An intriguing AFC matchup highlights the NFL Week 3 slate as the New England Patriots travel to Jacksonville to take on the Jaguars. NFL odds have the Jaguars as 1½-point home favorites at -1½ (-105), while the Patriots are +1½ (-115) as the road underdog. The total is set at 45½ points, with both the Over and Under priced at -110.
With a spread of just 1½ points, oddsmakers expect this to be one of the most competitive games of the week. Jacksonville gets a slight edge thanks to home-field advantage, but New England is well positioned as a live underdog capable of keeping the contest close. The total of 45½ points points to a balanced matchup, where timely defensive stops and red-zone execution could ultimately determine the outcome.
- Game: Sunday, September 27, 2026 at 1:00 PM ET
- Spread: Jaguars -1½ (-105) / Patriots +1½ (-115)
- Total: 45½ (-110 both sides)