Week 11 features an interconference matchup as the Jacksonville Jaguars travel to East Rutherford to take on the New York Giants. NFL odds have the Jaguars as -1½ points road favorites at -1½ (-110), while the Giants are listed as +1½ (-110) as the home underdog.
The total of 46½ points points to balanced scoring expectations in what projects to be one of the tighter matchups on the Week 11 schedule. Jacksonville must win by at least two points to cover the spread, while New York can cover by winning outright or losing by a single point. With little separating these two teams, this matchup shapes up as an intriguing betting option for NFL bettors looking at the spread, moneyline and total.
- Game: Sunday, November 22, 2026 at 12:00 PM ET
- Spread: Jaguars -1½ (-110) / Giants +1½ (-110)
- Total: Over 46½ (-110) / Under 46½ (-110)