🔥 Matchweek 16 Premier League Odds and Betting Lines
Premier League odds are live for Matchweek 16, setting the stage for another thrilling weekend of English top-flight soccer. Explore up-to-date 2025–26 Premier League betting odds at BetUS, including moneylines, handicaps, goal totals, team totals, and live in‑play markets for every Matchweek 16 fixture on December 13–15.
At BetUS, soccer fans get a fast, secure, and mobile‑optimized sportsbook with competitive Premier League odds, real‑time betting updates, and trusted payouts on every wager from single bets to weekend parlays.
Saturday’s Key Premier League Fixtures
- ⚽ Chelsea vs Everton odds ➤ | Sat Dec 13 – 10:00 am EST
Moneyline: Chelsea -154, Draw +295, Everton +415 |
Total Goals: Over / Under 2.5
- ⚽ Liverpool vs Brighton odds ➤ | Sat Dec 13 – 10:00 am EST
Moneyline: Liverpool -140, Draw +310, Brighton +345 |
Total Goals: Over/Under 3
- ⚽ Arsenal vs Wolves odds ➤ | Sat Dec 13 – 3:00 pm EST
Moneyline: Arsenal -725, Draw +780, Wolves +2300 |
Total Goals: Over/Under 3
Sunday & Monday’s EPL Betting Highlights
💡 Full EPL Betting Markets at BetUS
Matchweek 16 Premier League odds deliver another high‑impact December slate, with several fixtures poised to move the board from the opening whistle to the final kick. Bettors get a mix of heavyweight favorites, live underdogs, and totals spots that suit everything from single wagers to multi‑leg parlays.
Premier League Matchweek 16 runs from December 13–15 and features five headline fixtures that stand out for betting value, handle potential, and fan interest across global markets. Chelsea vs Everton and Liverpool vs Brighton anchor Saturday’s early window, combining big‑club backing with plus‑money opportunities on dangerous underdogs.
Saturday afternoon belongs to Arsenal vs Wolves, where a strong title contender hosts one of the longest underdogs of the weekend, creating natural demand for handicaps, alternate spreads, and team‑total bets. This spot also sets up perfectly as a parlay finisher for bettors already tied into earlier kickoffs.
Sunday’s schedule highlights Crystal Palace vs Manchester City, a classic elite‑favorite vs resilient home side that invites split action between short‑price City moneylines and generous Palace double‑chance or handicap plays. With a goal line hovering between 2.5 and 3, over/under positions and both‑teams‑to‑score angles become especially attractive.
Matchweek 15 wraps on Monday,with Manchester United vs Bournemouth under the Old Trafford lights, giving bettors one more standalone primetime match to close out weekend tickets. This fixture often attracts heavy live‑betting interest, as swings in momentum and early goals can rapidly reshape Asian lines, totals, and same‑game parlays.
Whether you’re scanning Premier League odds for upset potential, comparing sharp vs public action, or building same-game parlays, BetUS provides full EPL markets all weekend long with live updates, competitive prices, and a mobile-optimized platform for every wager.
Bet on Premier League Action
Wager with EPL soccer odds that update live across moneylines, spreads, and totals. Our fast, secure, and mobile-friendly platform ensures smooth transactions and strong data protection, keeping every bet simple and reliable. Built for transparency and consistent uptime, the sportsbook makes Premier League betting seamless—so whether you’re checking Premier League title odds, browsing soccer odds, or comparing other markets, you’ll find clear pricing and easy access in just a few taps.
Don’t want to wait? No problem; you can start placing your Premier League bets once you finish reading our insights regarding all the action from last season and which teams are the favorites to win the upcoming campaign, and be ready for outstanding Live Betting as soon as play starts.
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Premier League Odds: Bet on EPL for the 2025–26 Season
To bet on the English Premier League with high success rates, it’s essential to know the most popular betting options. The action is not limited to the final score; you can also take advantage of different in-game wagers.
Moneyline
The straightforward option. You bet on Team A or Team B to win the game. You can also bet on the draw, which usually offers an excellent price.
Handicap
The handicap, also known as the spread, covers the goal difference between the favorite and the underdog. For example, if Team A is listed as -1.5, it means that Team A must win by at least two goals. So, if the match ends with a draw or with a one-goal difference, the underdog “wins.”
Totals
Here, you can disregard the Premier League soccer odds for the game because it doesn’t matter which team wins. You bet on the game’s total goals to be over or under a certain amount. If the game total is set at four goals and you bet on the over, you need the match to finish with more than four goals, regardless of how many goals each team scores. With the under, it is the opposite.
Keep in mind that if the game total is exactly four goals, the bet becomes a push, and you will receive your initial money back—no more, no less.
Prop Bets
A lot can happen while betting on the EPL. Here is where the prop bets come into play because you can wager on an event that may or may not occur. Divided into game and player props, here are some of the most popular:
- Both teams to score: bet on whether both teams will score during the game.
- Winning margin: bet on the difference by which Team A or Team B will win.
- Anytime goalscorer: bet on a specific player to score during the game.
- Player to assist: bet on a particular player to assist during the game.
- Total corners: bet on how many corners there will be in total during the match.
- First/Last team to score: bet on which team will score the first and last goal.
- To win to nil: bet on a team to win while keeping a clean sheet.
Recap of the 2024-25 Season
Before discussing the EPL soccer odds for the upcoming season and which teams are the favorites to win gold, a brief recap of the 2024-25 season can be very helpful.
Liverpool won the title with a very comfortable 10-point advantage over Arsenal. After winning four titles in a row, Manchester City finished third, followed by Chelsea and Newcastle. All five qualified for the UEFA Champions League.
Tottenham also qualified for the UCL despite finishing seventeenth. The Spurs got their ticket by winning the UEFA Europa League. Regarding the UEL, Aston Villa and Crystal Palace will represent the EPL next season.
Individually, Mohamed Salah (Liverpool) won the Golden Boot after scoring 29 goals. Erling Haaland (Manchester City), who was the favorite in the English Premier League odds before the start of the season, finished third with 22 goals.
Salah also finished with the most assists, 18, but Bruno Fernandes (Manchester United) created the most chances, with 91. That’s the only thing Manchester United managed to win.
Premier League Betting Odds to Win the 2025-26 Title
You can bet on which team will win the 2025-26 EPL title right now, literally. Before you do, take a moment to get to know each top candidate. Don’t forget to check the soccer futures frequently, as a lot can change from one week to the next. The only constant is that BetUS is the most trusted odds page for the Premier League.
Liverpool (+700)
Liverpool already had it all, but the Reds signed Florian Wirtz from Bayer Leverkusen, one of the most talented, creative midfielders in the business. Wirtz didn’t come alone because the Reds also signed Jeremie Frimpong. The final piece of the puzzle is Milo Kerkez, a talented left-back who won’t require any adaptation time, having played for Bournemouth last season. The team is also likely to get more motivation to win after the tragic passing of Diogo Jota in a car crash.
Manchester City (+450)
Manchester City keeps trusting Pep Guardiola. Who can blame them? Even after one of the worst seasons since the Spanish took over as head coach, the Citizens finished in third place.
They signed Tijjani Reijnders from AC Milan and Ryan Cherki from Lyon. Also, Rodrigo Hernandez, the current Ballon d’Or winner, will return after a long-term injury. More than enough to be atop the English Premier League outrights.
Arsenal (-225)
Arsenal hasn’t won the Premier League title since the 2003-04 season. However, you will find the Gunners among the favorites. Unlike the other top two candidates, the Gunners aren’t spending like crazy. Head coach Mikel Arteta trusts the current roster, and he is right to do so as long as they can avoid injuries. Last season, several star players suffered injuries, including Kai Havertz, Bukayo Saka, Martin Odegaard, and Gabriel Jesus, among others.
Manchester United(+2500)
Despite ups and downs, their global following and market volume keep them among the most bet-on clubs in Premier League betting markets.
Dark Horses
Believe it or not, Manchester United went from top soccer betting candidate to dark horse, especially after finishing the 2024-25 season in 15th place. The good news is that the Red Devils offer a +2800 price, which is good value considering it will be Rubem Amorim’s first complete season as the team’s head coach. Additionally, the Red Devils have a new certified scorer in Matheus Cunha.
Tottenham (+5000) has never won the English Premier League title, but the Spurs will be highly motivated after winning the UEFA Europa League, beating Manchester United in the grand finale. In addition, the Spurs made some significant signings, such as Mathys Tel and Kevin Danso, but none is more important than the new head coach, Frank Thomas, who coached Brentford for the last four seasons and finished in the top 10 twice. Having a coach who knows every single opponent well is a huge advantage.
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