Wednesday, August 17
09:06:24 EST


Game 1st H 2nd H 1st Q 2nd Q 3rd Q 4th Q


Thu, Sep 08, 2022 EST

Point Spread
Team Total
-2½ -110
52  -110o
+2½ -110
52  -110u
Regular Season Week 1.

NFL Bills vs Rams Week 1


This match-up could be a preview of Super Bowl 57. Expect an improved Bills defense after they signed Von Miller during the off-season.

The Bills also improved a tight end by signing O. J. Howard during the off-season, which should help quarterback Josh Allen.

You can also expect Matthew Stafford from the Rams to throw around 250 passing yards without some of his top wide receivers from last season.

While he still has Cooper Kupp, he lost Robert Woods and Odell Beckham Jr. during the off-season.However, the team signed Allen Robinson during the off-season, which should help him out a little.

With both teams known to throw the ball, expect a high-scoring game with at least 500 passing yards between the two teams. Stafford and Allen will want to score every possession.

However, the Bills secondary is not as good as the Rams, meaning Stafford has the best chance to score against the Bills defense.

How do Bills vs Rams Odds Work for this Matchup?

Vegas NFL odds with the Bills vs Rams matchup are going to be tight for all the wagering options in this game.

First, gamblers need to know about the odds on the NFL point spreads. With both teams being early Super Bowl favorites, the odds will be near even no matter which team you pick on the spread.

With the strength of these two teams, you could see both teams being a pick where no points are given.

However, if the Vegas NFL odds move, you could see the Bills at +1.5 points. With the Bills at +1.5, it means if they lose by only one point, the wager on the NFL point spreads is a winner if you make that pick.

This game could be a high-scoring game, giving gamblers a reason to look into the over/under of the game. Here is another area where the Vegas NFL odds will be close to even money for gamblers. They just need to pick if the total points are over or under the number Vegas is giving the teams.

While the moneyline usually offers the best Vegas NFL odds for the underdog, this game is evenly matched.

Gamblers might find close even odds for both teams. However, the Bills might get plus odds before the game starts.

BetUS Offer

With a Super Bowl like matchup of the Bills vs Rams, comes some Super Bowl like offers from BetUS. You don’t need to have a Super Bowl ring to get the offers they have for new customers.

Any new customer that makes their first deposit with BetUS gets it matched, up to 150% the deposit amount.

These matching deposit offers can be awarded up to $2,500 the deposit amount. Customers can also get a 50% credit of their deposit added for casino wagers. So sign up with BetUS and feel like a real champion with these offers.

Bills vs Rams Prop Bets

The Bills vs Rams week one matchup could give gamblers even more things to wager on with prop bets.

Prop bets are wagers on specific things that could happen during the Bills vs Rams matchup. Some are with team performance while others can be on players.

Player props for Josh Allen and the number of passing yards could be found in the prop bets area. Another one could be one with Aaron Donald and how many sacks he will have in the game. Matt Stafford will also have a player prop that will deal with his passing stats.

Buffalo Bills Odds to win the Super Bowl +650

Los Angeles Rams Odds to win the Super Bowl +1100

HOW TO BET ON Bills vs Rams Matchup

This Bills vs Rams matchup puts two of the best teams in the NFL against each other, which makes things interesting for gamblers.

The Rams get a slight edge with this game, as they are defending Super Bowl champs and playing at home.

They also have both a good defensive front line and a good secondary with Jalen Ramsey leading that secondary.

The Vegas NFL odds could have this game as a toss-up, with both teams being Super Bowl favorites. If you find this as a toss-up, the Rams might give gamblers the best option early with their roster for this season.

However, if the NFL point spreads start moving to where the Bills have plus odds on the spread, and depending on the number of points they would get, they could be an interesting pick.

This game has all three main wagering options in play for gamblers to examine. This game could easily be as close as one point or only a three point game. So this game shouldn’t be a runaway game by either team.

The Bills made sure they worked on both offense and defense during free agency. With the players they signed, they have the key pieces they need to keep the game within striking distance. If they get anything over +3.5 points, that would be the best wager to make.

If you rather bet on the moneyline, that wager could be great for gamblers early. With the game a dead heat, you could get the Rams at great Vegas NFL odds, despite being defending Super Bowl champions. If you find them with good odds on the moneyline, they might give gamblers a glorious return in this game.

However, the Bills could also provide great return if they are listed as underdogs. Their offense can give the Rams defense some problems, meaning a moneyline wager on them winning would give a slightly better return.

The over/under could be yet another wagering option gamblers go after. With both teams having both great defenses and offenses, it’s hard to judge if this will become a shootout or a low-scoring affair.

Examining the past offensive and defensive stats of both teams can help with finding out how things will go on the over/under.

The Vegas NFL odds will shift depending on how these two teams perform during the NFL preseason. This is where gamblers can see how players do and if any of those all important players get injured during the preseason. It will also show who is on the final roster before the Bills vs Rams game starts.

That final roster will be key in this matchup. Currently, with the Bills, they added a few key players while the Rams lost a few of their talented players.

However, the Rams also kept their best players and filled the holes they had with players that left.

NFL Related Articles

Free NFL Expert Picks Los Angeles Rams Game-by-Game Predictions

“Run it back!” The Los Angeles Rams chanted repeatedly during their championship parade through Tinseltown in February as they celebrated their Su…

August 14, 2022

Free NFL Expert Picks Arizona Cardinals Game-by-Game Predictions

Even though the Arizona Cardinals are coming off a solid 11-6-0 season, they enter 2022 with an unexceptional set of expectations in the betting. The …

August 13, 2022

Free NFL Expert Picks San Francisco 49ers Game-by-Game Predictions

The San Francisco 49ers’ hype train is steaming ahead and the question marks hanging over newly minted starting quarterback Trey Lance are no ex…

August 12, 2022

NFL News CFL Week 11 Power Rankings: New Kings of the Jungle?

The Winnipeg Blue Bombers remain atop the CFL Power Rankings. Seriously, even a loss to the lowly Montreal Alouettes is not enough to take Winnipeg ou…

August 16, 2022

NFL News Bold Predictions for NFL Season Props

The NFL regular season is right around the corner, with Week 1 less than a month away. Before the 103rd season of the NFL kicks off on September 8, we…

August 16, 2022

NFL News NFL Preseason Week 1 – Three Things We Learned

Early Observations The NFL preseason could feel a bit pointless. The games don’t count toward any standings in the league. Head coaches will take va…

August 16, 2022

More NFL Related Articles

Bills vs Rams Matchup Faqs

If you want excitement and great odds with the Bills vs Rams matchup online, BetUS gives the best Vegas NFL odds and the most exciting prop bets. That’s what makes them a good betting option for this game.
If you need to find the Bills vs Rams matchup online to bet on, you can find it on BetUS’s sportsbook site. Just find the FOOTBALL and NFL tabs to bring up the slate of NFL games to wager on. That’s where you will find the Bills vs Rams matchup.
This Bills vs Rams matchup has a betting strategy to use which can help gamblers with their bets on the game.
To make a parlay, simply pick the moneyline, point spread, or over/under of this game along with that of another game. However, you can not parlay a moneyline and point spread from the same game, only different games. The BetUS bet slip will have a PARLAY option to complete your parlay for the Bills vs Rams matchup.
Bet Slip

Your Bet Slip is Empty. To wager with real money...

Fund this wager using a pending wager!

More Details...

Rolling If Bets (RIF) allow you to use the balance (amount) from existing wagers to make a new wager. As long as existing wagers have not been graded, the amount wagered can still be used to make new wagers. However, if your original wager loses, the Rolling If Bet is then cancelled. There are two options for ties (pushes); you can specify if you want the Rolling If Bet to continue in case of a tie or simply cancel the RIF.

Rolling If Bets are:
  • only allowed on straight bets, Parlays and Teasers.
  • not available with Free Plays or Futures and Props
  • only available if you have pre existing, non graded wagers
  • you can only use the funds from the amount of the pre existing wager
How to Place a Rolling If Bet:
  • Choose any straight, parlay or teaser and Place it on the Bet Slip
  • Click on the Rolling If Bet button next to the wager detail
  • In the RIF dropdown, choose a wager that you want to use for RIF
  • Click on "If Win Only" or "If Win or Push" (explained above)
  • Fill in the amount and confirm your wager (the system will not allow you a higher amount than what is available)