Indianapolis visits U.S. Bank Stadium for an interconference matchup in a series the Colts have historically controlled. Check out our NFL odds as you follow along.
The Colts lead the all-time series 18-9-1, including one playoff win, but Minnesota has won the past two meetings, snapping a six-game losing streak. The most recent was a 21-13 Vikings win in Week 9 of the 2024 season. Before that, Minnesota won 39-36 in overtime in December 2022, while the Colts won 28-11 in 2020, 34-6 in 2016, and 23-20 in 2012.
Storyline: The 2022 meeting produced the largest comeback in NFL history, with Minnesota scoring five touchdowns to erase a 33-0 halftime deficit. The Vikings host the Colts at U.S. Bank Stadium for the third time in five seasons.
Colts at Vikings Match Details
- Game: Sunday, October 25, 2026
- Kickoff: 1:00 PM ET (noon CT)
- Venue: U.S. Bank Stadium, Minneapolis, MN
- Broadcast: CBS
Spread Analysis
The last five meetings split 3-2 in Indianapolis’ favor, but the two most recent went to Minnesota, both at home. As you check the NFL Week 7 odds, the current form points one way: Minnesota is 5-0 coming off its Week 6 bye, while the Colts lost 34-22 at Pittsburgh in Week 5, then gave up a 13-0 halftime lead in a 26-20 Week 6 loss to Tennessee.
The Colts will also be watching the health of Sauce Gardner, who was diagnosed with a mild left calf strain and is considered week-to-week.
Total Betting Trends
Combined scoring in the last five meetings ranged from 34 points in 2024 to 75 points in the 2022 overtime comeback, with the other four games all landing between 34 and 43. Outside of that one record-setting game, this series has stayed in a moderate range, though current offensive form matters most.