The Patriots open their season on the road in a rare Wednesday night kickoff, with Seattle favored at home. NFL odds have the Seahawks at -195 on the moneyline and -3½ on the spread, while New England gets the points at +3½ and comes back at +167 if you’re backing the upset.
A spread in the 3-to-4 point range signals Seattle as the clearer favorite without representing a blowout number, leaving room for New England to keep things competitive behind a healthy gap in moneyline value on both sides. The total sits at 43½, suggesting a moderately paced game rather than one shaping up as a defensive struggle or a track meet.
- Game: Wednesday, September 9, 2026 at 8:20 PM ET
- Moneyline: Seahawks -195 / Patriots +167
- Spread: Seahawks -3½ (-110) / Patriots +3½ (-110)
- Total: 43½ (-110 both sides)