Odds Format

NFL Week 10 Odds and Betting Lines

Must-Watch Games — NFL Week 10 (2025) & Betting Angles

Thursday Night Football

Las Vegas Raiders @ Denver Broncos
Thu., Nov 6 — 8:15 p.m. ET (Prime Video)

  • Opening NFL odds make Denver a 9-point chalk (–9) with a –500 moneyline and a 43-point over/under.
  • Raiders backers can tease Las Vegas up to +12 or chase the +378 underdog price in a same-game parlay tied to the under.
  • Broncos bettors worried about the juice might pivot to an alternate spread (–10.5) at plus money or anchor Denver’s ML in a multi-leg round-robin.
  • Look for player-prop ladders on Courtland Sutton receiving yards and Aidan O’Connell passing TDs, plus sack props on Maxx Crosby to juice the handle.

International Series — Berlin (Olympiastadion)

Atlanta Falcons vs. Indianapolis Colts
Sun., Nov 9 — 9:30 a.m. ET (NFL Network)

  • NFL odds list Indianapolis as a 6.5-point favorite with a –300 ML; total opens at 48.
  • Colts supporters can buy to +6.5 for insurance or pair Indy’s ML with the over in a same-game parlay.
  • Falcons believers get +250 and could tease the Colts up to +8; combining the dog spread with the under combats overseas variance.
  • Expect heavy action on anytime-TD props for Anthony Richardson and Bijan Robinson, plus rushing-yard ladders that move quickly once limits rise.

Early Sunday Spotlight

Buffalo Bills @ Miami Dolphins
Sun., Nov 9 — 1:00 p.m. ET (CBS/Paramount+)

  • Consensus NFL odds post Buffalo –9.5 (–500 ML) with a 50-point over/under—Week 10’s highest total.
  • Dolphins backers get +395 on the ML or can pair Miami +9.5 with the over in a same-game parlay for an outsized return.
  • Look for Tyreek Hill receiving-yard “ladder” markets and Josh Allen rushing-TD props to dominate prop tickets; the outcome will swing AFC East futures.

Sunday Night Football

Pittsburgh Steelers @ Los Angeles Chargers
Sun., Nov 9 — 8:20 p.m. ET (NBC/Peacock)

  • Prime-time NFL odds make L.A. a 3-point chalk (–3) with a –150 ML and a 45-point total.
  • Steelers believers can tease Pittsburgh up to +10 or sprinkle the +129 underdog ML, banking on a T.J. Watt strip-sack to flip momentum.
  • Chargers bettors disliking the juice may attack an alternate spread (–6.5) at plus money or anchor Justin Herbert’s ML in a weekend parlay.
  • Player-prop focus: Herbert passing yards, George Pickens anytime-TD, and Watt sack props—all likely to move as kick-off nears.

Monday Night Football

Philadelphia Eagles @ Green Bay Packers
Mon., Nov 10 — 8:15 p.m. ET (ABC/ESPN)

  • Opening NFL odds install Green Bay as a 2-point favorite (–2) with a –135 ML; total sits at 44.5 amid Lambeau cold-weather risk.
  • Packers backers who dislike the juice can shift to an alternate line (–8.5) at plus odds or anchor GB’s ML in a multi-leg teaser.
  • Eagles supporters may grab +5 or chase a +115 upset, folding Eagles’ +5 into a same-game parlay tied to the under for a bigger payoff.
  • Expect robust prop menus on Jalen Hurts’ “anytime-TD,” Jordan Love passing-yard ladders, and defensive INT specials; the result will ripple through NFC bye-week futures.

NFL Week 10 Schedule & How To Watch

Thursday, November 6th, 2025

Las Vegas Raiders @ Denver Broncos- 8:15 p.m.- Prime Video

Sunday, November 9th, 2025

  • Atlanta Falcons vs Indianapolis Colts (Berlin) – 9:30 a.m. – NFL Network
  • Jacksonville Jaguars @ Houston Texans – 1:00 p.m. – CBS / Paramount+
  • Buffalo Bills @ Miami Dolphins – 1:00 p.m. – CBS / Paramount+
  • New England Patriots @ Tampa Bay Buccaneers – 1:00 p.m. – CBS / Paramount+
  • Cleveland Browns @ New York Jets – 1:00 p.m. – CBS / Paramount+
  • New York Giants @ Chicago Bears – 1:00 p.m. – FOX / Fox Sports App
  • New Orleans Saints @ Carolina Panthers – 1:00 p.m. – FOX / Fox Sports App
  • Baltimore Ravens @ Minnesota Vikings – 1:00 p.m. – FOX / Fox Sports App
  • Arizona Cardinals @ Seattle Seahawks – 4:05 p.m. – CBS
  • Los Angeles Rams @ San Francisco 49ers – 4:25 p.m. – FOX
  • Detroit Lions @ Washington Commanders – 4:25 p.m. – FOX

Sunday Night, November 9th

Pittsburgh Steelers @ Los Angeles Chargers – 8:20 p.m. – NBC / Peacock

Monday, November 10th 2025

Philadelphia Eagles @ Green Bay Packers – 8:15 p.m. – ABC / ESPN

How to watch NFL Week 10 2025

Thursday Night Football: Exclusively on Prime Video (subscription required).

International Game (Berlin, 9:30 a.m. ET): Live on NFL Network; available on most streaming bundles that include the channel.

Sunday Afternoon:

  • CBS games stream locally on Paramount+.
  • FOX games stream in the Fox Sports app (TV-provider login) and on the upcoming Fox One service in supported markets.
  • Sunday Night Football: Broadcast on NBC and streams nationwide on Peacock.
  • Monday Night Football: Simulcast on ABC and ESPN; both networks stream in the ESPN app for authenticated users.
  • Cord-cutting bundles: YouTube TV, Fubo, Hulu + Live TV, and DirecTV Stream all carry CBS, FOX, NBC, ABC, and ESPN.

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