TL;DR: The Week 2 slate may lack top 5 matchups, but bettors have plenty of action across historic rivalries, power conference showdowns, and betting lines live now at BetUS.
Lining up Week 2 college bets? Hedge or parlay with today’s NFL odds to maximize value across both slates in one spot.
Keep the football momentum rolling with live spreads, totals, and moneylines on our dedicated NFL odds page. Track moves and shop the best numbers before kickoff.
Week 2 Rivalries & Key Matchups
Week 2 of the college football season may not boast a clash of top five juggernauts, but make no mistake some of the sport’s most historic rivalries and early statement games are ready to light up the board. From traditional in state battles to powerhouse programs trying to avoid early season upsets, the Week 2 college football spreads deliver plenty of intrigue for fans and bettors alike. College Football Week 2 odds are officially live at BetUS. While Week 1 sorted contenders from pretenders, this week is about rivalries.
The Cy Hawk Trophy is up for grabs in a bitter Iowa vs Iowa State clash, with the latest NCAAF Week 2 lines showing Iowa as a 3.5 point favorite. Elsewhere, two blue bloods collide when Michigan visits Oklahoma, with the Sooners laying -4.5. Looking for more Week 2 College Football matchups? Check out the lopsided lines in Florida (-24.5) vs USF and LSU (-34.5) vs Louisiana Tech. Big numbers that test your betting nerve. These NCAA Football Betting Lines offer a look at the real separation between teams.
Betting Lines Available at BetUS
So, what’s the bottom line? Your betting options go way beyond the final score. At BetUS, you can bet on college football using a full menu of markets. Hunt for value in the main College Football Moneyline Odds and totals. Or dig deeper. Target first half lines, alternate spreads, and a huge list of game and player props for every single matchup. Explore the full board. All College Football Week 2 odds are live and ready for action. Find the best college football spreads in Week 2 and get in the game.
How to Bet on College Football at BetUS
Betting on NCAA Football is simple. Find the game you want, choose your bet type, and get in on the action. Here are the most popular ways to wager:
NCAAF Point Spreads
This is the ultimate equalizer. Bet on the favorite to win by more than the point spread (e.g., -6.5) or take the underdog to win outright or lose by less than the spread (e.g., +6.5).
NCAAF Moneylines
The purest bet in sports: simply pick the team you believe will win the game straight-up. The odds reflect the probability of victory, offering bigger payouts for underdog upsets.
NCAAF Totals (Over/Under)
Forget picking a side. Bet on the combined final score of both teams. Wager on whether the total points will go Over or Under the number set by the oddsmakers at BetUS.
