An exciting interconference matchup highlights the NFL Week 5 schedule as the Philadelphia Eagles travel to EverBank Stadium to take on the Jacksonville Jaguars. NFL odds have the Eagles as 3-point road favorites at -3 (-110), while the Jaguars are +3 (-110) at home. The total is set at 46½ points, with both the Over and Under priced at -110.
Philadelphia enters as the road favorite, reflecting confidence in the Eagles’ overall roster strength and ability to perform in a challenging environment. Jacksonville remains a dangerous home underdog with enough offensive talent to keep the game competitive and potentially pull off the upset. The 3-point spread suggests a closely contested matchup, while the total of 46½ points points toward a balanced offensive battle where execution in key situations could decide the outcome.
- Game: Sunday, October 11, 2026 at 9:30 AM ET
- Spread: Eagles -3 (-110) / Jaguars +3 (-110)
- Total: 46½ (-110 both sides)