Week 8 stacks headline games across the slate. Miami (FL), sitting at No. 2, meets Louisville on Friday night. That standalone game will set the weekend tone. The SEC takes center stage with No. 6 Alabama vs. No. 11 Tennessee and No. 5 Ole Miss at No. 9 Georgia. Both games carry seeding weight and shape the league’s pecking order.
Out West and in the Midwest, two brand-name clashes pull national interest. No. 13 Notre Dame hosts No. 20 USC. No. 1 Ohio State travels to Wisconsin. On Saturday night, the Holy War takes center stage with No. 15 BYU vs. No. 23 Utah kicking off at 8 PM.
The Week 8 CFB betting board also includes key road tests: No. 21 Texas at Kentucky, No. 10 LSU at No. 17 Vanderbilt, and No. 8 Oregon at Rutgers. Add conference pivots like No. 16 Missouri at Auburn, No. 24 Cincinnati at Oklahoma State, and No. 25 Nebraska at Minnesota.
Join BetUS & Bet Now to lock in spreads, moneylines, totals, alternate lines, first-half odds, and game props. Don’t forget to check out this week’s NFL betting slate.
College Football Week 8 Notable Matchups
Friday, Oct. 17
- No. 2 Miami (FL) vs. Louisville | 7 p.m. | ESPN
Saturday, Oct. 18
- No. 1 Ohio State at Wisconsin | 3:30 p.m. | CBS
- No. 3 Indiana vs. Michigan State | 3:30 p.m. | Peacock
- No. 4 Texas A&M at Arkansas | 3:30 p.m. | ESPN
- No. 5 Ole Miss at No. 9 Georgia | 3:30 p.m. | ABC
- No. 6 Alabama vs. No. 11 Tennessee | 7:30 p.m. | ABC
- No. 7 Texas Tech at Arizona State | 4 p.m. | FOX
- No. 8 Oregon at Rutgers | 6:30 p.m. | BTN
- No. 10 LSU at No. 17 Vanderbilt | 12 p.m. | ABC
- No. 12 Georgia Tech at Duke | 12 p.m. | ESPN
- No. 13 Notre Dame vs. No. 20 USC | 7:30 p.m. | NBC/Peacock
- No. 14 Oklahoma at South Carolina | 12:45 p.m. | SEC Network
- No. 15 BYU vs. No. 23 Utah | 8 p.m. | FOX
- No. 16 Missouri at Auburn | 7 p.m. | SEC Network
- No. 18 Virginia vs. Washington State | 6:30 p.m. | The CW Network
- No. 19 South Florida vs. Florida Atlantic | 7:30 p.m. | ESPNU
- No. 21 Texas at Kentucky | 7 or 7:45 p.m. | ESPN or SEC Network (Flex)
- No. 22 Memphis at UAB | 4 p.m. | ESPN2
- No. 24 Cincinnati at Oklahoma State | 8 p.m. | ESPN2
- No. 25 Nebraska at Minnesota | 8 p.m. | FOX
CFB Betting Markets Explained
You’ll see the core markets first. Use them as your base.
- Point Spreads: Hunt for your number. Shop Week 8 college football spreads across listed games.
- Moneylines: Prefer a straight win? Use NCAAF moneyline odds to target underdog or favorite outcomes.
- Totals: Track college football over/under moves tied to pace, efficiency, and situational edges.
Push further with add-ons:
- Alternate Lines: Shift the spread or total to fit your risk. Trade cushion for price or vice versa.
- CFB game props: Team points, race to 20, margin bands, scoring by half. Quick-hit bets. Clear grading.
- College football player props: Passing, rushing, receiving ladders where available. Perfect for spotlight games.
- Parlays and Same-Game Parlays: Combine markets across Alabama–Tennessee, Ole Miss–Georgia, and Notre Dame–USC. Stack edges. Boost payouts.
- Live betting: Prices update snap to snap. Grab swings. Hedge positions. Press reads.
Your toolkit at BetUS makes CFB Week 8 betting odds easy to browse and act on. Tap, add, confirm. Done.
Key Betting Trends & CFB Line Movement
So, what’s the bottom line? Rivalry weeks invite two forces: public momentum and sharp resistance. Public bettors gravitate to favorites and overs in marquee spots. Sharps probe prices early, then buy back late if the number runs. That tug-of-war moves College Football Week 8 odds all week.
Odds for notable standalone games often shift first. Miami (FL) vs. Louisville headlines Friday’s slate. Early action there can ripple into Saturday bankroll plans, which can affect how bettors approach No. 1 Ohio State at Wisconsin and No. 13 Notre Dame vs. No. 20 USC later in the day. Prime-time showcases like No. 6 Alabama vs. No. 11 Tennessee pull multiplied parlays; that stacking can nudge spreads and totals by kickoff, and you’ll see it on this board.
Ranked vs. ranked games pull two-way money. No. 5 Ole Miss at No. 9 Georgia fits. No. 15 BYU vs. No. 23 Utah fits. Books post fair numbers. Markets test both sides. When prop menus open wider, some bettors pivot from sides to player and team markets. Totals can move on pace notes and weather headlines. If tempo outlooks firm up, you’ll see CFB Week 8 betting odds react. If a QB’s status clears, NCAAF Week 8 lines settle quickly.
Use your tools. Set alerts. Watch the board. Prices don’t wait, and sometimes they sprint when late money hits or when an inactives list drops five minutes before kickoff and everything changes at once.
Injury Report & Impact
Injuries swing prices, but not equally. Quarterbacks shift spreads. Tackles and corners matter more than many think. Skill groups can tilt totals. Track player injury statuses by tag: out, doubtful, questionable, probable. Each label tells a story about risk and potential price movement.
Here’s a clean approach:
- Check each matchup’s notes two to three times: early week, midweek, pregame.
- Watch late scratches in No. 13 Notre Dame vs. No. 20 USC, No. 6 Alabama vs. No. 11 Tennessee, and No. 5 Ole Miss at No. 9 Georgia. Big audiences. Big swings.
- Use alternate lines if volatility rises. Protect your stack. Or press your read at a better number.
BetUS posts updates fast. Use the live board. Stay nimble.
How to Bet on College Football at BetUS
Start Betting On College Football In Minutes:
- Create your account. Fund your dough safely.
- Find “College Football” and tap Week 8.
- Pick a game: Alabama Vs.Tennessee, Ole Miss Vs. Georgia, Notre Dame Vs. USC, BYU Vs. Utah, or any listed matchup.
- Choose your market: spread, moneyline, total, props, or an alternate line.
- Add to bet slip. Enter stake. Confirm.
Popular CFB Betting Examples:
- Simple bet: Take a Week 8 college football spread or a moneyline in No. 1 Ohio State at Wisconsin.
- SGP: Combine Notre Dame team total, a player yardage line, and a margin band.
- Multi-game parlay: Miami (FL) Vs. Louisville total, Texas Vs. Kentucky spread, Oregon Vs. Rutgers moneyline.
Here’s rule number one: set a budget. Guard your stack. Don’t chase. Want flexibility? Use alternate lines to shape risk.