Matchup Update: San Jose State vs USC NCAA College Football odds at BetUS provide quantitative college football bettors with live moneyline, spread, total, and player prop markets. USC -35½ (-110) and related odds support precise matchup analysis by comparing BetUS prices with team performance metrics to identify positive expected value before kickoff and during live betting.
Last updated: July 2026
H3: San Jose State vs USC Betting Analysis
Lincoln Riley came to Los Angeles with a big rep, and he has not delivered close to the goods expected. Another season is here, and the Trojans catch a soft opener against San Jose State. They are 35½-point favorites on college football lines board in what is expected to be a romp.
Last season, USC led the Big Ten in offense with more than 6,000 yards. And it outscored opponents 240-121 in the second half. There is a lot to expect from QB Jayden Maiava and the offense. They should deliver. The question is whether the defense can stop anyone.