An intriguing interconference matchup is on tap in NFL Week 3 as the Las Vegas Raiders travel to New Orleans to take on the Saints at Caesars Superdome. NFL odds have the Saints as 3-point home favorites at -3 (-110), while the Raiders are +3 (-110) as the road underdog. The total is set at 42½ points, with both the Over and Under priced at -110.
A field-goal spread suggests oddsmakers expect a competitive contest, with New Orleans receiving the edge thanks to home-field advantage. Las Vegas remains a live underdog capable of keeping the game within one possession, while the total of 42½ points points toward a defensive-minded matchup where every scoring opportunity could have a significant impact on the final outcome.
- Game: Sunday, September 27, 2026 at 4:25 PM ET
- Spread: Saints -3 (-110) / Raiders +3 (-110)
- Total: 42½ (-110 both sides)