Week 10 features an AFC East divisional matchup as the Buffalo Bills travel to East Rutherford to face the New York Jets. NFL odds have the Bills as -7 pointa road favorites at -7 (-110), while the Jets are listed as +7 (-110) as the home underdog.
The total of 46½ points suggests a game with solid scoring expectations between division rivals. Buffalo must win by more than a touchdown to cover the spread, while New York can cover by winning outright or losing by seven points or fewer. With the Bills entering as sizable road favorites in this AFC East showdown, this matchup shapes up as an intriguing betting option for NFL bettors looking at the spread, moneyline and total.
- Game: Sunday, November 15, 2026 at 12:00 PM ET
- Spread: Bills -7 (-110) / Jets +7 (-110)
- Total: Over 46½ (-110) / Under 46½ (-110)