards and 2 TDs, and the Rams were able to beat the Dallas Cowboys 20-17. WR Cooper Kupp (4 receptions, 40 yards) and TE Tyler Higbee (3 receptions, 40 yards) need to be more involved.
The Rams are 4-1-1 ATS in their last six games.
Possibly, the Philadelphia Eagles were the most disappointing team in Week 1. They lost against the Washington Football Team after having a 17-point lead and QB Carson Wentz was sacked eight times.
They missed RB Miles Sanders. RB Boston Scott carried the ball nine times for just 35 yards. The Eagles are 1-4 in their last 5 games played in Week 2.
Get in-depth pre-game analysis at our Los Angeles Rams vs Philadelphia Eagles matchup page, as well as the latest team & player news, stats, injury & weather reports, and NFL Week 2 Odds.
San Francisco 49ers (-7 Ev) vs New York Jets
Sept. 20, 1:00 p.m. ET
The San Francisco 49ers also disappointed, losing against the Arizona Cardinals at home. Once again, RB Raheem Mostert was a monster with 151 total yards and one touchdown, but QB Jimmy Garoppolo needs to be better when spreading the ball.
The defense remains one of the best, but it can’t win all the games. The 49ers are 7-2 in their last 9 games against the New York Jets.
QB Sam Darnold is not enough for the Jets to become a winning team. Their rushing game (15 total attempts in Week 1) needs to be a lot better beginning with Le’Veon Bell, who will miss this game and the next few due to injury, and receivers like Breshad Perriman and Chris Hogan more involved.
The Jets are 4-2 ATS in their last 6 games when playing as the underdog.
Get in-depth pre-game analysis at our San Francisco 49ers vs New York Jets matchup page, as well as the latest team & player news, stats, injury & weather reports, and NFL Week 2 Odds.
Buffalo Bills (-5½) vs Miami Dolphins
Sept. 20, 1:00 p.m. ET
Another divisional matchup for both teams. The Buffalo Bills beat the New York Jets (27-17) while the Miami Dolphins lost to the New England Patriots (21-11).
QB Josh Allen (312 yards, 2 TDs) looked pretty good with a supporting cast led by new WR Stefon Diggs (8 rec, 86 yards). The Bills are a balanced team and they are 5-1 in their last six games against the Miami Dolphins.
No QB Tua Tagovailoa for the Dolphins, at least not yet, but after Ryan Fitzpatrick’s performance in Week 1 (three interceptions) it might be sooner than later. The Dolphins need a dominant runner to carry the load.
The Dolphins are 4-11 in their last 15 games against an opponent from the AFC.
Get in-depth pre-game analysis at our Buffalo Bills vs Miami Dolphins matchup page, as well as the latest team & player news, stats, injury & weather reports, and NFL Week 2 Odds.
Minnesota Vikings vs Indianapolis Colts (-3)
Sept. 20, 1:00 p.m. ET
Both teams lost in disappointing games. The Minnesota Vikings lost at home against the Green Bay Packers (43-34) while the Indianapolis Colts lost on the road against the Jacksonville Jaguars (27-20).
QB Kirk Cousins (259 yards, 2 TDs, 1 INT) played well, but they need him to be great and to develop more chemistry with any receiver not named Adam Thielen (110 yards, 2 TDs). RB Dalvin Cook (50 yards, 2 TDs) remains as their primary weapon.
The total has gone over in 5 of Minnesota’s last 7 games.
Philip Rivers (362 yards, 1 TD, 2 Int) played a disappointing first game as the Indianapolis Colts QB and RB Marlon Mack is lost for the season with a torn Achilles. Rivers needs to develop more chemistry with WR T.Y. Hilton, and RB Jonathan Taylor needs to step up as their main running back.
The Colts are 11-3 in their last 14 games at home.
Get in-depth pre-game analysis at our Minnesota Vikings vs Indianapolis Colts matchup page, as well as the latest team & player news, stats, injury & weather reports, and NFL Week 2 Odds.
Detroit Lions vs Green Bay Packers (-6)
September 20, 1:00pm ET
Aaron Rodgers found his best version by throwing for 364 yards and 4 TDs while RB Aaron Jones ran for 66 yards and a TD. Offensively speaking, the Packers can be one of the best NFL teams and are 6-0 in their last six games at home.
QB Matt Stafford is back, but the Lions’ running game is not. Also, they really missed WR Kenny Golladay who remains doubtful due to injury. Head Coach Matt Patricia is known for his defensive mindset, but the Lions’ defense is not good either.
The Lions are 0-8 in their last 8 games against a team from the NFC.
Get in-depth pre-game analysis at our Detroit Lions vs Green Bay Packers matchup page, as well as the latest team & player news, stats, injury & weather reports, and NFL Week 2 Odds.
New York Giants vs Chicago Bears
Sept. 20, 1:00 p.m. ET
The New York Giants need RB Saquon Barkley to be better than 6 yards in 15 carrying attempts, and QB Daniel Jones needs to be better than two picks per game while involving more receivers when distributing the ball, TE Evan Engram for example.
The Giants are 4-2 in their last 6 games against the Chicago Bears.
Before Week 1, there was a lot of controversy in Chicago because Trubisky was appointed the starter instead of Nick Foles but Trubisky (242 yards, 3 TDs) delivered against the Lions in the final quarter. To keep winning, the Bears need to develop a better running game.
The Giants are an accessible rival, and these are the games that the Bears should win without too much trouble. The total has gone over in 4 of Chicago’s last 6 games.
Get in-depth pre-game analysis at our New York Giants vs Chicago Bears matchup page, as well as the latest team & player news, stats, injury & weather reports, and NFL Week 2 Odds.
Washington Football Team vs Arizona Cardinals (-7)
Sept. 20, 4:05 p.m. ET
Yes, the Washington Football Team won in Week 1, but the Arizona Cardinals should smash them in Week 2 after defeating the San Francisco 49ers on the road.
Dwayne Haskins threw for 178 yards and 1 TD while RB Peyton Barber became the most dangerous player on the field for the Washington Football Team with 29 yards and 2 TDs. The defense looked good, but the Cardinals are a much bigger problem than the banged-up Eagles.
Surprisingly enough, the Washington Football Team is 10-2 in the last 12 games against the Arizona Cardinals.
The Arizona Cardinals have a dual-threat QB in Kyler Murray, who finished with 321 total yards and 3 total TD against a robust 49ers defense. DeAndre Hopkins debuted with an impressive 14 receptions for 151 yards, and their defense proved to be a good one.
They should be better at home, but the Cardinals are 3-12-1 in their last 16 games in the desert.
Get in-depth pre-game analysis at our Washington Football Team vs Arizona Cardinals matchup page, as well as the latest team & player news, stats, injury & weather reports, and NFL Week 2 Odds.
Kansas City Chiefs (-9) vs. Los Angeles Chargers
Sept. 20, 4:25 p.m. ET
The Chiefs beat the Houston Texans 34-20 in Week 1 with Patrick Mahomes throwing for 211 yards and 3 TD. But that’s not all, now they also have a star rookie RB in Clyde Edwards-Helarie, who ran for 138 yards and 1 TD. The Los Angeles Chargers‘ defense is good, but not good enough to contain Mahomes and his minions.
The Chiefs are 6-1 ATS in their last 7 games against the Chargers.
Tyrod Taylor doesn’t seem like the answer for the Chargers, but HC Anthony Lynn is not ready to give rookie QB Justin Herbert a chance. Joey Bosa and the defensive unit are the best chance for the Chargers to remain competitive in games like this, but the Chiefs are not the Bengals.
The Chargers are 0-6 in their last 6 games against an opponent from the AFC West.
Get in-depth pre-game analysis at our Kansas City Chiefs vs Los Angeles Chargers matchup page, as well as the latest team & player news, stats, injury & weather reports, and NFL Week 2 Odds.
New Orleans Saints (-5½) vs Las Vegas Raiders
Sept. 21, 8:15 p.m. ET
Pro football is finally coming to Las Vegas, but the Raiders are not the favorites for this one. Offensively speaking, Drew Brees owns one of the best-supporting casts in recent years and the New Orleans Saints‘ defense (2 INT and 3 sacks against the Bucs) is also good.
RB Alvin Kamara signed a juicy extension and all previous tension is water under the bridge. The Saints are 10-0 in their last 10 games against an opponent from the AFC. The Saints likely will be without Michael Thomas, who suffered a high ankle sprain in the opener and is reported to be out a few weeks.
The Las Vegas Raiders won against the Carolina Panthers thanks to an impressive game from RB Josh Jacobs (93 yards, 3 TDs) but they need to mix things more if they want to beat better teams like the Saints. TE Darren Waller and rookie WR Henry Ruggs need to be more involved.
The total has gone under in six of the Raiders last eight games.
Get in-depth pre-game analysis at our New Orleans Saints vs Las Vegas Raiders matchup page, as well as the latest team & player news, stats, injury & weather reports, and NFL Week 2 Odds.
NFL Week 2 Picks
After an in-depth analysis of the NFL Week 2 betting lines alongside the latest NFL Week 2 news, our panel of experts share their betting predictions for all 16 NFL Week 2 matchups. Here’s the rundown.
NFL Pick’Em Week 2
During the NFL season, week after week, you can enter our Pro-Football Pick Em Free Contest to predict the point spread winner for each game. Climb the leaderboard and finish at the top to reclaim a huge Free Play alongside bragging rights with your friends!
Also, during the NFL Season, three weekly winners will receive $1,000 Free Play (1st), $250 Free Play (2nd) and $100 Free Play (3rd).
NFL Week 2 Scores
NFL Week 2 FAQs
Which NFL players were injured in Week 1?
Some of the most relevant injuries from Week 1 are:
- RB Le’Veon Bell (NY Jets)
- TE Blake Jarwin (Dallas Cowboys)
- RB Marlon Mack (Indianapolis Colts)
- LB Tremaine Edmunds (Buffalo Bills)
- WR DeVante Parker (Miami Dolphins)
- TE David Njoku (Cleveland Browns)
- CB Desmond Trufant (Detroit Lions)
Are there any teams on Bye in NFL Week 2?
No, all 32 teams will play in Week 2.
Which teams will allow fans in Week 2?
- Miami Dolphins
- Cleveland Browns
- Indianapolis Colts
- Dallas Cowboys