The highest total on the Week 1 Sunday slate belongs to this matchup, with NFL odds setting the over/under at 52 — a number that signals the market expects both offenses to move the ball freely in what shapes up as one of the more pass-friendly games of opening weekend. Cincinnati comes in as the home favorite at -190 on the moneyline and -3½ on the spread, while Tampa Bay gets the points at +3½ (-110) and comes back at +163 for anyone backing the road upset.
The spread sits at a clean 3½ at even pricing on both sides, keeping this firmly within a one-score game and reflecting genuine uncertainty about the gap between these two offenses. At 52, the total stands well above the Week 1 average, making the over/under the sharpest betting angle in this game for bettors focused on pace and scoring rather than the side.
- Game: Sunday, September 13, 2026 at 1:00 PM ET
- Moneyline: Bengals -190 / Buccaneers +163
- Spread: Bengals -3½ (-110) / Buccaneers +3½ (-110)
- Total: 52 (-110 both sides)