Week 12 kicks off the Thanksgiving Day schedule with an NFC North divisional matchup as the Chicago Bears travel to Detroit to face the Lions. NFL odds have the Lions as -2½ points home favorites at -2½ (-110), while the Bears are listed as +2½ (-110) as the road underdog.
The total of 51½ points is one of the highest on the Week 12 board and reflects expectations for an entertaining divisional showdown. Detroit must win by at least three points to cover the spread, while Chicago can cover by winning outright or losing by two points or fewer. With a narrow spread and a high projected total on Thanksgiving Day, this matchup shapes up as an intriguing betting option for NFL bettors looking at the spread, moneyline and total.
- Game: Thursday, November 26, 2026 at 12:00 PM ET
- Spread: Lions -2½ (-110) / Bears +2½ (-110)
- Total: Over 51½ (-110) / Under 51½ (-110)