Lions Lay More Than a Touchdown at Home Against Giants
NFL odds for this Week 16 matchup have Detroit favored by 5.5 points at home against New York. The Lions are favored at home, with the Giants sitting at +5.5 (-110) on the spread as they visit Ford Field. The 5.5-point line signals oddsmakers expect Detroit to control the flow, though the half-point keeps the margin within a one-score window for Giants backers.
The total is set at 48.5 points, pointing toward a moderate-to-high scoring environment. With the Lions laying more than a field goal on their home turf and the total hovering in the upper 40s, bettors have multiple angles to consider in this Monday night primetime clash. Head to BetUS to lock in your wagers before the lines shift.
- Game: Monday, December 28, 2026 at 8:15 PM ET
- Spread: Lions -5.5 (-110) / Giants +5.5 (-110)
- Total: 48.5 (-110)
