MLB Betting Odds and Lines

MLB Betting Odds Today: Spreads, Moneylines & Over/Under Lines

Looking for the freshest MLB odds for today’s games? BetUS delivers live, real-time lines for every matchup.

Track updated moneylines, run lines, and totals, plus season-long World Series odds as the playoff race heats up.

Bet on inning-by-inning action, player props, or full-game results—our traders move the numbers instantly to reflect live play and betting trends.

Whether you’re swinging for home-run props or lining up Sunday parlays with the latest NFL odds, BetUS keeps every market at your fingertips.

Regular Season Down to Final Week

Milwaukee Brewers at San Diego Padres Betting Analysis

The Padres made a good run at the Dodgers, but it looks like they will come up short of winning the NL West. They won’t have it easy in the final Week of the season as the NL Central champion Milwaukee Brewers come to Petco Park. San Diego needs to finish strong here and get set up for the final series against the Diamondbacks.

Playing for a postseason position and setting up your pitching rotation for the wild-card round is key. MLB odds in the first series should favor the home team throughout, as Milwaukee is looking to lock up the No. 1 seed in the National League. Go with the Brewers to make the Padres’ lives miserable.

Chicago White Sox/Baltimore Orioles at New York Yankees Betting Analysis

The Yankees have feasted on bad teams of late. They actually have the best record in baseball over the last 45 games or so. The White Sox and Orioles are playing for absolutely nothing. The Bronx Bombers will be heavy moneyline favorites in all of these games.

Don’t be surprised if the Yankees win them all as they try to catch the Blue Jays in the AL East. The moneyline on the MLB odds at BetUS for the White Sox/Orioles against the Yankees figures to be steep. This could be a good way to parlay the Yankees, who should motor through these games.

St Louis Cardinals at Chicago Cubs Betting Analysis

The Cubs enter the final week in great shape in the NL Wild Card race. They will finish the season against the rival St. Louis Cardinals at Wrigley Field. The Cardinals are well off the pace in the National League and are just playing to mess with their opponents’ minds in the final weekend of the season.

MLB lines at BetUS are definitely worth following for these games because if the Cubs manage to lock up the top wild-card slot, they could rest some regulars. That sets up a high-scoring series, so be sure to check Cardinals vs Cubs run line odds in each game. That’s part of the fun of Wrigley Field.

Los Angeles Dodgers at Seattle Mariners Betting Analysis

The Dodgers would love to lock up the NL West before heading into the final weekend of the season. Why? Because they have to go to Seattle to play the Mariners, who are looking to outlast the Houston Astros and win the AL West. Should these games prove meaningful for Seattle and not for LA, look for Seattle to be favored on the Dodgers vs Mariners moneyline odds.

Dodgers vs Mariners totals odds should be monitored closely, depending on where each team stands in the standings. The Friday game is slated to be Clayton Kershaw against George Kirby. It would be the future Hall of Famer’s final regular-season start. Will he have his best, or will he be doing too much to impress? Try the Mariners on MLB odds.

New York Mets at Chicago Cubs Betting Analysis

The Mets are in a fight for their postseason lives. They once were 45-24 and are a shadow of the team that won that many games early in the season. They have found a way to lose every way possible – an inside-the-park home run in extra innings on Saturday – and are risky business when looking at MLB lines at BetUS.

Expect games in these series to be tight and runs to be at a premium. Go with the Cubs moneyline odds against the Mets, who are playing like they would rather go home than to the playoffs.

• MLB Moneyline: Bet on which team wins, no matter the score.
• MLB Run Lines (Spreads): Wager on the spread, typically set at ±1.5 runs.
• MLB Totals (Over/Under): Predict whether total runs go over or under a set number.
• MLB First 5 Innings Bets: Shorter-duration bets focusing on the game’s early action.
• MLB Prop Bets: Bet on player, team, and game-specific outcomes.
• MLB Futures Odds: World Series winners, AL/NL Champions, and MVP odds.

MLB Futures Odds – Bet on Season-Long Markets

Want to bet beyond daily matchups? Explore our featured MLB futures odds

• World Series Winner: Bet on the team that will be crowned World Series champion at the end of the season.
• AL/NL Pennant Champions: Wager on which team will win the American League (AL) or National League (NL) pennant and advance to the World Series.
• MVP, Cy Young & Rookie of the Year: Predict the winners of MLB’s top individual awards, including Most Valuable Player (MVP), Cy Young (best pitcher), and Rookie of the Year.
• Regular Season Win Totals:  Bet Over or Under on a team’s total wins over the 162-game MLB season.

The typical ways to bet on MLB games are like most team sports. There is against the spread, where a team has to win by more runs than it is favored by or lose by less than it is the underdog.

There is the moneyline where you are betting on your team to win the game. Sounds simple, right? It isn’t because odds teeter and there is no guarantee an upset won’t happen. Then there is the total where you are betting whether a game will go over or under a certain number of runs. There are many MLB games every night – and sometimes during the day – so one can do their work and find the perfect spot to make a wager on the game of their choice.

MLB Moneyline Betting: Pick the outright winner, no spreads involved. Example: If the Yankees (-140) face the Red Sox (+120), betting $140 on the Yankees wins $100 if they win, while a $100 bet on the Red Sox returns $120 if they win.

MLB Spreads (Run Lines): MLB spreads are called Run Lines, typically set at ±1.5 runs. Example: If the Dodgers -1.5 beat the Mets by 2+ runs, the bet wins. If the Mets +1.5 lose by 1 run or win outright, the bet wins.

MLB Totals (Over/Under Bets): Bet on the combined total runs of a game. Example: If the total for Cubs vs. Phillies is 8.5, an Over bet wins if 9+ runs are scored, while an Under bet wins if 8 or fewer runs are scored.

MLB Player & Game Prop Bets: Bet on specific players or game events beyond just the final score. Examples:

• Player Prop: If Aaron Judge’s total home runs line is set at 1.5, an Over bet wins if he hits 2 or more home runs, while an Under bet wins if he hits 1 or none.
• Game Prop: If a bet is on “Will the Yankees score first?”, the wager wins if the Yankees score before their opponent.

First 5 Innings Lines (F5 Bets): Bet on the outcome of the game’s first five innings, focusing on starting pitchers and early scoring. Examples:

• F5 Moneyline: If the Braves F5 Moneyline is -150 against the Cubs, the bet wins if the Braves are leading after five innings. If the score is tied or the Cubs are ahead, the bet loses.
• F5 Run Line:  If the Yankees -0.5 (F5) are playing the Red Sox, the Yankees must be leading after five innings for the bet to win. If tied or lost, the bet loses.
• F5 Over/Under:  If the F5 total for Dodgers vs. Phillies is 4.5, an Over bet wins if 5+ runs are scored in the first five innings, while an Under bet wins if 4 or fewer runs are scored.

MLB History & Its Impact on Betting

Major League Baseball (MLB) has been the gold standard of professional baseball since its official formation in 1903. With 162 games per season, MLB offers more betting opportunities than any other major sport.

Betting on baseball dates back to the early 20th century, evolving from simple moneyline wagers to today’s run lines, player props, and live betting markets.

Advanced statistics and analytics have made MLB odds sharper than ever, giving bettors an edge when analyzing pitching matchups, run totals, and team performance trends.

Bet Responsibly with BetUS

Thanks for joining us in the thrilling world of MLB betting! Whether you’re a die-hard New York Yankees fan, love underdog stories like the Oakland A’s, or follow powerhouse teams like the Los Angeles Dodgers, we hope our insights help you make smarter wagers.

And when you’re ready to place your bets, don’t forget to use tools like our parlay calculator to maximize your potential payouts.

Here at BetUS Sportsbook & Casino, we encourage you to bet responsibly. Only wager what you can afford to lose, and always research key factors like starting pitchers, team form, and ballpark conditions before placing your bets.

Baseball is a game of strategy; make sure your betting approach is just as sharp.

Stay informed, play smart, and enjoy every pitch, home run, and extra-inning thriller. Good luck!