⚽ Champions League Matchday 1 – Odds Breakdown
The Champions League returns with a bang on September 16-18, 2025, as Europe’s elite clubs kick off the revamped 36-team league phase.
From powerhouses like Real Madrid and Manchester City to ambitious challengers across the continent, the opening matchday delivers compelling storylines and attractive Champions League betting opportunities that’ll keep you glued to your screen.
Here’s a breakdown of the standout matchups and current Champions League odds.
🔥 Tuesday, September 16, 2025
- Real Madrid vs Marseille
Madrid enters as heavy favorites in the Champions League betting odds, though Marseille’s attacking flair could create serious value on the total goals market and alternative handicap lines.
- Juventus vs Borussia Dortmund
Tight handicap market with Juventus at +100 and Dortmund at +270, offering balanced action for both sides in what’s shaping up to be one of the most competitive Champions League bets of the opening week.
Draw sits at +235, reflecting the evenly-matched nature of this fixture where both clubs harbor genuine continental ambitions.
🔥 Wednesday, September 17, 2025
- Bayern Munich vs Chelsea
The German giants welcome Chelsea in what promises to be an entertaining affair, with both clubs carrying rich European pedigrees and attacking philosophies that should produce goals – making the odds on Champions League totals markets particularly appealing for astute bettors.
- Liverpool vs Atlético Madrid
Anfield hosts this heavyweight clash between clubs that know each other well from previous European encounters, creating an atmosphere where anything can happen and the crowd becomes the 12th man, which always factors into smart Champions League betting calculations.
- Paris Saint-Germain vs Atalanta
PSG sits as substantial favorites at -333 against Atalanta’s +700 longshot odds in the Champions League betting odds markets.
The French side’s home advantage and star power make them the clear choice, though Atalanta’s counter-attacking style has troubled bigger clubs before – exactly why seasoned bettors love hunting value in these Champions League bets.
🔥 Thursday, September 18, 2025
- Manchester City vs Napoli
City commands respect at -155 with Napoli returning +400 value for brave bettors looking for substantial returns in the odds on Champions League action.
Both teams bring technical excellence and tactical sophistication that should create an engaging spectacle for viewers and opportunities for those studying Champions League winner odds throughout the tournament.
👉 Overall, the biggest underdog prices land on Atalanta (+700) and Napoli (+400), while favorites like PSG and Manchester City carry the lowest risk but modest returns in the current Champions League betting odds landscape.
Some players have said that winning the UEFA Champions League is bigger than winning the World Cup. Truth or not, it highlights the importance of the soccer club tournament. Of course, such a significant competition is part of BetUS’ grid. Encounter Champions League odds, in-depth previews, news, soccer predictions, and more ahead!
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Champions League Odds at BetUS
After establishing a new format for the 2024-25 season, everything is ready for the UCL to continue its course along that path, a league phase of 36 teams, after which the first eight qualify directly to the Round of 16, and from 9-24 collide in a two-leg playoff to determine the other eight. That means more Champions League bets, and you can find them all at BetUS!
Teams from 53 associations will begin the journey to dethrone PSG in July, and it will finish in May at Puskas Arena in Budapest, where the Grand Finale will take place. We offer Champions League betting odds of all kinds, but getting to know and taking advantage of the most popular is always a smart move, whether you are an experienced bettor or a newcomer!
Handicap
You bet on the favorite with a disadvantage or the underdog with an advantage. Let’s tackle this with an example. Team A is the favorite and offers a -1.5 handicap. That means Team A must win by at least two goals. On the other hand, if you bet on Team B at +1.5, you will win the bet as long as Team B doesn’t lose by two goals or more.
Moneyline
Forget about advantages or disadvantages; here, the Champions League betting action gets easier. You bet straight-up on Team A or Team B winning the game. Additionally, the option to bet on a draw is available.
Totals
If you want to bet on the Champions League but don’t want to think about which team is winning the game, betting on the totals is the way. The only thing that matters is the total number of goals scored by both teams during the game. You can also bet on a specific team total, which narrows the odds to only one of the two teams. If you bet on Team A, scoring more than 1.5 goals, it doesn’t matter if Team B wins 4-2; if Team A scores more than 1.5 goals, you win the bet.
Prop Bets
- Anytime goalscorer: bet on a specific player to score during the game.
- Player to assist: bet on a particular player to assist during the game.
- To win to nil: bet on a team to win while keeping a clean sheet.
- Both Teams to Score: bet on whether both teams will score at least one goal during the game.
- Winning margin: bet on the difference by which Team A or Team B will win.
- Total corners: bet on how many corners there will be in total during the match.
- First/Last team to score: bet on which team will score the first and last goal.
Champions League Outrights
Just as you can take it game by game, play by play, you can also place a long-term bet, also known in this case as Champions League outrights. For example, you could bet right now on which team will win the Champions League title.
The odds are based on each team’s performance and can change after every fixture, but once you place a bet, you are locked in. For example, if you take Real Madrid to win the title at +500, it doesn’t matter if Los Blancos are -250 by the semifinals. Your +500 bet stands until the end.
Besides the winner, you can also take a shot at which teams will reach the final, which team will finish at the bottom, and which player will win the Golden Boot. In other words, you can have a blast before and during the season!
Recap of the 2024-25 Season
Last season, for the fifth time in history, a new champion was crowned in Munich. PSG destroyed Inter Milan and many Champions League bets with a 5-0 victory—the biggest winning margin in a championship game in the modern era.
Curiously enough, PSG didn’t finish the league phase in the top eight. Neither did Real Madrid, Manchester City, nor Juventus. On the other hand, Liverpool, the team at the top of the standings at the end of this phase, was eliminated in the Round of 16.
Aleksander Ceferin, president of UEFA, said that’s precisely what they were aiming for: more games and more chances for all teams.
Individually, Serhou Guirassy and Raphinha finished as the top scorers, with 13 goals each. However, Ousmane Dembele won the Player of the Tournament award, while his teammate Desire Oue won the Young Player of the Tournament. In summary, PSG won it all.
Champions League Betting Odds to Win the 2025-26 Title
Liverpool (+550)
Surprise, surprise! PSG is not atop the UEFA odds to win the upcoming edition of the Champions League. Liverpool, the reigning English Premier League champions, leads Champions League outrights after signing attacking midfielder Florian Wirtz and managing to retain Mohamed Salah.
Real Madrid (+650)
All lists about odds to win the Champions League throne will include Real Madrid, the team with the most titles (15), even more after refurbishing the defensive unit with the signings of Trent Alexander-Arnold and Dean Huijsen. And don’t forget Xabi Alonso, the head coach who led Bayer Leverkusen to winning the Bundesliga without losing a single game.
Barcelona (+700)
Lamine Yamal leads a Barcelona team that reached the semifinals last season. Los Azulgranas also won the La Liga and Copa del Rey titles. They were so dominant that they defeated Real Madrid four times in a row. Los Azulgranas don’t even need reinforcements to appear on this list.
PSG (+700)
When discussing soccer futures, the reigning champions certainly deserve respect. PSG will try to become the second team in the modern era to win back-to-back UCL titles. Luckily for them, no crucial player left the team after winning the treble.
Dark Horses
Inter Milan, one of last season’s finalists, offers a +2200 price. Despite losing head coach Simone Inzaghi to Al Hilal, the Nerazzurri managed to retain all top players and made several signings, including Luis Henrique and Ange-Yoan Bonny.
Borussia Dortmund at +5000 is another deal to keep an eye on. The Black and Yellows are a feisty underdog and signed Jobe Bellingham, Jude Bellingham’s brother, a rising star who is only 19.
Champions League Last 10 Winners
- Paris Saint-Germain (France)
- Real Madrid (Spain)
- Manchester City (England)
- Real Madrid (Spain)
- Chelsea (England)
- Bayern Munich (Germany)
- Liverpool (England)
- Real Madrid (Spain)
- Real Madrid (Spain)
- Real Madrid (Spain)
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