New England opens Week 2 as a solid home favorite against Pittsburgh, with NFL odds placing the Patriots at -4½ and the Steelers getting the points at +4½, both at standard -110 pricing. At 4½ points, the market gives New England a clear edge without treating the game as out of reach for Pittsburgh.
A spread of this size sits right at the boundary between a one-score and two-score game — the extra half-point past a field goal is meaningful, since it means a Patriots win by exactly a field goal still covers for Steelers backers. The total of 43½ at -110 both sides lands on the lower-to-middle end of the Week 2 range, pointing to an expectation of a defense-influenced, moderately paced AFC matchup rather than a high-scoring affair.
- Game: Sunday, September 20, 2026 at 1:00 PM ET
- Spread: Patriots -4½ (-110) / Steelers +4½ (-110)
- Total: 43½ (-110 both sides)
