NFL Week 7 features an exciting interconference showdown as the Indianapolis Colts travel to U.S. Bank Stadium to take on the Minnesota Vikings. NFL odds have the Vikings as 3-point home favorites at -3 (-115), while the Colts are +3 (-105) on the road. The total is set at 47½ points, with both the Over and Under priced at -110.
A spread of 6½ points indicates Minnesota enters the matchup with a solid edge, benefiting from home-field advantage and expectations of controlling the game. Indianapolis, however, has the opportunity to play spoiler as a live underdog capable of keeping the contest competitive if it can generate timely offensive plays. Meanwhile, the total of 46½ points suggests a balanced matchup, with both teams expected to contribute offensively while their defenses look to create key stops throughout the game.
- Game: Sunday, October 25, 2026 at 1:00 PM ET
- Spread: Vikings -3 (-105) / Colts +3 (-115)
- Total: 47½ (-110 both sides)
