Week 18 NFL Betting Guide for Rams vs 49ers Regular Season Finale
The Los Angeles Rams and San Francisco 49ers have already punched their tickets to the playoffs and don’t have much to fight over on Sunday’s regular-season finale. The Rams are coming off a slim 26-25 victory over a bad New York Giants team and eked out a win thanks to three rushing touchdowns from Kyren Williams.
Meanwhile, the 49ers clinched their spot in the playoffs back in Week 14 and look like one of the most dangerous teams in the NFL, along with the Baltimore Ravens.
Despite Christian McCaffrey and Brock Purdy being inactive for Week 18, the 49ers are still favored over the Rams with an NFL spread at -4 and moneyline odds of -205.
Rams vs 49ers Game Information
- Game: Rams (9-7) vs 49ers (12-4)
- Location: Levi’s Stadium, Santa Clara, CA
- Day/Time: Sunday, Jan 7, 4:25 p.m. ET
- Rams vs 49ers Live Stream: NFL Game Pass
The Los Angeles Rams (9-7) travel to San Francisco to face the 49ers (12-4) on Sunday at Levi’s Stadium. The game is slated to start at 4:25 p.m. ET, and you can watch it on FOX.
The 49ers are +215 favorites on our Super Bowl odds board, while the Rams are +5000 long shots.
Rams vs 49ers Odds and Spreads
Rams vs 49ers Betting Trends
- The 49ers are 5-0 against the NFL spread in their last five games as a favorite of 0.5-3.0.
- The 49ers are 5-0 ATS in their last five games as an underdog of 3.5-10.0.
- Rams are 6-1 ATS in their last seven vs. NFC West.
- Rams are 0-2-2 ATS in their last four games as a road underdog of 0.5-3.0.
- Over is 6-0 in the Rams’ last six games after allowing more than 350 total yards in their previous game.
- Over is 5-0 in the Rams’ last five games following a straight-up win.
- Over is 6-1 in 49ers last seven vs. NFC West.
- Over is 7-1 in 49ers last eight games as a home favorite of 3.5-10.0.
49ers, Rams Under 41 Points
All signs point to most of the 49ers starters, excluding CMC and Purdy, will suit and play for at least the first quarter of Sunday’s regular-season finale. The Rams are locked into a Wild Card spot, but it would make sense for them to play their starters more as they look to keep some momentum into the opening round.
While it’s hard to know what each team will do regarding personnel, playcalling, and aggressiveness later in the game, I think it’s safe to say neither will be killing themselves to try to win this game.
We will see some backup quarterbacks, and who knows how many second-stringers are taking over the bulk of snaps for their first-string counterparts? With that in mind, it feels reasonable to assume that neither team will go “all out” at any point on Sunday, leading to this game falling under the Vegas NFL betting odds total.
49ers Total Touchdowns Under 2.5 (-134) + LAR Total Touchdowns Under 2.5 (-244)
Let’s double down on the Under bet for this game by parlaying both teams’ TD totals to go Under. The 49ers are -134 to fall under 2.5 touchdowns, while the Rams are -244 to miss the mark.
In addition to Matthew Stafford, Rams’ HC Sean McVay ruled out Kyren Williams, Cooper Kupp and Aaron Donald for Sunday’s game vs. the 49ers.
— Adam Schefter (@AdamSchefter) January 3, 2024
The NFL lines for each side aren’t amazing, but combine them into a parlay, and now you’re betting with fire.
Rams vs 49ers Prediction
San Francisco 49ers 20, Los Angeles Rams 16
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