Championship baseball means everything’s on the line and so are the best betting opportunities of October. The American League Championship Series kicks off Sunday when the Seattle Mariners travel to Toronto to face the Blue Jays. Then on Monday the National League showdown between the defending champion Los Angeles Dodgers and top-seeded Milwaukee Brewers. Four teams, two series, one goal: punch a ticket to the World Series.
Check out the latest odds to win the World Series.
MLB Championship Series Betting Markets at BetUS
The bread and butter starts here: moneylines, run lines, and totals for every ALCS and NLCS game. Whether you’re backing Seattle to upset Toronto or riding the Dodgers against Milwaukee, these markets form the foundation of Championship Series betting. BetUS posts odds the moment lineups drop, giving sharp bettors early access to value before the masses move the lines.
Beyond the basics, you’ll find alternate lines that shift run spreads and totals to match your risk tolerance. Prefer laying fewer runs at lower payouts? Done. Chasing bigger odds on longshot spreads? We’ve got those too. First five innings markets let you isolate starter performance without worrying about bullpen chaos in the late innings.
ALCS Preview: Blue Jays (1) vs. Mariners (2)
The American League pennant runs through Toronto. The top-seeded Blue Jays, fresh off dispatching their AL East rival New York Yankees, are set to host the No. 2 seed Seattle Mariners. Seattle earned its spot the hard way, outlasting the Detroit Tigers in a gritty ALDS Game 5. Game 1 is scheduled for Sunday at 8:03 p.m. ET in Toronto.
- Season Series: The Blue Jays took the regular-season series 4-2, including a three-game sweep in Seattle back in May.
- Postseason History: This is a rematch of the 2022 AL Wild Card Series, where the Mariners stunned the Blue Jays with a two-game sweep in Toronto, capped by an epic comeback from a seven-run deficit in the clincher.
Schedule:
- Game 1 (at TOR): Sunday, 8:03 p.m. ET on FOX
- Game 2 (at TOR): Monday on FOX/FS1
- Game 3 (at SEA): Wednesday on FOX/FS1
- Game 4 (at SEA): Thursday on FOX/FS1
- Game 5 (at SEA, if necessary): Oct. 17 on FOX/FS1
- Game 6 (at TOR, if necessary): Oct. 19 on FOX/FS1
- Game 7 (at TOR, if necessary): Oct. 20 on FOX/FS1
NLCS Preview: Brewers (1) vs. Dodgers (3)
In the National League, the defending champion Los Angeles Dodgers travel to Milwaukee to face the top-seeded Brewers. Los Angeles made quick work of the Philadelphia Phillies, while Milwaukee survived a tough series against the division-rival Chicago Cubs. The series kicks off Monday at 8:08 p.m. ET from Milwaukee.
- Season Series: The Brewers completely dominated the Dodgers in 2025, sweeping all six regular-season matchups and outscoring them 31-16.
- Postseason History: This is their third playoff meeting. The Dodgers have had the upper hand, winning a hard-fought seven-game NLCS in 2018 and sweeping the Brewers in the 2020 NL Wild Card Series.
Schedule:
- Game 1 (at MIL): Monday, 8:08 p.m. ET on TBS
- Game 2 (at MIL): Tuesday, 8:08 p.m. ET on TBS
- Game 3 (at LAD): Thursday on TBS
- Game 4 (at LAD): Oct. 17 on TBS
- Game 5 (at LAD, if necessary): Oct. 18 on TBS
- Game 6 (at MIL, if necessary): Oct. 20 on TBS
- Game 7 (at MIL, if necessary): Oct. 21 on TBS
Understanding Traditional Championship Series Lines
Every bettor should master the big three markets. These form the foundation of NLCS betting odds and ALCS betting lines.
- Moneylines for Championship Baseball: This is the simplest bet: who wins the game? A minus sign (-) indicates the favorite (e.g., Blue Jays -150), while a plus sign (+) denotes the underdog (e.g., Mariners +130).
- Run Lines & Point Spreads: Baseball’s version of the point spread is the run line, almost always set at 1.5 runs. The favorite must win by two or more runs (-1.5), while the underdog can lose by one run or win outright (+1.5) for your bet to cash.
- Over/Under Totals: Don’t care who wins? Bet on the game’s offensive output. Wager on whether the total combined runs scored by both teams will be over or under the number set by the sportsbook.
Advanced Betting Options for ALCS & NLCS
Ready to move beyond the basics? This is where sharp bettors find their edge.
- Alternate Run Lines Explained: If you don’t like the standard -1.5 run line, you can buy or sell runs. Think the Dodgers will win in a blowout? Bet them at -2.5 for a bigger payout. Want a safer bet on the Mariners? Take them at +2.5 with reduced odds.
- First Five Innings (F5) Markets: Isolate the starting pitching matchup by betting on just the first five innings. This popular market removes the bullpens from the equation, letting you bet on which team will have the lead after five.
- Parlay Building Opportunities: Combine multiple bets onto a single ticket for a shot at a massive payout. You can parlay the Blue Jays moneyline with the Over in the Dodgers-Brewers game, or mix in bets from other sports.
Championship Series Props: Games & Players
MLB player props and game props let you bet on micro-events within the game. This is your chance to cash in on your knowledge of specific players and game situations.
- Game Prop Variety: Bet on events like “Team to Score First,” “Will There Be a Run in the 1st Inning? (YRFI/NRFI),” or the Over/Under on total hits in the game.
- Player Performance Props: Wager on individual player stats. Think a slugger is due for a home run? There’s a line for that. You can also bet on a player’s total bases, hits, or RBIs.
- Pitcher-Specific Markets: Target the aces. Bet the Over/Under on a starting pitcher’s total strikeouts, outs recorded, or earned runs allowed.
Why BetUS Leads for Championship Series Betting
With the stakes this high, you need a sportsbook that delivers. Since 1994, BetUS has provided a trusted and reliable platform for sports bettors. We offer some of the most competitive MLB Championship Series odds and a depth of market that is second to none. Our goal is to empower you, the bettor, by giving you every possible option to make the wagers you want to make.
Mobile & Live Betting Experience
Mobile betting dominates modern sports wagering, and BetUS delivers seamless experiences across all devices. The mobile platform mirrors desktop functionality without sacrificing speed or market access. Bet from anywhere, anytime, on any device—Championship Series action doesn’t wait for you to reach a computer.
