Another AFC game with the division lead on the line. The Colts have lost two in a row and are only 2-3 away from home as they head to Jacksonville.
NFL odds have the Jags as one-point favorites. The total is 47½ points.
Jonathan Taylor will need to have a big game to maintain his lead in the rushing race. James Cook has closed within 54 yards of the NFL leader.
ook for the Colts to bounce back and regain their stride.