MLB Betting Odds Today: Spreads, Moneylines & Over/Under Lines
Looking for the freshest MLB odds for today’s games?
BetUS delivers live, real-time odds for every 2025 MLB game, including World Series odds as the season unfolds!
Whether you’re betting on the final score, jumping on the fast-paced action of first-inning results, or backing your favorite player with a prop bet, we’ve got you covered.
Our experts are constantly adjusting the lines based on live action and betting trends, so you always know you’re getting the most current odds for an exciting and fair wager.
Featured MLB Betting Markets:
- MLB Moneyline: Bet on which team wins, no matter the score.
- MLB Run Lines (Spreads): Wager on the spread, typically set at ±1.5 runs.
- MLB Totals (Over/Under): Predict whether total runs go over or under a set number.
- MLB First 5 Innings Bets: Shorter-duration bets focusing on the game’s early action.
- MLB Prop Bets: Bet on player, team, and game-specific outcomes.
- MLB Futures Odds: World Series winners, AL/NL Champions, and MVP odds.
MLB Futures Odds – Bet on Season-Long Markets
Want to bet beyond daily matchups? Explore our featured MLB futures odds
- World Series Winner: Bet on the team that will be crowned World Series champion at the end of the season.
- AL/NL Pennant Champions: Wager on which team will win the American League (AL) or National League (NL) pennant and advance to the World Series.
- MVP, Cy Young & Rookie of the Year: Predict the winners of MLB’s top individual awards, including Most Valuable Player (MVP), Cy Young (best pitcher), and Rookie of the Year.
- Regular Season Win Totals: Bet Over or Under on a team’s total wins over the 162-game MLB season.
This Week’s Top MLB Games to Bet on
Los Angeles Dodgers at San Diego Padres Betting Analysis
The MLB odds will likely favor the Padres at home against the Los Angeles Dodgers in a key NL West series that starts on Monday.
These teams do not like each other one bit. What is fascinating about the division is that the three teams, including the San Francisco Giants, in the tight race thrive at home and are borderline mediocre on the road.
For those who bet on the MLB, this is the start of an enormous week for the Dodgers. After this run in San Diego, they face the Giants at home over the weekend. A game to watch regarding Dodgers vs Padres MoneyLine is Tuesday. As of this writing, LA has not decided on a starter.
The Padres are going with Dylan Cease, who is 1-5. That smells like a lot of runs will be scored.
Chicago Cubs at Philadelphia Phillies Betting Analysis
Another great series between teams with major playoff hopes takes place at Citizens Bank Park in Philadelphia. The Phillies will face the NL Central-leading Chicago Cubs. Philadelphia is trying to keep pace with the New York Mets in the NL East.
The Cubs have been as great on the road as they have been at home. The Phillies have been slumping of late. The Chicago Cubs Totals odds are something sharp eyes will keep a watch on as they could find nice plays when combining the way each team has been playing.
MLB lines at BetUS should be carefully monitored to see where the Cubs are the strongest plays.
New York Yankees at Boston Red Sox Betting Analysis
Rivals meet again over the weekend as the Yankees visit Fenway Park to face the Boston Red Sox.
The teams played at Yankee Stadium over the past weekend. In a scheduling quirk, they had not faced each other until June. Fenway Park is about as hitter-friendly a ballpark as there is in the majors.
Look for the Yankees vs. Red Sox runline odds when these teams meet, and look for the games to go over. Also, look for Aaron Judge and many others to go over the Green Monster in the prop market.
MLB odds should be tight despite Boston not playing strong baseball. The BoSox always rise when they face the Yankees.
San Francisco Giants at Los Angeles Dodgers Betting Analysis
The Dodgers come home after an unfriendly stay in San Diego to face another of their rivals over the weekend. In MLB odds, the Giants have been a pleasant surprise in 2025.
They are no great shakes on the road, but none of the contenders in the NL West are. What is worth watching here is the prop market, as the Dodgers’ hitters love to light it up at home.
And remember, Yoshinobu Yamamoto has been a great pitcher for LA and should keep the Giants’ bats quiet when he is scheduled to pitch on Friday. Go under.
How to Bet on MLB Odds
The typical ways to bet on MLB games are like most team sports. There is against the spread, where a team has to win by more runs than it is favored by or lose by less than it is the underdog.
There is the moneyline where you are betting on your team to win the game. Sounds simple, right? It isn’t because odds teeter and there is no guarantee an upset won’t happen. Then there is the total where you are betting whether a game will go over or under a certain number of runs. There are many MLB games every night – and sometimes during the day – so one can do their work and find the perfect spot to make a wager on the game of their choice.
MLB Moneyline Betting: Pick the outright winner, no spreads involved. Example: If the Yankees (-140) face the Red Sox (+120), betting $140 on the Yankees wins $100 if they win, while a $100 bet on the Red Sox returns $120 if they win.
MLB Spreads (Run Lines): MLB spreads are called Run Lines, typically set at ±1.5 runs. Example: If the Dodgers -1.5 beat the Mets by 2+ runs, the bet wins. If the Mets +1.5 lose by 1 run or win outright, the bet wins.
MLB Totals (Over/Under Bets): Bet on the combined total runs of a game. Example: If the total for Cubs vs. Phillies is 8.5, an Over bet wins if 9+ runs are scored, while an Under bet wins if 8 or fewer runs are scored.
MLB Player & Game Prop Bets: Bet on specific players or game events beyond just the final score. Examples:
- Player Prop: If Aaron Judge’s total home runs line is set at 1.5, an Over bet wins if he hits 2 or more home runs, while an Under bet wins if he hits 1 or none.
- Game Prop: If a bet is on “Will the Yankees score first?”, the wager wins if the Yankees score before their opponent.
First 5 Innings Lines (F5 Bets): Bet on the outcome of the game’s first five innings, focusing on starting pitchers and early scoring. Examples:
- F5 Moneyline: If the Braves F5 Moneyline is -150 against the Cubs, the bet wins if the Braves are leading after five innings. If the score is tied or the Cubs are ahead, the bet loses.
- F5 Run Line: If the Yankees -0.5 (F5) are playing the Red Sox, the Yankees must be leading after five innings for the bet to win. If tied or lost, the bet loses.
- F5 Over/Under: If the F5 total for Dodgers vs. Phillies is 4.5, an Over bet wins if 5+ runs are scored in the first five innings, while an Under bet wins if 4 or fewer runs are scored.
MLB History & Its Impact on Betting
Major League Baseball (MLB) has been the gold standard of professional baseball since its official formation in 1903. With 162 games per season, MLB offers more betting opportunities than any other major sport.
Betting on baseball dates back to the early 20th century, evolving from simple moneyline wagers to today’s run lines, player props, and live betting markets.
Advanced statistics and analytics have made MLB odds sharper than ever, giving bettors an edge when analyzing pitching matchups, run totals, and team performance trends.
Bet Responsibly with BetUS
Thanks for joining us in the thrilling world of MLB betting! Whether you’re a die-hard New York Yankees fan, love underdog stories like the Oakland A’s, or follow powerhouse teams like the Los Angeles Dodgers, we hope our insights help you make smarter wagers.
And when you’re ready to place your bets, don’t forget to use tools like our parlay calculator to maximize your potential payouts.
Here at BetUS Sportsbook & Casino, we encourage you to bet responsibly. Only wager what you can afford to lose, and always research key factors like starting pitchers, team form, and ballpark conditions before placing your bets.
Baseball is a game of strategy; make sure your betting approach is just as sharp.
Stay informed, play smart, and enjoy every pitch, home run, and extra-inning thriller. Good luck!
