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Arizona Cardinals vs Buffalo Bills

Sun, Sep 08, 2024 | 1:00P EST
Point Spread Game
Arizona Cardinals
Buffalo Bills

Arizona Cardinals vs Buffalo Bills Odds NFL Week 1

Mark your calendars because the Buffalo Bills are squaring off against the Arizona Cardinals in the season opener on Sunday, September 8, 2024. The early NFL odds are showing the Bills as the favorites, and for good reason!

Last season, the Bills were on fire, closing out the regular season with five straight wins, ending with a 12-5 record. They clinched the AFC East title after a crucial victory over the Dolphins in the finale. They even won their wildcard game against Pittsburgh 31-17. However, their playoff dreams were dashed by the Chiefs in a tight 27-24 loss during the divisional round. The biggest off-season shakeup for Buffalo? Star wide receiver Stefon Diggs has taken his talents to Houston, leaving a significant void in their offensive lineup.

On the flip side, the Cardinals had a tough go last season, finishing with a 4-13 record under their new head coach, Jonathan Gannon. But there’s a silver lining! This year’s draft brought some excitement to Arizona. They snagged Marvin Harrison Jr., the dynamic wide receiver from Ohio State, with the fourth overall pick, making him the first non-quarterback selected. And they didn’t stop there—they also picked up defensive lineman Darius Robinson from Missouri with the 27th pick in the first round. So, get ready, folks! This opening game is set to be a thrilling start to the season, and if you’re into NFL football odds, you definitely want to keep an eye on this matchup!

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