Baltimore opens the 2026 season as road favorites in Indianapolis, with NFL odds giving the Ravens a clear edge despite playing away from home. The Ravens sit at -190 on the moneyline and -3½ on the spread, while the Colts get the points at +3½ (-110) and come back at +163 for anyone backing the home upset.
Being favored on the road by nearly a field goal reflects the market’s confidence in Baltimore’s roster coming into the new season, with Indianapolis viewed as a step down in overall strength at this point in the line. The total of 48 carries a slight lean toward the under, priced at -115 compared to the over at -105 — a modest signal from the market that this game may trend toward a more controlled, defense-influenced pace rather than a high-scoring opener.
- Game: Sunday, September 13, 2026 at 1:00 PM ET
- Moneyline: Ravens -190 / Colts +163
- Spread: Ravens -3½ (-110) / Colts +3½ (-110)
- Total: 48 (Over -105 / Under -115)