Iowa vs Iowa State

Sat, Sep 06, 2025 | 12:00P EST
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Iowa State
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Iowa State Vs. Iowa Odds College Football Week 2

The 25th-ranked University of Iowa football team hosts Iowa State in an Iowa Corn Cy-Hawk Series matchup on Saturday at 3:30 PM ET. This marks the 71st meeting between these two teams, with Iowa holding a commanding 47-23 lead since their rivalry kicked off in 1894.

The Hawkeyes have won seven of the last eight and eight of the last ten meetings over Iowa State dating back to 2013. However, the battle in Kinnick Stadium has been evenly matched in recent years, with both teams splitting the last four meetings. Iowa is 25-14 all-time against the Cyclones in Iowa City. Expect this game to go down to the wire as ten of the last 12 meetings have been decided by 10 points or less, including the last six dating back to 2017.

The Iowa State vs Iowa odds are available online to bet on any device, at any time from anywhere, and after kick-off, don’t miss out on betting this game in-play on the BetUS Live Betting platform.

Next Up: Iowa State faces Arkansas State on September 21st, and Iowa goes head-to-head versus Troy on September 14th.

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