Must-Watch Games — NFL Week 6 (2025) & Betting Angles
Thursday Night Football:
Philadelphia Eagles @ New York Giants
Thu., Oct 9 — 8:15 p.m. ET (Prime Video)
- Opening NFL odds tag Philadelphia a 7.5-point chalk (–7.5) with a –380 moneyline and a 407.5-point over/under.
- Eagles bettors who distrust the late hook can buy to –7.5 or drop Philly into a six-point teaser with another favorite.
- Giants supporters get +308 straight-up or can pair Big Blue +4 with the under in a same-game parlay for a juicier return.
- Expect a robust prop menu: Jalen Hurts “anytime-TD,” Saquon Barkley rushing ladders, and sack totals on Wink Martindale’s blitz-happy unit. The result will ripple through NFC East futures before the weekend arrives.
International Series (Tottenham Hotspur Stadium):
Denver Broncos vs. New York Jets
Sun., Oct 12 — 9:30 a.m. ET (NFL Network)
- Neutral-site NFL odds make the Broncos a 7-point favorite with a –385 ML and a 43.5-point total.
- Early-riser bettors can tease Denver down to a pick’em or grab New York +7 in a two-team teaser for “breakfast football.”
- Look for player props on Sauce Gardner interceptions and Breece Hall rushing yards to drive the overseas handle; the winner gains a key AFC wild-card tiebreaker.
Sunday Night Football:
Detroit Lions @ Kansas City Chiefs
Sun., Oct 12 — 8:20 p.m. ET (NBC/Peacock)
- Consensus NFL odds list Kansas City a 2-point chalk (–2) with a –140 moneyline; the over/under opens at 52 in anticipation of another shoot-out.
- Chiefs bettors who hate the juice may pivot to an alternate spread (–4.5) at plus money or anchor K.C.’s ML in a weekend round-robin.
- Lions believers can tease Detroit up to +11 or pair a Jared Goff upset (+120 ML) with the over in a same-game parlay for a hefty payout.
- Expect “yardage ladder” props on Patrick Mahomes and Amon-Ra St. Brown, plus anytime-TD markets on Travis Kelce, each capable of moving lines before kickoff.
Monday Night Double-Header:
Early (7:15 p.m. ET, ESPN)
Chicago Bears @ Washington Commanders
- NFL odds sit near a pick’em (Commanders –4.5) with a 50-point total. Bears backers can grab +4.5 or sprinkle the slight plus-money ML.
- Commanders bettors may buy a half-point to (–5) at plus odds.
- Rookie-QB props (Caleb Williams passing yards, Jayden Daniels rushing TDs) should command a healthy handle.
Late (8:15 p.m. ET, ABC)
Buffalo Bills @ Atlanta Falcons
- Bills open as 3.5-point road chalk (–3.5) with a –195 ML and a 48.5-point total. Falcons supporters can tease Atlanta up to +9 or chase the +167 underdog price.
- Buffalo bettors might attack an alternate spread (–4.5) at plus money, trusting Josh Allen to silence Mercedes-Benz Stadium.
- Live-bettors can hunt a middle if the total fluctuates after early possessions.
NFL Week 6 Schedule & How To Watch
NFL Week 6 includes the year’s third international game (Tottenham, London) plus a Monday-night double-header. Houston and Minnesota are on bye.
*All times Eastern
Thursday, October 9th, 2025
- Philadelphia Eagles at New York Giants – 8:15 p.m. – Prime Video
Sunday October 10th, 2025
- Denver Broncos vs. New York Jets – London (Tottenham Hotspur Stadium) – 9:30 a.m. – NFL Network
Sunday, 1 p.m. window
- Cleveland Browns at Pittsburgh Steelers – 1:00 p.m. – CBS
- Los Angeles Chargers at Miami Dolphins – 1:00 p.m. – CBS / Paramount+
- San Francisco 49ers at Tampa Bay Buccaneers – 1:00 p.m. – CBS
- Seattle Seahawks at Jacksonville Jaguars – 1:00 p.m. – Fox
- Dallas Cowboys at Carolina Panthers – 1:00 p.m. – Fox
- Los Angeles Rams at Baltimore Ravens – 1:00 p.m. – Fox
- Arizona Cardinals at Indianapolis Colts – 1:00 p.m. – Fox
Sunday 4 p.m. window
- Tennessee Titans at Las Vegas Raiders – 4:05 p.m. – Fox
- Cincinnati Bengals at Green Bay Packers – 4:25 p.m. – CBS
- New England Patriots at New Orleans Saints – 4:25 p.m. – CBS
Sunday Night
Detroit Lions at Kansas City Chiefs – 8:20 p.m. – NBC / Peacock
Monday, October 13th, 2025 – MNF double-header
Chicago Bears at Washington Commanders – 7:15 p.m. – ESPN
Buffalo Bills at Atlanta Falcons – 8:15 p.m. – ABC
Bye week:
- Houston Texans, Minnesota Vikings.
How to Watch NFL Week 6
- Thursday Night Football: Exclusive on Prime Video (subscription required).
- London game: Live on NFL Network; streamers such as Fubo carry the channel.
Sunday afternoon:
– CBS games stream locally on Paramount+ (with SHOWTIME tier).
– Fox games stream via the Fox Sports app or providers like YouTube TV and Fubo.
- Sunday Night Football: NBC broadcast; streams on Peacock.
- Monday Night Football double-header: Early game on ESPN, late game on ABC (both available via ESPN app and most live-TV streamers).
NFL+ offers live local and primetime games on mobile, as well as NFL RedZone.
Bundled services (YouTube TV, Hulu + Live TV, Fubo, DirecTV Stream) carry CBS, FOX, NBC, ESPN, and ABC.
Check out our NFL Week 6 odds and lines now and start making your picks.
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